Results 51 to 60 of about 49,920 (311)

Intratympanic dexamethasone as an adjuvant to oral imipramine hydrochloride (Tofranil, a TCA) 25 mg twice daily in management of idiopathic unilateral subjective tinnitus

The Egyptian Journal of Otolaryngology, 2019
Background In this report, we summarize our clinical experience with intratympanic (IT) dexamethasone treatment for control of idiopathic unilateral tinnitus when used as an adjunct treatment with Tricyclic antidepressant (TCA) imipramine hydrochloride ...
Tamer A. Abo El Ezz, Fathy N. Fattoh, Tahany Rabie   +2 more
doaj   +1 more source

Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study

Pathogens, 2022
Bluetongue virus (BTV), an arbovirus of ruminants, is a causative agent of numerous epidemics around the world. Due to the emergence of novel reassortant BTV strains and new outbreaks, there is an unmet need for efficacious antivirals.
Lijo John, Caroline Vernersson, Hyesoo Kwon, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +5 more
doaj   +1 more source

Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]

, 2002
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph, Grunze, Heinz, Marcuse, Alain, Schaerer, Lars O., Walden, Jörg   +4 more
core   +1 more source

Imipramine blocks ethanol-induced ASMase activation, ceramide generation, and PP2A activation, and ameliorates hepatic steatosis in ethanol-fed mice.

American Journal of Physiology - Gastrointestinal and Liver Physiology, 2012
Our previous data showed the inhibitory effect of ethanol on AMP-activated protein kinase phosphorylation, which appears to be mediated, in part, through increased levels of hepatic ceramide and activation of protein phosphatase 2A (Liangpunsakul S ...
S. Liangpunsakul, Yasmeen Rahmini, R. A. Ross, Zhenwen Zhao, Yan Xu, D. Crabb   +5 more
semanticscholar   +1 more source

Role of aqueous extract of Crocus sativus to improvement of sexual dysfunctions induced by imipramine in male mice

The Iraqi Journal of Veterinary Medicine, 2017
The present study was carried out to focus light on the possible improvement and enhancement of functional performance of male mice sexual activities by using the aqueous extract of Crocus sativus.
Salma J. Askar
doaj   +1 more source

Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration.

International Journal of Neuropsychopharmacology, 2012
A growing body of evidence indicates that facilitation of serotonin-2C receptor (5-HT2CR)-mediated neurotransmission in the basolateral nucleus of the amygdala (BLA) is involved in anxiety generation.
M. Vicente, H. Zangrossi
semanticscholar   +1 more source

Effects of Tibetan medicine metacinnabar (β-HgS) combined with imipramine or sertraline on depression-like symptoms in mice

Frontiers in Pharmacology, 2022
Depression is a common mood disorder that has exhibited an increased incidence rate worldwide, but the overall clinical efficacy of antidepressants remains unsatisfactory.
Yajun Qiao, Yajun Qiao, Yajun Qiao, Cen Li, Cen Li, Ming Zhang, Ming Zhang, Xingfang Zhang, Xingfang Zhang, Lixin Wei, Lixin Wei, Keshen Cao, Xiaoyuan Zhang, Hongtao Bi, Tingting Gao, Tingting Gao   +15 more
doaj   +1 more source

Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects [PDF]

, 2004
Reboxetine is a selective noradrenaline reuptake inhibitor, whereas mirtazapine acts as an antagonist at noradrenergic alpha(2), serotonin (5-HT2), 5-HT3 and histamine H-1 receptors.
Baghai, Thomas C., Laakmann, G., Schule, C.   +2 more
core   +1 more source

Imipramine Is an Orally Active Drug against Both Antimony Sensitive and Resistant Leishmania donovani Clinical Isolates in Experimental Infection

PLoS Neglected Tropical Diseases, 2012
Background In an endeavor to find an orally active and affordable antileishmanial drug, we tested the efficacy of a cationic amphiphilic drug, imipramine, commonly used for the treatment of depression in humans.
S. Mukherjee, B. Mukherjee, Rupkatha Mukhopadhyay, Kshudiram Naskar, S. Sundar, J. Dujardin, A. Das, Syamal Roy   +7 more
semanticscholar   +1 more source

A clinical review of enuresis and its associated psychiatric comorbidities

Annals of Indian Psychiatry, 2022
Enuresis is a common childhood condition treated by pediatricians and psychiatrists. Enuresis is also commonly referred as bedwetting. It is more prevalent among boys than girls. Enuresis is an involuntary voiding of urine continuing after an anticipated
Rachana Pole, Ganpatlal Kodarbhai Vankar, Ajinkya Sureshrao Ghogare   +2 more
doaj   +1 more source