Results 31 to 40 of about 443 (202)
Intestinal DC in migrational imprinting of immune cells
Immunology & Cell Biology, 2013 Dendritic cells (DCs) have a pivotal role in instructing antigen‐specific immune responses, processing and presenting antigens to CD4+ and CD8+ T cells and producing factors capable to modulate the quality of T‐cell responses. In this review, we will provide an historic overview on the identification of the mechanisms controlling lymphocyte migration ...
Stock, A, Napolitani, G, Cerundolo, V
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Hip Fracture Leads to Transitory Immune Imprint in Older Patients [PDF]
Frontiers in Immunology, 2020 Background: Hip fracture (HF) is common in the geriatric population and is associated with a poor vital and functional prognosis which could be impacted by immunological changes. The objective here is to decipher immune changes occurring in the 1st days following HF and determine how phenotype, function, and regulation of innate and adaptive ...
Héléne Vallet +12 more
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PLoS Pathogens, 2019 Across decades of co-circulation in humans, influenza A subtypes H1N1 and H3N2 have caused seasonal epidemics characterized by different age distributions of cases and mortality.
Katelyn M Gostic +5 more
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Reprogramming of the Immune System by Stress and Faulty Hormonal Imprinting [PDF]
Clinical Therapeutics, 2020 Hormonal imprinting is taking place perinatally at the first encounter between the developing hormone receptors and their target hormones. However, in this crucial period when the developmental window for physiological imprinting is open, other molecules, such as synthetic hormones and endocrine disruptors can bind to the receptors, leading to faulty ...
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VirusesThe inherent genomic plasticity of RNA viruses, particularly influenza viruses and SARS-CoV-2, poses a major obstacle to the establishment of durable herd immunity.
Siyu Lin +4 more
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Preterm Birth Affects the Risk of Developing Immune-Mediated Diseases
Frontiers in Immunology, 2017 Prematurity affects approximately 10% of all children, resulting in drastically altered antigen exposure due to premature confrontation with microbes, nutritional antigens, and other environmental factors.
Sybelle Goedicke-Fritz +6 more
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B-1 Cells Carry the Memory of Neonatal Immune Imprinting [PDF]
Immunity, 2020 Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their ...
Stefano, Vergani, Joan, Yuan
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Frontiers in Cell and Developmental Biology, 2023 PEG10 and PEG11/RTL1 are paternally expressed, imprinted genes that play essential roles in the current eutherian developmental system and are therefore associated with developmental abnormalities caused by aberrant genomic imprinting.
Hirosuke Shiura +3 more
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Immunological imprinting of humoral immunity to SARS-CoV-2 in children
Nature Communications, 2022 Abstract Omicron variants of SARS-CoV-2 are globally dominant and infection rates are very high in children. We determined immune responses following Omicron BA.1/2 infection in children aged 6-14 years and related this to prior and subsequent SARS-CoV-2 infection or vaccination.
Alexander C. Dowell +29 more
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Folia Medica, 2014 Autism is a vexed problem today. Overall, there is a high frequency of birth children (1:80 – 1:150) with late diagnosed autism spectrum disorders (ASD) and this trend is getting progressively stronger. The causes for the currently increased frequency of
Poletaev Alexander B. +5 more
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