Results 1 to 10 of about 322,405 (217)

Comparative effectiveness and prescribing trends of modified release versus immediate release indapamide in patients with hypertension: cohort study [PDF]

open access: yesBMJ Medicine
Objective To investigate the prescribing trends of indapamide, a thiazide-like diuretic, and the long term comparative effectiveness of modified release versus immediate release indapamide.Design Cohort study.Setting IQVIA Medical Research Data UK ...
Li Wei   +9 more
doaj   +2 more sources

Immediate release fentanyl in general practices: Mostly off-label prescribing [PDF]

open access: yesEuropean Journal of General Practice, 2023
Background The immediacy of the onset of opioids may be associated with the risk of dependency and accidental overdose. Nasal and oromucosal fentanyl dosage forms are so called immediate release fentanyl (IRF).
Yvette M. Weesie   +3 more
doaj   +2 more sources

How to Obtain the Maximum Properties Flexibility of 3D Printed Ketoprofen Tablets Using Only One Drug-Loaded Filament?

open access: yesMolecules, 2021
The flexibility of dose and dosage forms makes 3D printing a very interesting tool for personalized medicine, with fused deposition modeling being the most promising and intensively developed method.
Jolanta Pyteraf   +10 more
doaj   +1 more source

Tramadol Steady-State Pharmacokinetics of Immediate-Release Capsules and Sustained-Release Tablets in Dogs

open access: yesFuture Pharmacology, 2022
Tramadol is a veterinary analgesic for dogs. In this study, the steady-state pharmacokinetics of a sustained-release (SR) tablet (Tramagetic OD®) and immediate-release capsules (IR) were compared. In a crossover design, six dogs received five doses of IR
Esther Winter   +4 more
doaj   +1 more source

A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis

open access: yesOrphanet Journal of Rare Diseases, 2021
Background Nephropathic cystinosis is a rare and severe metabolic disease leading to an accumulation of cystine in lysosomes which especially harms kidney function.
Christina van Stein   +7 more
doaj   +1 more source

Optimization of Preparation Process and Pharmacokinetics of APAP Double-Release Pellet Capsules [PDF]

open access: yesBIO Web of Conferences, 2023
In order to develop a kind of APAP double-release pellet capsules, which was prepared with the manual filling method, the immediate and sustained release pellets of a certain proportion were prepared by the fluidized bed coating and the extrusion ...
Zhang Ningning   +5 more
doaj   +1 more source

Treatment-Continuity of ADHD Compared Using Immediate-Release and Extended-Release MPH

open access: yesPediatric Neurology Briefs, 2005
The continuity of methylphenidate (MPH) therapy for ADHD in young Medicaid beneficiaries (ages 6 to 17 years) treated with immediate-release (IR) or extended-release (ER) MPH formulations was compared in an analysis of statewide California Medicaid ...
J Gordon Millichap
doaj   +1 more source

Long-term clinical benefits of delayed-release cysteamine bitartrate capsules in patients with nephropathic cystinosis (response to “A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis”)

open access: yesOrphanet Journal of Rare Diseases, 2023
The aim of this letter to the editor is to summarize the results from three clinical trial programs evaluating delayed-release cysteamine bitartrate (DR-CYS), which demonstrated the long-term clinical benefits in patients with nephropathic cystinosis ...
Craig B. Langman
doaj   +1 more source

Dual Release Paracetamol in Osteoarthritis of Knee: A Randomized Controlled Clinical Trial [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Background: Paracetamol is recommended as first line agent for pain management in osteoarthritis (OA) by various guidelines. The main problem associated with management of osteoarthritis is long term patient compliance to paracetamol due to its ...
Vishwnath Yaligod   +8 more
doaj   +1 more source

Insights into the Control of Drug Release from Complex Immediate Release Formulations

open access: yesPharmaceutics, 2021
The kinetics of water transport into tablets, and how it can be controlled by the formulation as well as the tablet microstructure, are of central importance in order to design and control the dissolution and drug release process, especially for ...
Runqiao Dong   +5 more
doaj   +1 more source

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