Results 121 to 130 of about 29,009 (218)

The regulation of the PD-1/PD-L1 pathway in imiquimod-induced chronic psoriasis itch and itch sensitization in mouse

Molecular Pain
PD-1/PD-L1 inhibitors have been demonstrated to induce itch in both humans and experimental animals. However, whether the PD-1/PD-L1 pathway is involved in the regulation of chronic psoriatic itch remains unclear. This study aimed to investigate the role
Zhehao Xu, Yue Wang, Changcheng Jiang, Zhengwei Wang, YongFeng Cheng, Manli Fan   +5 more
doaj   +1 more source

T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets

Aging Cell, Volume 25, Issue 5, May 2026.
Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu, Ming Yang, Fugang Xiao, Jinrong Zeng   +3 more
wiley   +1 more source

Immunotherapy with imiquimod in cervical, vaginal, and vulvar intraepithelial lesions – a review of the literature

Libri Oncologici
Imiquimod is a topical immunomodulatory agent commonly used in treating various skin conditions, including precancerous lesions. This review summarizes current evidence on the efficacy and safety of imiquimod for treating vaginal, cervical, and vulvar ...
Damir Danolić, Luka Marcelić, Lucija Šušnjar, Ilija Alvir, Ivica Mamić, Domagoj Dobranić, Darko Tomica, Tomislav Bečejac, Domagoj Vidosavljević, Mario Puljiz   +9 more
doaj   +1 more source

An NIR‐II Absorbing Injectable Hydrogel for Boosted Photo‐Immunotherapy Toward Human Papillomavirus Associated Cancer

Aggregate
Human papillomavirus (HPV) is a highly prevalent venereal pathogen accounting for genital warts and various cancers like cervical, anal, and oropharyngeal cancers.
Xinghua Yu, Lingan Zeng, Xinyue Yang, Zuliang Ren, Xuemei Dong, Ge Meng, Guogang Shan, Dingyuan Yan, Dong Wang, Fei Sun   +9 more
doaj   +1 more source

The clinical observation on the treatment of multiple plantar warts with plum-blossom needling combined with tazarotene cream and imiquimod cream

Pifu-xingbing zhenliaoxue zazhi
Objective To observe the efficacy of plum-blossom needling combined with tazarotene cream and imiquimod cream in the treatment of multiple plantar warts. Methods Sixty patients with multiple plantar warts were randomly divided into the observation group,
LI Fengchun, XU Jiaoxiong, HE Renliang, LI Hui, YAN Lijuan, MA Yunan   +5 more
doaj   +1 more source

Could Inflammaging and Its Sequelae Be Prevented or Mitigated? [PDF]

, 2019
Aged humans display a chronic and low-grade inflammation, termed "inflammaging", which has been potentially linked to the subsequent development of some aging-associated systemic disorders, including type 2 diabetes, atherosclerotic cardiovascular ...
Elias, Peter M, Man, Mao-Qiang
core  

Etiologia, diagnóstico e tratamento do carcinoma verrucoso [PDF]

, 2017
O carcinoma verrucoso caracteriza-se como uma variante do carcinoma espinocelular, sendo a cavidade oral o local onde surge mais frequentemente. Trata-se de um tumor localmente invasivo mas com baixo potencial de metastização.
Maciel, Vera Marina
core  

What is the most effective treatment for external genital warts? [PDF]

, 2002
Podofilox (Condylox), imiquimod (Aldara), cryotherapy, and surgical options all seem reasonable alternatives that are superior to podophyllin. (Grade of recommendation: B, based on systematic review.) No studies of surgical options versus home use ...
French, Linda, Nashelsky, Joan
core  

TLR7/8 signaling balances cytokine responses in neonatal monocytes. [PDF]

Sci Rep
Dreschers S, Heiler E, Oppermann L, Gille C, Hornef M, Orlikowsky TW.   +5 more
europepmc   +1 more source

Clinical and Virologic Outcomes of Topical Imiquimod in Vaginal Intraepithelial Neoplasia: A Retrospective Cohort Study. [PDF]

J Clin Med
Vural NA, Aldıkaçtıoğlu Talmaç M, Günay İ, Temel Yüksel İ, Güner G, Canaz E, Turan H, Erdem B, Kocadal NÇ.   +8 more
europepmc   +1 more source