Results 181 to 190 of about 1,217,623 (290)

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Programmable Antigen-Specific Immunity via Self-Adjuvanting Nanovaccines Co-Delivering Immune Modulators. [PDF]

Angew Chem Int Ed Engl
Ito K, Manabe Y, Ohshima S, Maeki M, Tokeshi M, Inaba H, Matsuura K, Kabayama K, Kametani Y, Fukase K.   +9 more
europepmc   +1 more source

Serum immune modulators associated with immune-related toxicities and efficacy of atezolizumab in patients with non-small cell lung cancer. [PDF]

J Cancer Res Clin Oncol, 2023
Inoue Y, Inui N, Karayama M, Asada K, Matsuura S, Ikeda M, Uto T, Fujii M, Hashimoto D, Matsui T, Matsuda H, Inami N, Toyoshima M, Kaida Y, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Suda T.   +20 more
europepmc   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Multi-omics data mining combined with experimental validation reveals ferroptosis- and autophagy-associated hub genes as diagnostic candidates and immune modulators in atherosclerosis. [PDF]

Animal Model Exp Med
Zheng X, Zheng J, Li X, Chen H, Zhang L, Zhao Y, Ling Y.   +6 more
europepmc   +1 more source

Optimal treatment sequence for targeted immune modulators for the treatment of moderate to severe ulcerative colitis. [PDF]

J Manag Care Spec Pharm, 2021
Bloudek LM, Pandey R, Fazioli K, Ollendorf DA, Carlson JJ.   +4 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Identification of palmitoylation-related lncRNAs as prognostic biomarkers and immune modulators in HCC. [PDF]

Discov Oncol
Zou Y, Zhao X, Yang S, Liu Y, Zhang S, Xu X, Chen G, Zhang Y.   +7 more
europepmc   +1 more source

Novel Immune Modulators Enhance Caenorhabditis elegans Resistance to Multiple Pathogens. [PDF]

mSphere, 2021
Hummell NA, Revtovich AV, Kirienko NV.
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source