Results 91 to 100 of about 465,229 (318)
DataSheet1_Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma.PDF [PDF]
, 2022 Introduction: Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the immune status for prognostic ...
Wenshuo Zhang (164908) +5 more
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Frontiers in Pharmacology, 2022 Amlodipine is a Ca2+ channel blocker commonly used to cardiovascular diseases such as hypertension and angina; however, its anticancer effects in lung cancer A549 cells remain unknown. In the present study, we explored the antitumor effects and molecular
Bingjie Fu +9 more
doaj +1 more source
The Aryl Hydrocarbon Receptor: Impact on the Tumor Immune Microenvironment and Modulation as a Potential Therapy [PDF]
The aryl hydrocarbon receptor (AhR) is a ubiquitous nuclear receptor with a broad range of functions, both in tumor cells and immune cells within the tumor microenvironment (TME).
Brian D. Griffith, Timothy L. Frankel
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Mapping the BCSC-1 interactome in breast cancer
Scientific ReportsBCSC-1 (breast cancer suppressor candidate-1), the official gene symbol VWA5A (von Willebrand factor A domain containing 5 A), is downregulated in a variety of cancer types including breast cancer.
Yuan Ma +10 more
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MicroorganismsThe treatment of intracellular bacterial infections such as Chlamydia remains a significant clinical challenge due to rising antibiotic resistance and persistent, immunopathology-driven tissue damage.
Shuaini Yang +9 more
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Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice
Nature Communications, 2020 The use of tumour exosome-activated dendritic cell (DC) immunotherapy shows promise for the treatment of large established tumours. Here, the authors generate alarmin HMGN1-attached tumour exosomes which significantly improve therapy efficacy by boosting
Bingfeng Zuo +13 more
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Frontiers in Immunology, 2020 Increasing evidence has revealed that the initiation and progression of breast cancer are greatly affected by the immune environment. Neutrophils are the most abundant leucocytes in circulation and act as the spearhead in inflammation, including in ...
Wei Zhang +13 more
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RhoB affects colitis through modulating cell signaling and intestinal microbiome
Microbiome, 2022 Background The pathogenesis of inflammatory bowel diseases (IBD) is multifactorial, and diagnostic and treatment strategies for IBD remain to be developed. RhoB regulates multiple cell functions; however, its role in colitis is unexplored.
Jianming Yang +12 more
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Tumor Immune Microenvironment Biomarkers for Recurrence Prediction in Locally Advanced Rectal Cancer Patients after Neoadjuvant Chemoradiotherapy [PDF]
Background/Objectives: The tumor microenvironment (TME) has emerged as a significant prognostic factor. This study aimed to identify prognostic factors by combining clinicopathologic parameters and the TME biomarkers in patients who underwent surgery ...
Cho, Sang-Hee +23 more
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Mycosis Fungoides and Sézary Syndrome: Microenvironment and Cancer Progression [PDF]
, 2023 Mycosis fungoides and Sézary syndrome are epidermotropic cutaneous lymphomas, and both of them are rare diseases. Mycosis fungoides is the most frequent primary cutaneous lymphoma.
Gabor Dobos +2 more
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