Results 281 to 290 of about 1,693,225 (311)

Decidual Immune Cell Infiltrate in Hydatidiform Mole

Cancer Investigation, 2009
Hydatidiform mole is a gestational trophoblastic disease characterized by proliferation of the pregnancy-associated trophoblastic tissue. Complete hydatidiform mole is an entirely paternally derived lesion, and therefore, represents complete intrauterine allografts that can induce an altered maternal immune response Hypothesis: Here, we hypothesize ...
Mahmoud R, Hussein, Ahmad Rezk, Abd-Elwahed, Eman Sayed, Abodeif, Saad Rezk, Abdulwahed   +3 more
openaire   +2 more sources

Immunohistochemical evaluation of immune cell infiltration in canine gliomas

Veterinary Pathology, 2021
Evasion of the immune response is an integral part of the pathogenesis of glioma. In humans, important mechanisms of immune evasion include recruitment of regulatory T cells (Tregs) and polarization of macrophages toward an M2 phenotype. Canine glioma has a robust immune cell infiltrate that has not been extensively characterized.
Gregory A. Krane, Carly A. O’Dea, David E. Malarkey, Andrew D. Miller, C. Ryan Miller, Debra A. Tokarz, Heather L. Jensen, Kyathanahalli S. Janardhan, Keith R. Shockley, Norris Flagler, Brittani A. Rainess, Christopher L. Mariani   +11 more
openaire   +2 more sources

Glofitamab stimulates immune cell infiltration of CNS tumors and induces clinical responses in secondary CNS lymphoma.

Blood
Although CD20xCD3 bispecific antibodies are effective against systemic B-cell lymphomas, their efficacy in CNS lymphoma is unknown. Here, we report the CD20xCD3 bispecific, glofitamab, penetrates the blood-brain barrier, stimulates immune-cell ...
James K Godfrey, Lei Gao, G. Shouse, Joo Y Song, Stacy Pak, Brian Lee, Bihong T. Chen, A. Kallam, John H. Baird, Guido Marcucci, Lucy Y. Ghoda, Stephanie Vauleon, Alexey V Danilov, A. Herrera, Larry W. Kwak, L. Budde   +15 more
semanticscholar   +1 more source

Tumor infiltrating immune cells in gliomas and meningiomas

Brain, Behavior, and Immunity, 2016
Tumor-infiltrating immune cells are part of a complex microenvironment that promotes and/or regulates tumor development and growth. Depending on the type of cells and their functional interactions, immune cells may play a key role in suppressing the tumor or in providing support for tumor growth, with relevant effects on patient behavior.
Domingues, Patrícia, González-Tablas, María, Otero, Álvaro, Pascual, Daniel, Miranda, David, Ruiz, Laura, Sousa, Pablo, Ciudad, Juana, Gonçalves, Jesús María, Lopes, María Celeste, Orfao de Matos Correia e Vale, José Alberto, Tabernero, María Dolores   +11 more
openaire   +4 more sources

Characterization of the immune cell infiltration landscape in lung adenocarcinoma

Archives of Biochemistry and Biophysics, 2022
Immune checkpoint inhibitors (ICIs) have played an important role in the treatment of lung adenocarcinoma (LUAD). However, their effectiveness is limited, and many patients exhibit a weak response. In this study, we propose a new and more effective immunophenotyping method for evaluating the prognosis and tumor microenvironment (TME) cellular ...
Hai-Bin, Ou, Yan, Wei, Yu, Liu, Fu-Xiang, Zhou, Yun-Feng, Zhou   +4 more
openaire   +2 more sources

Immune cell infiltration of normal and impaired sow endometrium

Animal Reproduction Science, 2004
The paper reviews the physiological infiltration of immune cells, leukocytes, in the sow endometrium during different stages of the normal oestrous cycle, after mating and during early pregnancy. The mechanisms for development of endometritis in relation to oestrous cycle stages are also described.
A-M, Dalin, K, Kaeoket, E, Persson
openaire   +2 more sources

Characterization of Immune Cell Infiltration Into Canine Intracranial Meningiomas

Veterinary Pathology, 2011
Meningiomas are the most common intracranial tumors in dogs. A variety of inflammatory cells have been shown to invade these tumors in people, but little is known about interactions between the immune system and naturally occurring brain tumors in dogs.
L B, Boozer, T W, Davis, L B, Borst, K M, Zseltvay, N J, Olby, C L, Mariani   +5 more
openaire   +2 more sources

Immune cell infiltrates and prognosis in primary carcinoma of the lung

Lung Cancer, 2000
The prognostic significance of immune cell infiltrates in surgically resected human lung cancer was investigated in 710 patients. Lymphoid infiltrates were quantified on both standard H&E stained sections and, in a subset of 95 cases, using immunohistochemistry and antibodies to CD3, CD8, CD57, CD68, CD79a and S100 to identify various immune cell types.
S K, Johnson, K M, Kerr, A D, Chapman, M M, Kennedy, G, King, J S, Cockburn, R R, Jeffrey   +6 more
openaire   +2 more sources

Characterization of endometriosis-associated immune cell infiltrates (EMaICI)

Archives of Gynecology and Obstetrics, 2016
To identify and characterize endometriosis-associated immune cell infiltrates (EMaICI). Furthermore, to define occurrence and size of EMaICI in various types of endometriosis.Immune cells were characterized in samples of 60 premenopausal women with histological proven endometriosis. Therefore, immunohistochemical staining with monoclonal antibodies for
Claudia, Scheerer, Petia, Bauer, Vito, Chiantera, Jalid, Sehouli, Andreas, Kaufmann, Sylvia, Mechsner   +5 more
openaire   +2 more sources

Phenotyping of immune cell infiltrates in breast and colorectal tumours

Immunological Investigations, 1999
White cell infiltration of solid tumors is an important prognostic indicator in malignant disease. Although macrophage infiltration is associated with good outcome in colorectal cancer, a high macrophage content is associated with poor prognosis in breast cancer. Suppressor macrophages prevent T cell activation in normal tissues such as mucosal linings
D, Toomey, J, Harmey, C, Condron, E, Kay, D, Bouchier-Hayes   +4 more
openaire   +2 more sources