Association Between Plasma SITH-1 Antibody Titers and Treatment Trajectory of Treatment-Resistant Depression. [PDF]
Neuropsychopharmacol RepThis study investigated whether SITH‐1, a latent HHV‐6B protein that promotes neuroinflammation, is associated with the clinical trajectory of treatment‐resistant depression (TRD). We demonstrated significantly elevated SITH‐1 titers and a correlation with the number of depressive episodes, suggesting that SITH‐1 may serve as a novel biomarker for TRD.
Mori K +5 more
europepmc +2 more sources
Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. [PDF]
, 2004 We studied the influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. Both single and chronic administration of imipramine potently shortened immobility in naive rats during forced-swim testing.
Araki, Hiroaki +5 more
core +1 more source
Modulation of 8-OH-DPAT-Induced Hypothermia by Imipramine in Rats
Journal of Pharmacological Sciences, 2003 : The effects of imipramine on 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), the 5-hydroxytryptamine (5-HT)1A-receptor full agonist, -induced hypothermia was examined in rats.
Yoshihisa Kitamura +4 more
doaj +1 more source
Veterinary Sciences, 2021 Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects.
Geng-Ruei Chang +8 more
doaj +1 more source
Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]
, 2010 We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato +9 more
core +1 more source
The effect of imipramine on the behavior of albino mice in presence of selenium
Libyan International Medical University Journal, 2016 Introduction: Imipramine, a tricyclic antidepressant used in the treatment of depression, anxiety, and other mental condition. Selenium is useful in managing depression and anxiety.
S Aburawi, S Baayo
doaj +1 more source
Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. [PDF]
, 2017 Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML).
Arbiser, Jack L +6 more
core +1 more source
Neural Regeneration Research, 2016 Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process.
Ming-lei Han +4 more
doaj +1 more source
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]
, 2011 The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali +6 more
core +5 more sources
Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]
, 2015 Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta +6 more
core +4 more sources