Results 21 to 30 of about 19,050 (169)
Biological and Pharmaceutical Bulletin, 2011 Adult hippocampal neurogenesis is reported to change in animal models of depression and antidepressants. We have used the mitotic marker 5-bromo-2'-deoxyyridine to address the effects of imipramine and lithium on cell proliferation and survival following
Y. Kitamura +10 more
semanticscholar +1 more source
Veterinary Record Case Reports, EarlyView.Abstract A 3‐year‐old, male, entire, German wirehaired pointer dog was presented with a 2‐year history of paroxysmal episodes of collapse associated with reduced levels of consciousness. A magnetic resonance imaging study identified a single, ill‐defined, non‐contrast‐enhancing, intra‐axial mass lesion involving the hypothalamus.
Callum Atkins +3 more
wiley +1 more source
Imipramine in patients with chest pain despite normal coronary angiograms.
New England Journal of Medicine, 1994 BACKGROUND Ten to 30 percent of patients undergoing cardiac catheterization because of chest pain are found to have normal coronary angiograms. Because these patients may have a visceral pain syndrome unrelated to myocardial ischemia, we investigated ...
R. Cannon +11 more
semanticscholar +1 more source
Opportunities and Challenges of Population Pharmacogenomics
Annals of Human Genetics, EarlyView.ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou +3 more
wiley +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, EarlyView.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Narcolepsy and rapid eye movement sleep
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Pharmacokinetics of Amoxicillin in the Cat
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT The pharmacokinetics and plasma protein binding of amoxicillin in cats has not been thoroughly investigated. In a single‐group sequential designed experimental study, amoxicillin was administered to six healthy cats intravenously, orally, and subcutaneously.
Ilse R. Dubbelboer +6 more
wiley +1 more source
Harmine and Imipramine Promote Antioxidant Activities in Prefrontal Cortex and Hippocampus
Oxidative Medicine and Cellular Longevity, 2010 A growing body of evidence has suggested that reactive oxygen species (ROS) may play an important role in the physiopathology of depression. Evidence has pointed to the β-carboline harmine as a potential therapeutic target for the treatment of depression.
G. Réus +8 more
semanticscholar +1 more source
British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1899-1913, July 2025.Aims To identify, evaluate and summarize all published literature that investigated manipulations to pharmaceutical dosage forms of psychotropic medications that could be used for the purposes of tapering. Methods A systematic literature review was carried out of the available published literature on manipulations performed to psychotropic medications ...
Denis O'Brien +3 more
wiley +1 more source