Results 1 to 10 of about 19,050 (169)

Imipramine poisoning. [PDF]

open access: bronzeArchives of Disease in Childhood, 1971
D J Bain, T Turner
openalex   +4 more sources

Imipramine Inhibits Chikungunya Virus Replication in Human Skin Fibroblasts through Interference with Intracellular Cholesterol Trafficking

open access: yesScientific Reports, 2017
Chikungunya virus (CHIKV) is an emerging arbovirus of the Togaviridae family that poses a present worldwide threat to human in the absence of any licensed vaccine or antiviral treatment to control viral infection. Here, we show that compounds interfering
Sineewanlaya Wichit   +16 more
semanticscholar   +1 more source

Imipramine Protects against Bone Loss by Inhibition of Osteoblast-Derived Microvesicles

open access: yesInternational Journal of Molecular Sciences, 2017
The maintenance of bone homeostasis is largely dependent upon cellular communication between osteoclasts and osteoblasts. Microvesicles (MVs) represent a novel mechanism for osteoblasts and osteoclasts communication, as has been demonstrated in our ...
L. Deng   +7 more
semanticscholar   +1 more source

Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole

open access: yesParasites & Vectors, 2016
BackgroundImipramine, a tricyclic antidepressant widely used clinically, has other pharmacological effects, such as antileishmanial activity. Tricyclic antidepressants interact with lipid bilayers, and some studies have shown that imipramine inhibits ...
V. V. Andrade-Neto   +3 more
semanticscholar   +1 more source

Metabolomic identification of biochemical changes induced by fluoxetine and imipramine in a chronic mild stress mouse model of depression

open access: yesScientific Reports, 2015
Metabolomics was applied to a C57BL/6N mouse model of chronic unpredictable mild stress (CMS). Such mice were treated with two antidepressants from different categories: fluoxetine and imipramine.
J. Zhao   +5 more
semanticscholar   +1 more source

IL-4/10 prevents stress vulnerability following imipramine discontinuation

open access: yesJournal of Neuroinflammation, 2015
BackgroundIdentifying stress vulnerability after antidepressant discontinuation may be useful in treating relapses in depression. Previous studies have suggested significant effects of the immune system as well as the central nervous system (CNS) on ...
Arum Han   +6 more
semanticscholar   +1 more source

Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial.

open access: yesJournal of the American Medical Association (JAMA), 2000
CONTEXT Panic disorder (PD) may be treated with drugs, psychosocial intervention, or both, but the relative and combined efficacies have not been evaluated in an unbiased fashion. OBJECTIVE To evaluate whether drug and psychosocial therapies for PD are
David H. Barlow   +3 more
semanticscholar   +1 more source

Imipramine for neuropathic pain in adults.

open access: yesCochrane Database of Systematic Reviews, 2014
BACKGROUND Antidepressants are widely used to treat chronic neuropathic pain (pain due to nerve damage), usually in doses below those at which they exert antidepressant effects.
L. Hearn   +4 more
semanticscholar   +1 more source

Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice.

open access: yesAmerican Journal of Physiology - Gastrointestinal and Liver Physiology, 2012
Our previous data showed the inhibitory effect of ethanol on AMP-activated protein kinase phosphorylation, which appears to be mediated, in part, through increased levels of hepatic ceramide and activation of protein phosphatase 2A (Liangpunsakul S ...
S. Liangpunsakul   +5 more
semanticscholar   +1 more source

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