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A multiplexed view of immune infiltration
Nature Reviews Cancer, 2018Keren et al. have used multiplexed imaging in intact samples from breast cancer patients to gain insights into the architecture of the tumour immune microenvironment.
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A Study on Immune Cell Infiltration in Lung Adenocarcinoma
Combinatorial Chemistry & High Throughput Screening, 2022Background: As a vital part of the tumor environment, immune cells affect the progression of tumors, and their composition and role vary in different types of tumors and influence prognosis. These immune cells have the potential to be beneficially targeted for immunotherapy, or, conversely, they may react negatively, even leading to drug resistance ...
Hongwen Zhao, Bingqing Sun
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Classification of the Immune Composition in the Tumor Infiltrate
2019Flow cytometry is one of the most suitable techniques for analyzing and classifying different cell suspensions derived from blood or others compartments. The characterization of all different cellular subtypes is made with different antibodies that detect surface or intracytoplasmic antigens.
Davide, Brusa, Jean-Luc, Balligand
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Variability in immune infiltrates and HLA expression in cholangiocarcinoma.
Journal of Clinical Oncology, 2014230 Background: Cholangiocarcinoma continues to have a dismal prognosis. The lack of effective therapy prompted us to determine whether patients develop an immune response against their own tumors. The aim of this study is to evaluate the CD8 infiltrate and expression of HLA class I antigen processing machinery (APM) components in cholangiocarcinoma.
Sabbatino, Francesco +11 more
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Tumor infiltrating immune cells in gliomas and meningiomas
Brain, Behavior, and Immunity, 2016Tumor-infiltrating immune cells are part of a complex microenvironment that promotes and/or regulates tumor development and growth. Depending on the type of cells and their functional interactions, immune cells may play a key role in suppressing the tumor or in providing support for tumor growth, with relevant effects on patient behavior.
Domingues, Patrícia +11 more
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Decidual Immune Cell Infiltrate in Hydatidiform Mole
Cancer Investigation, 2009Hydatidiform mole is a gestational trophoblastic disease characterized by proliferation of the pregnancy-associated trophoblastic tissue. Complete hydatidiform mole is an entirely paternally derived lesion, and therefore, represents complete intrauterine allografts that can induce an altered maternal immune response Hypothesis: Here, we hypothesize ...
Mahmoud R, Hussein +3 more
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Landscape of Immune Microenvironment Under Immune Cell Infiltration Pattern in Breast Cancer
Frontiers in Immunology, 2021Shaohuai Chen
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Female Gender Predicts Augmented Immune Infiltration in Lung Adenocarcinoma
Clinical Lung Cancer, 2021J Jack Lee +2 more
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