Results 11 to 20 of about 75,693 (242)
Critical pathways in cellular senescence and immortalization revealed by gene expression profiling
Michael A Tainsky
exaly +2 more sources
Novel cell lines derived from Chinese hamster kidney tissue.
Immortalized kidney cell lines are widely used in basic and applied research such as cell permeability tests and drug screening. Although many cell lines have been established from kidney tissues, the immortalization process has not been clarified in ...
Yoshinori Kawabe, Masamichi Kamihira
doaj +1 more source
Development and characterization of a new human hepatic cell line [PDF]
The increasing demand and hampered use of primary human hepatocytes for research purposes have urged scientists to search for alternative cell sources, such as immortalized hepatic cell lines.
Berx, Geert +6 more
core +4 more sources
Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization. [PDF]
Persistent infection with high-risk human papillomavirus (HPV) is a major risk factor for cervical cancer. Greater than 90% of these cancers originate in the cervical transformation zone (TZ), a narrow region of metaplastic squamous epithelium that ...
Han Deng +4 more
doaj +1 more source
Immortalization of primary marmoset skin fibroblasts by CRISPR-Cas9-mediated gene targeting
Immortalized cell lines can be used for diverse in vitro experiments, providing invaluable data before conducting in vivo studies Callithrix jacchus, the common marmoset, is a non-human primate model utilized for studying various human diseases. However,
Yeon-Ju Jeong +4 more
doaj +1 more source
An infinite cell line is one of the most favored experimental tools and plays an irreplaceable role in cell-based biological research. Primary cells from normal animal tissues undergo a limited number of divisions and subcultures in vitro before they ...
Dongxue Guo +4 more
doaj +1 more source
Alternatives for obtaining a continuous cell line from Apis mellifera
: In worldwide there are reports of a significant decrease in colonies of the species Apis mellifera, caused by several factors, including viral infections.
Matheus Iuri Frühauf +7 more
doaj +1 more source
Establishment of A Reversibly Inducible Porcine Granulosa Cell Line
Granulosa cells (GCs) are the key components of ovarian follicles for regulating oocyte maturation. Previous established GC lines have allowed prolonged proliferation, but lost some physiological features owing to long-term immortalization.
Yinshan Bai +8 more
doaj +1 more source

