Results 1 to 10 of about 322,306 (116)

Comparative effectiveness and prescribing trends of modified release versus immediate release indapamide in patients with hypertension: cohort study [PDF]

open access: yesBMJ Medicine
Objective To investigate the prescribing trends of indapamide, a thiazide-like diuretic, and the long term comparative effectiveness of modified release versus immediate release indapamide.Design Cohort study.Setting IQVIA Medical Research Data UK ...
Li Wei   +9 more
doaj   +2 more sources

Immediate release fentanyl in general practices: Mostly off-label prescribing [PDF]

open access: yesEuropean Journal of General Practice, 2023
Background The immediacy of the onset of opioids may be associated with the risk of dependency and accidental overdose. Nasal and oromucosal fentanyl dosage forms are so called immediate release fentanyl (IRF).
Yvette M. Weesie   +3 more
doaj   +2 more sources

Targeted Development of an Optimised Formulation for 3D-Printing of a Sertraline Hydrochloride-Containing Drug Delivery System with Immediate-Release Characteristics Utilising a Mixture Design [PDF]

open access: yesPharmaceutics
Objectives: Although 3D-printing has been identified as a promising technique for personalised medicine manufacturing, developing complex formulations that are suitable for the process can be challenging.
Mirco Bienhaus   +3 more
doaj   +2 more sources

Development of Personalised Immediate-Release Gel-Based Formulations Using Semi-Solid Extrusion [PDF]

open access: yesGels
Precision in dosing is crucial for optimizing therapeutic outcomes and preventing overdosing, especially in preterm infants. Traditional manual adjustments to adapt the dose often lead to inaccuracies, contamination risks, and reduced precision.
Morenikeji Aina   +6 more
doaj   +2 more sources

Tramadol Steady-State Pharmacokinetics of Immediate-Release Capsules and Sustained-Release Tablets in Dogs

open access: yesFuture Pharmacology, 2022
Tramadol is a veterinary analgesic for dogs. In this study, the steady-state pharmacokinetics of a sustained-release (SR) tablet (Tramagetic OD®) and immediate-release capsules (IR) were compared. In a crossover design, six dogs received five doses of IR
Esther Winter   +4 more
doaj   +1 more source

Quality by Design Applied Development of Immediate-Release Rabeprazole Sodium Dry-Coated Tablet

open access: yesPharmaceutics, 2021
The aim of this study was to develop immediate-release oral rabeprazole sodium tablets with rapid efficacy and gastric stability for the treatment of gastroesophageal reflux disease.
Sang-Ho Lee, Joo-Eun Kim
doaj   +1 more source

A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis

open access: yesOrphanet Journal of Rare Diseases, 2021
Background Nephropathic cystinosis is a rare and severe metabolic disease leading to an accumulation of cystine in lysosomes which especially harms kidney function.
Christina van Stein   +7 more
doaj   +1 more source

Treatment-Continuity of ADHD Compared Using Immediate-Release and Extended-Release MPH

open access: yesPediatric Neurology Briefs, 2005
The continuity of methylphenidate (MPH) therapy for ADHD in young Medicaid beneficiaries (ages 6 to 17 years) treated with immediate-release (IR) or extended-release (ER) MPH formulations was compared in an analysis of statewide California Medicaid ...
J Gordon Millichap
doaj   +1 more source

Electrospun Janus Beads-On-A-String Structures for Different Types of Controlled Release Profiles of Double Drugs

open access: yesBiomolecules, 2021
A side-by-side electrospinning process characterized by a home-made eccentric spinneret was established to produce the Janus beads-on-a-string products.
Ding Li   +4 more
doaj   +1 more source

Immediate release drug delivery systems: a current update

open access: yesJournal of Applied Pharmaceutical Research, 2018
Instead of tremendous advancements in drug delivery, the oral route remains the most preferred route for the administration of therapeutic agents because of the low cost of therapy and ease of administration that leads to high levels of patient ...
Suman Saha
doaj   +1 more source

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