Results 11 to 20 of about 322,455 (262)

Insights into the Control of Drug Release from Complex Immediate Release Formulations [PDF]

open access: yesPharmaceutics, 2021
The kinetics of water transport into tablets, and how it can be controlled by the formulation as well as the tablet microstructure, are of central importance in order to design and control the dissolution and drug release process, especially for ...
Runqiao Dong   +5 more
doaj   +4 more sources

Single- and multiple-dose pharmacokinetics of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) compared with immediate-release hydrocodone bitartrate/ibuprofen and immediate-release tramadol HCl/acetaminophen

open access: yesJournal of Pain Research, 2015
Krishna Devarakonda,1 Kenneth Kostenbader,2 Michael J Giuliani,3 Jim L Young41Department of Clinical Pharmacology, Mallinckrodt Pharmaceuticals, 2Mallinckrodt Pharmaceuticals, 3Research and Development, Mallinckrodt Pharmaceuticals, 4Department of ...
Devarakonda K   +3 more
doaj   +5 more sources

Design and optimization of immediate release tablet of salbutamol sulphate by direct compression technique

open access: yesJournal of Applied Pharmaceutical Research, 2018
This study is about a tablet, which disintegrates or dissolves quickly when placed in the oral cavity. Studies on formulation development of Salbutamol Sulphate Immediate Release Tablet, suitable for manufacturing by direct compression have been carried ...
Suman Saha
doaj   +1 more source

A clinical study to compare the efficacy and safety of pregabalin sustained release formulation with pregabalin immediate release formulation in patients of diabetic peripheral neuropathic pain

open access: yesIndian Journal of Endocrinology and Metabolism, 2012
Objective: To compare the efficacy and safety of sustained release (SR) formulation of pregabalin with immediate release (IR) formulation in patient with diabetic peripheral neuropathic pain.
A Srivastava   +16 more
doaj   +1 more source

Production of Reproducible Filament Batches for the Fabrication of 3D Printed Oral Forms

open access: yesPharmaceutics, 2021
Patients need medications at a dosage suited to their physiological characteristics. Three-dimensional printing (3DP) technology by fused-filament fabrication (FFF) is a solution for manufacturing medication on demand.
Stéphane Roulon   +6 more
doaj   +1 more source

Rapid Preparation of Spherical Granules via the Melt Centrifugal Atomization Technique

open access: yesPharmaceutics, 2019
Granules with superior fluidity and low moisture absorption are ideal for tableting and capsule filling. Melt granulation as a solvent-free technology has attracted increasing interest for the granulation of moisture-sensitive drugs. The objective of the
Yan Yang   +5 more
doaj   +1 more source

Application of hydroxypropylated crosslinked starch from the grains of Oryza sativa L. as potential disintegrant in compressed solid dosage form. [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2022
Context: The modification of starch from the grains of NSICRc222 rice variety may provide a new material with enhanced disintegrating functionality in compressed solid dosage forms.
Elizabeth A. Pagtalunan   +2 more
doaj  

Optimization of Preparation Process and Pharmacokinetics of APAP Double-Release Pellet Capsules [PDF]

open access: yesBIO Web of Conferences, 2023
In order to develop a kind of APAP double-release pellet capsules, which was prepared with the manual filling method, the immediate and sustained release pellets of a certain proportion were prepared by the fluidized bed coating and the extrusion ...
Zhang Ningning   +5 more
doaj   +1 more source

Long-term clinical benefits of delayed-release cysteamine bitartrate capsules in patients with nephropathic cystinosis (response to “A comparison of immediate release and delayed release cysteamine in 17 patients with nephropathic cystinosis”)

open access: yesOrphanet Journal of Rare Diseases, 2023
The aim of this letter to the editor is to summarize the results from three clinical trial programs evaluating delayed-release cysteamine bitartrate (DR-CYS), which demonstrated the long-term clinical benefits in patients with nephropathic cystinosis ...
Craig B. Langman
doaj   +1 more source

Immediate-release versus controlled-release carbamazepine in the treatment of epilepsy [PDF]

open access: yesCochrane Database of Systematic Reviews, 2016
Epilepsy is defined as the tendency to spontaneous, excessive neuronal discharge manifesting as seizures. It is a common disorder with an incidence of 50 per 100,000 per year and a prevalence of 0.5% to 1% in the developed world (Hauser 1993).Carbamazepine (CBZ) is a widely used antiepileptic drug that is associated with a number of troublesome adverse
Graham, Powell   +3 more
openaire   +3 more sources

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