<i>Oroxylum indicum</i> (L.) Bark Ameliorates Anxiety and Depression: Evidence From Experimental and Computational Studies. [PDF]
Food Sci NutrThe study evaluated the antioxidant and neuropharmacological effects of Oroxylum indicum bark (MOIB), identifying 20 phytochemicals through GC–MS analysis. MOIB exhibited anxiolytic, sedative, and antidepressant effects in various behavioral tests, with two compounds (CID 550198 and CID 10393) showing strong binding affinities to targeted receptors and
Aktaruzzaman M +12 more
europepmc +2 more sources
Beyond Oral Pain: A Unique Case of Burning Mouth Syndrome With Coexisting Vulvodynia and Cognitive Impairment in a Postmenopausal Woman. [PDF]
Clin Case RepABSTRACT Burning mouth syndrome (BMS) is a chronic pain condition characterized by persistent intraoral burning without an identifiable cause, predominantly affecting postmenopausal women. We present a unique case of a 63‐year‐old Ethiopian woman exhibiting a distinctive triad of BMS, vulvodynia, and progressive cognitive decline, an association not ...
Annam R, De Onaindia M, Partin C.
europepmc +2 more sources
Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]
, 2010 We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato +9 more
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The effect of imipramine on the behavior of albino mice in presence of selenium
Libyan International Medical University Journal, 2016 Introduction: Imipramine, a tricyclic antidepressant used in the treatment of depression, anxiety, and other mental condition. Selenium is useful in managing depression and anxiety.
S Aburawi, S Baayo
doaj +1 more source
Veterinary Sciences, 2021 Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects.
Geng-Ruei Chang +8 more
doaj +1 more source
Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells. [PDF]
, 2017 Aberrant cytokine signaling initiated from mutant receptor tyrosine kinases (RTKs) provides critical growth and survival signals in high risk acute myeloid leukemia (AML).
Arbiser, Jack L +6 more
core +1 more source
Neural Regeneration Research, 2016 Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process.
Ming-lei Han +4 more
doaj +1 more source
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]
, 2011 The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali +6 more
core +5 more sources
Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice [PDF]
, 2015 Poor micturition control may cause profound distress, because proper voiding is mandatory for an active social life. Micturition results from the subtle interplay of central and peripheral components.
Antonio, Caretta +6 more
core +4 more sources
Journal of Pharmacological Sciences, 2003 We previously reported that NG108-15 cells contain intrinsic serotonin 2C receptor (5-HT2CR). The effects of imipramine, a 5-HT2CR antagonist, on cell growth, cell viability, and the 5-HT2CR mRNA level were investigated in this study.
Monrudee Sukma +2 more
doaj +1 more source