BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan+13 more
wiley +1 more source
Transposable Element Exprssion in Tumors is Associated with Immune Infiltration and Increased Antigenicity [PDF]
Yu Kong+13 more
openalex +1 more source
Comprehensive analysis of TRIM56's prognostic value and immune infiltration in Pan-Cancer. [PDF]
Cao Y+9 more
europepmc +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
P1797Calcium/calmodulin-dependent protein kinase II (CaMKII) initiates inflammation, inflammasome activation and immune cell infiltration in response to pressure overload through signaling in cardiomyocyte [PDF]
Takeshi Suetomi+3 more
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Deciphering the Molecular Crosstalk of Endoplasmic Reticulum Stress and Immune Infiltration in Endometriosis. [PDF]
Ma Y, Ha C, Li R, Zhang R, Li M.
europepmc +1 more source
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang+9 more
wiley +1 more source
Background: Pulpitis is a significant dental concern characterized by inflammation of the dental pulp, often causing severe pain and potential tooth loss.
Xiaolan Guo+7 more
doaj
Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors [PDF]
Deborah Ayeni+16 more
openalex +1 more source