Results 11 to 20 of about 14,522,121 (350)
Cell Death and Disease, 2023 The tumor microenvironment (TME) is a highly intricate milieu, comprising a multitude of components, including immune cells and stromal cells, that exert a profound influence on tumor initiation and progression.
Jianwen Fang +7 more
semanticscholar +1 more source
Functional status analysis of RNH1 in bladder cancer for predicting immunotherapy response
Scientific Reports, 2023 Bladder cancer (BLCA) typically has a poor prognosis due to high rates of relapse and metastasis. Although the emergence of immunotherapy brings hope for patients with BLCA, not all patients will benefit from it.
Sen Chen +7 more
doaj +1 more source
Frontiers in Microbiology, 2022 Talaromyces amestolkiae is an important fungal species owing to its ubiquity in soils, plants, air, and food. In this study, we identified a novel six-segmented polymycovirus, Talaromyces amestolkiae polymycovirus 1 (TaPmV-1). Each of the double-stranded
Li Teng +12 more
doaj +1 more source
Cellular & Molecular Immunology, 2020 Immunotherapy has revolutionized cancer treatment and rejuvenated the field of tumor immunology. Several types of immunotherapy, including adoptive cell transfer (ACT) and immune checkpoint inhibitors (ICIs), have obtained durable clinical responses, but
Yuanyuan Zhang, Zemin Zhang
semanticscholar +1 more source
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
Nature Communications, 2022 A major rate-limiting step in developing more effective immunotherapies for GBM is our inadequate understanding of the cellular complexity and the molecular heterogeneity of immune infiltrates in gliomas. Here, we report an integrated analysis of 201,986
Nourhan Abdelfattah +19 more
semanticscholar +1 more source
Translational Oncology, 2022 The immunosuppressive tumor microenvironment (TME) is the main reason for the failure of many immunotherapies that directly stimulate anti-tumor immune response.
Xuan Lin +11 more
doaj +1 more source
Key chemokines direct migration of immune cells in solid tumors
Cancer Gene Therapy, 2021 Immune cell infiltration into solid tumors, their movement within the tumor microenvironment (TME), and interaction with other immune cells are controlled by their directed migration towards gradients of chemokines.
Karan Kohli +2 more
semanticscholar +1 more source
Immune Cells in the BBB Disruption After Acute Ischemic Stroke: Targets for Immune Therapy?
Frontiers in Immunology, 2021 Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic transformation.
Yan-mei Qiu +6 more
semanticscholar +1 more source
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+FoxP3+ regulatory T cells activation [PDF]
, 2020 Rationale: Loss of histone macroH2A1 induces appearance of cancer stem cells (CSCs)-like cells in hepatocellular carcinoma (HCC). How CSCs interact with the tumor microenvironment and the adaptive immune system is unclear. Methods: We screened aggressive
Drovakova A. +11 more
core +1 more source
Cancers, 2022 Simple Summary The relationship between the immune system and tumours is currently one of the most studied topics in the field of cancer. Previously, it was thought that a tumour could be malignant on its own; nonetheless, nowadays, we know that it needs
Alicia Cristina Peña-Romero +1 more
semanticscholar +1 more source