Results 261 to 270 of about 668,593 (306)

Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma. [PDF]

Front Immunol
Zhang Z, Fan R, Ma J, Li D, Jiang Y, Liu F, Gong Q.   +6 more
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

EIF3M as a pan-cancer biomarker: prognostic significance and immune infiltration association. [PDF]

Front Mol Biosci
Zhao Z, Chen J, Cui Y, Fu Z, Deng D, Zhang X.   +5 more
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Identification of TSEN15 as a novel biomarker for diagnosis, prognosis, and immune infiltration in hepatocellular carcinoma. [PDF]

Sci Rep
Yu L, Chen D, Xu J, Zhou X, Shi N, Liu Z, Liu Y, Yu Y.   +7 more
europepmc   +1 more source

Fat-produced adipsin regulates inflammatory arthritis [PDF]

, 2019
Atkinson, John P, Brestoff, Jonathan R, Harris, Charles A, Li, Yongjia, Rohatgi, Nidhi, Teitelbaum, Steven L, Wu, Xiaobo, Zou, Wei   +7 more
core   +1 more source

Identification of anoikis-related genes and immune infiltration characteristics in Sjögren's syndrome based on machine learning. [PDF]

Front Med (Lausanne)
Wang L, Zhou Z, Zhou X, Liu Y, Wang M.
europepmc   +1 more source

HPV status determines prognostic gene expression methylation and immune infiltration in head and neck squamous cell carcinoma. [PDF]

Discov Oncol
Yang Y, Wang L, Wang R, Li H, Zhu S, Fang J, Feng L.   +6 more
europepmc   +1 more source

Identification of Ferroptosis-Related Hub Genes and Immune Infiltration Landscape in Chronic Kidney Disease via Bioinformatics and Experimental Verification. [PDF]

Immun Inflamm Dis
Luo Y, Huang ZY, Yang JF.
europepmc   +1 more source