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Immune modulation in corneal transplantation

Transplantation Reviews, 2008
Allograft rejection is the most common reason for corneal transplant failure, despite the immunologic privilege of both the graft and the anterior chamber. To prevent corneal allograft rejection, various immunomodulatory strategies have been used in experimental corneal transplantation.
Hongmei, Fu   +2 more
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Immune Modulation with Interleukin‐21

Annals of the New York Academy of Sciences, 2009
Interleukin 21 (IL‐21) is produced by activated CD4+ T cells. The IL‐21R shares the common receptor gamma‐chain with IL‐2, IL‐4, IL‐7, IL‐9, and IL‐15, is widely expressed on immune cells, and mediates a variety of effects on the immune system. IL‐21 enhances the proliferation, antigen‐induced activation, clonal expansion, IFN‐γ production, and ...
Neela S, Bhave, William E, Carson
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Immune Modulating Agents

2020
Immunomodulation The Immune System and Immune Modulation, Francois Hirsch and Guido Kroemer Molecular Mechanisms Controlling Immunoglobulin E Responses, Rachel L. Miller and Paul B. Rothman Idiotypes and T Cell Selection, Bjarne Bogen, Zlatko Dembic, and Siegfried Weiss In Vivo Modulation of Lymphohemopoietic Stem Cell Populations with Cytokines ...
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Neural modulation of immune function

Journal of Neuroimmunology, 1985
In this report we review our hypotheses and approaches to the study of the relationship between the central nervous and immune systems. Discussed are results pertaining to the modulation of immune parameters resulting from perturbations of the brain employing electrolytic lesions and the neuroleptic 6-hydroxydopamine. Experiments describing the central
T L, Roszman, W H, Brooks
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Fungal-Derived Immune Modulating Molecules

2009
Invasive fungal infections are an increasing clinical problem for which new therapeutic approaches are needed. Understanding the initial interaction between fungi and the host offers potential for development of new drugs or vaccines. It has recently been recognized that like other pathogens, fungi initially interact with the innate immune system via ...
Tania C, Sorrell, Sharon C A, Chen
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Perioperative immune modulation.

Surgery, 1993
The effects of operative trauma on systemic immunity were studied. The relative effects of skin incision and of breaching the peritoneum were determined. In addition, the role of the antiendotoxic agent taurolidine in preventing postoperative immune suppression was assessed.Systemic immune responsiveness was measured as the delayed-type ...
D, Little   +3 more
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Recent Advances in Immune Modulation

Current Gene Therapy, 2007
Successful gene therapy protocols rely on the hypo-responsiveness of the immune system to transgene products generated from gene transfer vectors. In order to prevent cytotoxic lymphocyte or antibody formation induced by transgene expression, various strategies derived from recent advances in immune tolerance induction protocols have been tested in ...
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Helminths and Mucosal Immune Modulation

Annals of the New York Academy of Sciences, 2006
Abstract:  Geographic and ethnic variations in ulcerative colitis and Crohn's disease frequency suggest that environmental factors affect disease risk. Prevention of parasitic worms (helminths) through improved hygiene may be one factor leading to the increased disease prevalence. Helminths alter host mucosal and systemic immunity.
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Neuropeptides as native immune modulators

1995
Historically, all diseases in man have been considered to be interdependently related to such parameters as mental attitudes (neural factors), resistance to natural environment (immune factors), and population predisposition (genetic factors). Also, it has long been known that there are nervous system diseases that are mediated by the immune system but
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