Results 11 to 20 of about 3,195,227 (346)
Immune cells and non-immune cells with immune function in mammalian cochleae [PDF]
Hearing Research, 2018 The cochlea has an immune environment dominated by macrophages under resting conditions. When stressed, circulating monocytes enter the cochlea. These immune mediators, along with cochlear resident cells, organize a complex defense response against pathological challenges.
Bo Hua, Hu +2 more
openaire +2 more sources
Translational Oncology, 2022 The immunosuppressive tumor microenvironment (TME) is the main reason for the failure of many immunotherapies that directly stimulate anti-tumor immune response.
Xuan Lin +11 more
doaj +1 more source
Stem Cell Reports, 2015 Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation ...
Danika M. Khong +11 more
doaj +1 more source
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]
, 2017 Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick +12 more
core +1 more source
Cell Reports, 2014 Thymic epithelial cells (TECs) are critical for T cell development and self-tolerance but are gradually lost with age. The existence of thymic epithelial progenitors (TEPCs) in the postnatal thymus has been inferred, but their identity has remained ...
Kahlia Wong +9 more
doaj +1 more source
Construction of a serum diagnostic signature based on m5C-related miRNAs for cancer detection
Frontiers in Endocrinology, 2023 Currently, no clinically relevant non-invasive biomarkers are available for screening of multiple cancer types. In this study, we developed a serum diagnostic signature based on 5-methylcytosine (m5C)-related miRNAs (m5C-miRNAs) for multiple-cancer ...
Fuzhou Tang +7 more
doaj +1 more source
Dissecting interferon-induced transcriptional programs in human peripheral blood cells [PDF]
, 2010 Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell ...
David A. Relman +7 more
core +9 more sources
Vaccines, 2023 The administration of mRNA-based tumour vaccines is considered a promising strategy in tumour immunotherapy, although its application against kidney renal clear cell carcinoma (KIRC) is still at its infancy stage.
Shichao Zhang +7 more
doaj +1 more source
Megakaryocytes as immune cells [PDF]
Journal of Leukocyte Biology, 2019 Abstract Platelets play well-recognized roles in inflammation, but their cell of origin—the megakaryocyte—is not typically considered an immune lineage. Megakaryocytes are large polyploid cells most commonly identified in bone marrow. Egress via sinusoids enables migration to the pulmonary capillary bed, where elaboration of platelets ...
Pierre, Cunin, Peter A, Nigrovic
openaire +2 more sources