Results 21 to 30 of about 14,522,121 (350)
Stem Cell Reports, 2015 Mechanisms underlying age-related defects within lymphoid-lineages remain poorly understood. We previously reported that sex steroid ablation (SSA) induced lymphoid rejuvenation and enhanced recovery from hematopoietic stem cell (HSC) transplantation ...
Danika M. Khong +11 more
doaj +1 more source
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]
, 2017 Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick +12 more
core +1 more source
Dissecting interferon-induced transcriptional programs in human peripheral blood cells [PDF]
, 2010 Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell ...
David A. Relman +7 more
core +9 more sources
Cell Reports, 2014 Thymic epithelial cells (TECs) are critical for T cell development and self-tolerance but are gradually lost with age. The existence of thymic epithelial progenitors (TEPCs) in the postnatal thymus has been inferred, but their identity has remained ...
Kahlia Wong +9 more
doaj +1 more source
Construction of a serum diagnostic signature based on m5C-related miRNAs for cancer detection
Frontiers in Endocrinology, 2023 Currently, no clinically relevant non-invasive biomarkers are available for screening of multiple cancer types. In this study, we developed a serum diagnostic signature based on 5-methylcytosine (m5C)-related miRNAs (m5C-miRNAs) for multiple-cancer ...
Fuzhou Tang +7 more
doaj +1 more source
Vaccines, 2023 The administration of mRNA-based tumour vaccines is considered a promising strategy in tumour immunotherapy, although its application against kidney renal clear cell carcinoma (KIRC) is still at its infancy stage.
Shichao Zhang +7 more
doaj +1 more source
TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain [PDF]
, 2016 Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system.
A Boivin +53 more
core +2 more sources
Tissue-Resident Immune Cells in Humans.
Annual Review of Immunology, 2022 Tissue-resident immune cells span both myeloid and lymphoid cell lineages, have been found in multiple human tissues, and play integral roles at all stages of the immune response, from maintaining homeostasis to responding to infectious challenges to ...
Joshua I. Gray, D. Farber
semanticscholar +1 more source
Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]
, 2019 The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David +8 more
core +4 more sources
Cytokine-Mediated Crosstalk between Immune Cells and Epithelial Cells in the Gut
Cells, 2021 Cytokines are small proteins that are secreted by a vast majority of cell types in the gut. They not only establish cell-to-cell interactions and facilitate cellular signaling, but also regulate both innate and adaptive immune responses, thereby playing ...
Mousumi Mahapatro, L. Erkert, C. Becker
semanticscholar +1 more source