Results 81 to 90 of about 2,846 (189)

Safety and Effectiveness of PCSK9 Inhibitors and Inclisiran in Patients With Neuromuscular Disorders and Statin Intolerance

European Journal of Neurology, Volume 32, Issue 6, June 2025.
ABSTRACT Background and Objectives Limited data exist on the efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors and inclisiran among patients with neuromuscular disorders and statin‐induced myotoxicity and/or hepatotoxicity.
Aikaterini Theodorou, Georgia Papagiannopoulou, Alexandra Akrivaki, Stella Fanouraki, Christos Moschovos, Marianna Papadopoulou, Lina Palaiodimou, Foteini Merkouri, Konstantinos Melanis, Stauroula Salakou, Dimitrios Kitsos, Vaia Lambadiari, Vasiliki Zouvelou, Georgios Papadimas, Sotirios Giannopoulos, Andrei V. Alexandrov, Georgios Tsivgoulis   +16 more
wiley   +1 more source

Rituximab in the treatment of immune-mediated necrotizing myopathy: a review of case reports and case series [PDF]

, 2021
Anji Xiong, Guancui Yang, Zhuoyao Song, Chen Xiong, Liu Deng, Shuai Yu, Linqian He, Liangwen Zhang, Zepeng Guo, Shiquan Shuai   +9 more
openalex   +1 more source

Muscle MRI in immune-mediated necrotizing myopathy (IMNM): implications for clinical management and treatment strategies [PDF]

, 2022
Laura Fionda, Antonio Lauletta, Luca Leonardi, Jorge Alonso‐Pérez, Stefania Morino, Gioia Merlonghi, Girolamo Alfieri, Rocco Costanzo, Laura Tufano, Fiammetta Vanoli, Elena Rossini, Eduard Gallardo Vigo, Tommaso Tartaglione, Marco Salvetti, Giovanni Antonini, Jordi Díaz‐Manera, Matteo Garibaldi   +16 more
openalex   +1 more source

Miopatías inflamatorias

Revista Médica Clínica Las Condes, 2018
RESUMEN: Las miopatías inflamatorias son un grupo heterogéneo de enfermedades adquiridas del músculo estriado esquelético que comparten la injuria muscular inmunomediada como característica común.
Jorge A. Bevilacqua, MD, PhD, Nicholas Earle, MD   +1 more
doaj  

Immune-mediated Necrotizing Myopathy in a Patient with Microscopic Polyangiitis

Internal Medicine
We herein report a case of immune-mediated necrotizing myopathy (IMNM) in a patient with microscopic polyangiitis (MPA). A 77-year-old Japanese woman presented with a 2-day history of proximal muscle weakness and myalgia, with elevated serum creatinine kinase (CK) levels.
Umemoto, Daichi, Kanzawa, Yohei, Nakamura, Tomoko, Nishino, Ichizo, Mizuki, Shimpei, Ohnishi, Jun, Nakajima, Takahiro, Ishimaru, Naoto, Kinami, Saori   +8 more
openaire   +2 more sources

Alpha‐Synuclein as a Potential Biomarker for Inclusion Body Myositis in Blood and Muscle

Neuropathology and Applied Neurobiology, Volume 51, Issue 3, June 2025.
We examined alpha‐synuclein in muscle and serum samples of patients with IBM and other neuromuscular disorders. With the use of immunohistochemistry, we identify alpha‐synuclein muscular reactivity as a complementary diagnostic marker. Serum alpha‐synuclein levels measured by ELISA were not generally altered in IBM but correlated with disease duration ...
Tobias Mayer, Leila Scholle, Laura Foerster, Ilka Schneider, Gisela Stoltenburg‐Didinger, Karl‐Stefan Delank, Thomas Kendzierski, Anna Koelsch, Kathleen Kleeberg, Torsten Kraya, Lorenzo Barba, Steffen Naegel, Anne Schänzer, Markus Otto, Alexander Mensch   +14 more
wiley   +1 more source

From Multi‐Omics to Visualization and Beyond: Bridging Micro and Macro Insights in CAR‐T Cell Therapy

Advanced Science, Volume 12, Issue 20, May 29, 2025.
This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong, Peng Fei, Yicheng Zhang, Yang Xu, Jia Wei   +4 more
wiley   +1 more source

Case Report: Immune Mediated Necrotizing Myopathy With IgG Antibodies to 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase (HMGCR) May Present With Acute Systolic Heart Failure [PDF]

, 2020
Malik Ghannam, Georgios Manousakis
openalex   +1 more source

Immune-Mediated Necrotizing Myopathy - A case report [PDF]

, 2020
A Silva
openalex   +1 more source

AB0871 REMISSION IN ANTI-HMGCR POSITIVE IMMUNE-MEDIATED NECROTIZING MYOPATHY WITHOUT THE USE OF GLUCOCORTICOIDS: A MULTICENTRIC STUDY OF 24 PATIENTS [PDF]

, 2023
D. Martínez-López, D. Prieto-Peña, C. Corrales-Selaya, Piotr Szczęsny, Antonella Notarnicola, R. Blanco, Ingrid E. Lundberg, Maryam Dastmalchi   +7 more
openalex   +1 more source