Results 21 to 30 of about 49,920 (311)

Effects of imipramine on cancer patients over-expressing Fascin1; description of the HITCLIF clinical trial

open access: yesFrontiers in Oncology, 2023
BackgroundTumor invasion and metastasis are responsible for the majority of cancer-related deaths. The identification of molecules involved in these processes is crucial to design effective treatments that can halt the progression of cancer.
Antonio Asensi-Cantó   +8 more
doaj   +1 more source

Understanding and treating ejaculatory dysfunction in men with diabetes mellitus

open access: yesAndrology, Volume 11, Issue 2, Page 379-398, February 2023., 2023
Abstract Diabetes mellitus is a rapidly rising metabolic disorder with important systemic complications. Global figures have demonstrated the prevalence of diabetes mellitus has almost quadrupled from 108 million in 1980 to 422 million in 2014, with a current prevalence of over 525 million.
Ankit Desai   +4 more
wiley   +1 more source

Further characterization of the effect of the prototypical antidepressant imipramine on the microstructure of licking for sucrose.

open access: yesPLoS ONE, 2021
We previously reported that treatment with the prototypical antidepressant imipramine induced a dose-dependent reduction of the ingestion of a 10% sucrose solution, due to reduction of the licking burst number, thus suggesting reduced motivation and/or ...
Paolo S D'Aquila, Adriana Galistu
doaj   +1 more source

Time of Administration of Acute or Chronic Doses of Imipramine Affects its Antidepressant Action in Rats

open access: yesJournal of Circadian Rhythms, 2018
The pathogenesis and therapeutics of depression are linked to the operation of the circadian system. Here, we studied the chronopharmacological action of a tricyclic antidepressant, imipramine. Male adult Wistar–Hannover rats were administered imipramine
Hiroshi Kawai   +6 more
doaj   +1 more source

Influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. [PDF]

open access: yes, 2004
We studied the influence of imipramine on the duration of immobility in chronic forced-swim-stressed rats. Both single and chronic administration of imipramine potently shortened immobility in naive rats during forced-swim testing.
Araki, Hiroaki   +5 more
core   +1 more source

Ovarian Gene Transcriptional Responses To Antidepressant Drugs (Imipramine And Fluoxetine) In Female Wistar Rats [PDF]

open access: yes, 2023
This study was designed to investigate ovarian gene transcriptional responses to selected antidepressant drugs (imipramine and fluoxetine) in female rats. Fifteen female rats (120 – 140 g) were used for this study. Imipramine (0.71 mg/kg) and fluoxetine (
D., Uwadiale, K.O., Oyedeji
core   +2 more sources

Experience of antidepressant use and discontinuation: A qualitative synthesis of the evidence

open access: yesJournal of Psychiatric and Mental Health Nursing, Volume 30, Issue 1, Page 21-34, February 2023., 2023
Accessible Summary What is known on the subject? Rates of antidepressant prescribing have been increasing. Antidepressants are not effective for many people. What the paper adds to existing knowledge? Participants described how in order to receive help they had to engage with a medical pathway in which their experiences were constructed as arising from
Marie Crowe, Maree Inder, Cate McCall
wiley   +1 more source

Effects of Imipramine and Lithium on the Suppression of Cell Proliferation in the Dentate Gyrus of the Hippocampus in Adrenocorticotropic Hormone-treated Rats [PDF]

open access: yes, 2010
We examined the influence of chronic adrenocorticotropic hormone (ACTH) treatment on the number of Ki-67-positive cells in the dentate gyrus of the hippocampus in rats. ACTH treatment for 14 days decreased the number of such cells.
Asanuma, Masato   +9 more
core   +1 more source

Imipramine protects retinal ganglion cells from oxidative stress through the tyrosine kinase receptor B signaling pathway

open access: yesNeural Regeneration Research, 2016
Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process.
Ming-lei Han   +4 more
doaj   +1 more source

Imipramine Accelerates Nonalcoholic Fatty Liver Disease, Renal Impairment, Diabetic Retinopathy, Insulin Resistance, and Urinary Chromium Loss in Obese Mice

open access: yesVeterinary Sciences, 2021
Imipramine is a tricyclic antidepressant that has been approved for treating depression and anxiety in patients and animals and that has relatively mild side effects.
Geng-Ruei Chang   +8 more
doaj   +1 more source

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