Results 11 to 20 of about 3,611,485 (197)

Immune complement activation is attenuated by surface nanotopography

International Journal of Nanomedicine, 2011
Mats Hulander1, Anders Lundgren1, Mattias Berglin1, Mattias Ohrlander2, Jukka Lausmaa3,4, Hans Elwing1 1Department of Cell and Molecular Biology/Interface Biophysics, University of Gothenburg, Medicinaregatan 9E, Gothenburg, 2Bactiguard AB, Stockholm ...
Elwing H, Lausmaa J, Ohrlander M, Berglin M, Lundgren A, Hulander M   +5 more
doaj   +1 more source

Data from: Independent and interactive effects of immune activation and larval diet on adult immune function, growth and development in the greater wax moth (Galleria mellonella)

, 2021
Organisms in the wild are likely to face multiple immune challenges as well as additional ecological stressors, yet their interactive effects on immune function are poorly understood.
Krams, Indrikis,University of Tartu, Pölkki, Mari,University of Turku, Krama, Tatjana,Daugavpils University, Valtonen, Terhi M.,University of Turku, Kecko, Sanita,Daugavpils University, Kangassalo, Katariina,University of Turku, Sorvari, Jouni,University of Eastern Finland, Rantala, Markus J.,University of Turku   +7 more
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HIV Patients Treated with Low-dose Prednisolone Exhibit Lower Immune Activation than Untreated Patients. [PDF]

, 2012
HIV-associated general immune activation is a strong predictor for HIV disease progression, suggesting that chronic immune activation may drive HIV pathogenesis. Consequently, immunomodulating agents may decelerate HIV disease progression.
Schmidt, Barabara, Albrecht Ulmer, Norbert Donhauser, Hartwig Klinker, Scheller Carsten, Scheller, Carsten, Kasang Christa, Barbara Schmidt, Stich, August, Schmidt, Barbara, Koutsilieri, Eleni, Ulmer Albrecht, Kalluvya, Samuel, Donhauser Norbert, Koutsilieri Eleni, Kalluvya Samuel, Klinker, Hartwig, Rethwilm, Axel, Axel Rethwilm, August Stich, Schmidt Barbara, Christa Kasang, Stich August, Ulmer, Albrecht, Klinker Hartwig, Samuel Kalluvya, Carsten Scheller, Donhauser, Norbert, Rethwilm Axel, Eleni Koutsilieri, Kasang, Christa   +30 more
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Not All Immune Checkpoints Are Created Equal

Frontiers in Immunology, 2018
Antibodies that block T cell inhibition via the immune checkpoints CTLA-4 and PD-1 have revolutionized cancer therapy during the last 15 years. T cells express additional inhibitory surface receptors that are considered to have potential as targets in ...
Annika De Sousa Linhares, Judith Leitner, Katharina Grabmeier-Pfistershammer, Peter Steinberger   +3 more
doaj   +1 more source

B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments

eLife, 2019
Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto ...
Sophie I Roper, Laabiah Wasim, Dessislava Malinova, Michael Way, Susan Cox, Pavel Tolar   +5 more
doaj   +1 more source

Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness

Journal of Neuroinflammation, 2022
Saturated very long-chain fatty acids (VLCFA, ≥ C22), enriched in brain myelin and innate immune cells, accumulate in X-linked adrenoleukodystrophy (X-ALD) due to inherited dysfunction of the peroxisomal VLCFA transporter ABCD1.
Bettina Zierfuss, Agnieszka Buda, Andrea Villoria-González, Maxime Logist, Jure Fabjan, Patricia Parzer, Claire Battin, Streggi Vandersteene, Inge M. E. Dijkstra, Petra Waidhofer-Söllner, Katharina Grabmeier-Pfistershammer, Peter Steinberger, Stephan Kemp, Sonja Forss-Petter, Johannes Berger, Isabelle Weinhofer   +15 more
doaj   +1 more source

Using the Jurkat reporter T cell line for evaluating the functionality of novel chimeric antigen receptors

Frontiers in Molecular Medicine, 2023
Background: T cells that are genetically modified with chimeric antigen receptor (CAR) hold promise for immunotherapy of cancer. Currently, there are intense efforts to improve the safety and efficacy of CAR T cell therapies against liquid and solid ...
Farhana Jahan, Jan Koski, Diana Schenkwein, Seppo Ylä-Herttuala, Seppo Ylä-Herttuala, Helka Göös, Sini Huuskonen, Markku Varjosalo, Pilvi Maliniemi, Judith Leitner, Peter Steinberger, Hans-Jörg Bühring, Kim Vettenranta, Kim Vettenranta, Matti Korhonen   +14 more
doaj   +1 more source

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
Simon C Watkins, Normolle, D, Kader, M, Elizabeth R Wonderlich, Guiducci, C, Smith, Amanda P., Watkins, SC, Amanda P. Smith (437248), Normolle, Daniel, Watkins Simon C., Franck J. Barrat (437251), Smith Amanda P., Simon M Barratt-Boyes, Daniel Normolle, Daniel Normolle (437250), Barrat Franck J., Simon M. Barratt-Boyes (264203), Normolle Daniel, Wonderlich Elizabeth R., Franck J Barrat, Barratt-Boyes Simon M., Guiducci, Cristiana, Barrat, Franck J., Kader, Muhamuda, Guiducci Cristiana, Wonderlich, ER, Cristiana Guiducci, Barrat, FJ, Watkins, Simon C., Amanda P Smith, Barratt-Boyes, SM, Muhamuda Kader, Smith, AP, Wonderlich, Elizabeth R., Cristiana Guiducci (437249), Simon C. Watkins (39900), Barratt-Boyes, Simon M., Muhamuda Kader (437247), Elizabeth R. Wonderlich (270792), Kader Muhamuda   +39 more
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Lymphocyte activation gene-3 : the expression and function in the immune system [PDF]

, 2006
Lymphocyte activation gene-3 (LAG-3) is the structural homologue of a well-known TCR co-receptor CD4. Recently, it has been suggested that LAG-3 might play a role in modulation of immune response, by being a negative regulator of T cell activation. To
Kisielow, Malgorzata
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A strong immune response in young adult honeybees masks their increased susceptibility to infection compared to older bees [PDF]

, 2012
Honeybees, Apis mellifera, show age-related division of labor in which young adults perform maintenance ("housekeeping") tasks inside the colony before switching to outside foraging at approximately 23 days old. Disease resistance is an important feature
Baxter, LA, James C Bull, Bull James C., Ryabov, EV, Laura A. Baxter, Baxter Laura A., Mead, A, Pell, JK, Judith K. Pell (107694), Laura A Baxter, Osborne Juliet L., Ryabov, Eugene V., Chandler, D, Prince Gill, Judith K. Pell¤b, Juliet L Osborne, Prince, G, Osborne, Juliet L., Osborne, JL, Judith K Pell, Cunjin Zhang, Prince, Gillian, Dave Chandler (107700), Zhang, C., Laura A. Baxter (107691), Ryabov, E. V., Zhang Cunjin, Dave Ch, Chandler Dave, Baxter, L. A., Juliet L. Osborne¤c, James C. Bull (107677), Pell Judith K., Ryabov Eugene V., Baxter, Laura, James Bull, Chandler, Dave, Eugene V. Ryabov (107680), Mead, A. (Andrew), Zhang, Cunjin, Eugene V Ryabov, Andrew Mead, Cunjin Zhang (107690), James C. Bull, Mead Andrew, Chandler, D., Gill Prince, Bull, James C., Prince, G., Pell, Judith K., Dave Chandler, Pell, J. K., Osborne, J. L., Juliet L. Osborne (107697), Zhang, C, Andrew Mead (107686), Mead, A., Bull, JC, Bull, J. C., Eugene V. Ryabov, Gill Prince (107683)   +60 more
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