Results 1 to 10 of about 38,471 (252)

Chronic imipramine treatment-induced changes in acetylcholinesterase (EC 3.1.1.7) activity in discrete rat brain regions [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Cholinergic as well as monoaminergic neurotransmission seems to be involved in the etiology of affective disorders. Chronic treatment with imipramine, a classical antidepressant drug, induces adaptive changes in monoaminergic neurotransmission.
R. Camarini, M.A.C. Benedito
doaj   +3 more sources

Intratympanic dexamethasone as an adjuvant to oral imipramine hydrochloride (Tofranil, a TCA) 25 mg twice daily in management of idiopathic unilateral subjective tinnitus

open access: diamondThe Egyptian Journal of Otolaryngology, 2019
Background In this report, we summarize our clinical experience with intratympanic (IT) dexamethasone treatment for control of idiopathic unilateral tinnitus when used as an adjunct treatment with Tricyclic antidepressant (TCA) imipramine hydrochloride ...
Tamer A. Abo El Ezz   +2 more
doaj   +2 more sources

A Comparative Survey of the Effects of Fluoxetine and Imipramine on Depression-Like Behavior and Serum Levels of Corticosterone and Glucose in Male Rats under Immobilization Stress

open access: diamondMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: Depression is one of the most common psychiatric disorders, which can be detected and continued through stressful life events.
Razieh Bayramlou   +2 more
doaj   +2 more sources

Imipramine and Depression [PDF]

open access: bronzeBritish Journal of Psychiatry, 1977
R J, Kerry, J E, Orme
openaire   +3 more sources

Antidepressant and Anxiolytic Effect of Tramadol as Compared to Imipramine, in Acute and Chronic Dosage in Rats

open access: yesJournal of Aziz Fatimah Medical and Dental College, 2022
Objective: To assess the anti-depressant and anxiolytic effect of tramadol as compared to imipramine (approved antidepressant) in acute and chronic doses in rats.
Fiza Soomro   +3 more
doaj   +1 more source

Further characterization of the effect of the prototypical antidepressant imipramine on the microstructure of licking for sucrose.

open access: yesPLoS ONE, 2021
We previously reported that treatment with the prototypical antidepressant imipramine induced a dose-dependent reduction of the ingestion of a 10% sucrose solution, due to reduction of the licking burst number, thus suggesting reduced motivation and/or ...
Paolo S D'Aquila, Adriana Galistu
doaj   +1 more source

Suppression of EGFR/PKC-δ/NF-κB Signaling Associated With Imipramine-Inhibited Progression of Non-Small Cell Lung Cancer

open access: yesFrontiers in Oncology, 2021
BackgroundAnti-depressants have been reported to own anti-tumor potential types of cancers; however, the role of imipramine in non-small cell lung cancer (NSCLC) has not been elucidated.
Po-Fu Yueh   +9 more
doaj   +1 more source

Effects of imipramine on cancer patients over-expressing Fascin1; description of the HITCLIF clinical trial

open access: yesFrontiers in Oncology, 2023
BackgroundTumor invasion and metastasis are responsible for the majority of cancer-related deaths. The identification of molecules involved in these processes is crucial to design effective treatments that can halt the progression of cancer.
Antonio Asensi-Cantó   +8 more
doaj   +1 more source

Time of Administration of Acute or Chronic Doses of Imipramine Affects its Antidepressant Action in Rats

open access: yesJournal of Circadian Rhythms, 2018
The pathogenesis and therapeutics of depression are linked to the operation of the circadian system. Here, we studied the chronopharmacological action of a tricyclic antidepressant, imipramine. Male adult Wistar–Hannover rats were administered imipramine
Hiroshi Kawai   +6 more
doaj   +1 more source

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