Results 41 to 50 of about 49,920 (311)

Metabolomic identification of biochemical changes induced by fluoxetine and imipramine in a chronic mild stress mouse model of depression

Scientific Reports, 2015
Metabolomics was applied to a C57BL/6N mouse model of chronic unpredictable mild stress (CMS). Such mice were treated with two antidepressants from different categories: fluoxetine and imipramine.
J. Zhao, Yang-Hee Jung, C. Jang, Kwang-Hoon Chun, S. Kwon, Jeongmi Lee   +5 more
semanticscholar   +1 more source

Development and validation of spectrophotometric method for determination of imipramine hydrochloride in tablets (solid materials)

Journal of King Saud University: Science, 2022
In the presented work, potassium dichromate in the presence of sulfuric acid was used as a reagent for spectrophotometric determination of imipramine HCl concentration in tablet formulations.
Syed Najmul Hejaz Azmi, Zayana Nasser Al-Masrouri, Ibtisam Rashid Al-Lamki, Afrah Khamis Al-Jabri, Nafisur Rahman, Mohd Nasir, Kamal Abdelrahman, Mohmmed S. Fnais, Mahbbob Alam   +8 more
doaj  

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans [PDF]

, 2014
Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra.
A Garcia-Espana, A Moszczynska, A Priyadarshi, Alexander Holmes, Anton Gartner, AT Allen, B Giros, C Boucheix, C Boucheix, C Boucheix, C Klein, C Missale, CD Dunn, CH Lai, D Vallone, DB Calne, DL Chase, E Rubinstein, E Rubinstein, EA Bolan, ER Sawin, ES Calipari, FJ Lee, FJ Lee, GC Cotzias, GR Uhl, H Maharaj, H Moribe, H Moribe, HP Rang, J Bove, J Sulston, JE Galvin, JG White, JM Beaulieu, JW Langston, K Jellinger, K Strange, K Tieu, KF Tipton, Kim A. Caldwell, L Carvelli, LD Jayanthi, M Santiago, MJ Ferris, MJ LaVoie, MJ Zigmond, ML Toth, MS Szczypka, MW Davis, MY Chang, N Chen, Neda Masoudi, O Thompson, P Seeman, P Seeman, P Sokoloff, Pablo Ibanez-Cruceyra, PW McDonald, QY Zhou, R Andrew, R Nass, R Nass, RM Kostrzewa, RR Gainetdinov, S Brenner, S Cao, S Charrin, S Fahn, S Fahn, S Thaminy, Sarah-Lena Offenburger, TN Chase, W Birkmayer, WA Cass, Y Glinka   +75 more
core   +4 more sources

IL-4/10 prevents stress vulnerability following imipramine discontinuation

Journal of Neuroinflammation, 2015
BackgroundIdentifying stress vulnerability after antidepressant discontinuation may be useful in treating relapses in depression. Previous studies have suggested significant effects of the immune system as well as the central nervous system (CNS) on ...
Arum Han, Hye-Rin Yeo, Min-Jung Park, S. H. Kim, H. Choi, C. Hong, M. Kwon   +6 more
semanticscholar   +1 more source

Erratum: Effects of imipramine on cancer patients over-expressing Fascin1; description of the HITCLIF clinical trial [PDF]

Frontiers in Oncology
Frontiers Production Office
doaj   +2 more sources

Cognitive-behavioral therapy, imipramine, or their combination for panic disorder: A randomized controlled trial.

Journal of the American Medical Association (JAMA), 2000
CONTEXT Panic disorder (PD) may be treated with drugs, psychosocial intervention, or both, but the relative and combined efficacies have not been evaluated in an unbiased fashion. OBJECTIVE To evaluate whether drug and psychosocial therapies for PD are
David H. Barlow, J. Gorman, M. Shear, S. Woods   +3 more
semanticscholar   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N, Bergstrom RF, Bravo L, Bremner JD, Burrows GD, Chouinard G, Datla KP, Esther Berrocoso, Juan Antonio Mico, Kreiss DS, Laura Perez-Caballero, Lemberger L, Li Q, Lidia Bravo, Maj J, Nibuya M, Owens MJ, Rutter JJ, Sonia Torres-Sanchez, Stevens JC, Wong DT   +20 more
core   +2 more sources

Imipramine for neuropathic pain in adults.

Cochrane Database of Systematic Reviews, 2014
BACKGROUND Antidepressants are widely used to treat chronic neuropathic pain (pain due to nerve damage), usually in doses below those at which they exert antidepressant effects.
L. Hearn, S. Derry, Tudor J. C. Phillips, R. A. Moore, P. Wiffen   +4 more
semanticscholar   +1 more source

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A., Ebel, Jana-Fabienne, Hose, Matthias [u.v.m.], Japtok, Lukasz, Klopfleisch, Robert, Meiners, Jana, Palmieri, Vittoria, Schumacher, Fabian, Yusuf, Ayan Mohamud, Zöller, Julia   +9 more
core   +1 more source

Floppy iris syndrome with oral imipramine: A case series

Indian Journal of Ophthalmology, 2012
Intraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy.
Arvind Gupta, Renuka Srinivasan
doaj   +1 more source