Results 1 to 10 of about 23,444 (214)

Expanding the offer of Vaccinology Education with the Master of Science in Immunology and Vaccinology

open access: yesHuman Vaccines and Immunotherapeutics
The COVID-19 pandemic revealed the urgency for well-trained professionals in vaccinology. With the purpose of building capacity in the field, the Catholic University of Portugal created the Masters in Immunology and Vaccinology.
Paulo Bettencourt
exaly   +6 more sources

Advances of Reverse Vaccinology for mRNA Vaccine Design against SARS-CoV-2: A Review of Methods and Tools

open access: yesViruses, 2023
mRNA vaccines are a new class of vaccine that can induce potent and specific immune responses against various pathogens. However, the design of mRNA vaccines requires the identification and optimization of suitable antigens, which can be challenging and ...
Shahina Akter   +2 more
exaly   +4 more sources

From empirical vaccinology to predictive systems-based vaccine design: multi-omics integration, artificial intelligence, and global equity challenges [PDF]

open access: yesFrontiers in Systems Biology
Although vaccination remains one of the most impactful interventions in contemporary public health, with consistent and widely documented reductions in morbidity and mortality, the traditional empirical development of vaccines—largely based on trial-and ...
Nicole Simone De Lima Coelho   +1 more
doaj   +2 more sources

A Comparative Review of Veterinary and Human Vaccine Development Strategies: Insights into Herpesvirus Vaccinology from Latency to Elimination [PDF]

open access: yesVaccines
Background: Members of the virus family Herpesviridae are among the most successful pathogen groups in evolutionary history. They not only pose a serious public health threat to humans but also cause significant economic losses in the global livestock ...
Guangyi Liu   +4 more
doaj   +2 more sources

Developing vaccinology expertise for Africa: fifteen years and counting

open access: yesThe Pan African Medical Journal, 2021
For 15 years, the Annual African Vaccinology Course (AAVC) hosted by the Vaccines for Africa Initiative, has been at the forefront of vaccinology training in Africa.
Edina Amponsah-Dacosta   +5 more
doaj   +1 more source

Repurposing drugs: Lessons from rheumatology in the COVID-19 pandemic

open access: yesIndian Journal of Rheumatology, 2021
Humanity currently faces one of its biggest challenges, created by a tiny quasi-life form, the severe acute respiratory syndrome coronavirus 2. The rapidity of spread and the enormous burden placed on public health infrastructure by the coronavirus ...
Manesh Manoj   +4 more
doaj   +1 more source

Tick-borne encephalitis virus (TBEV), is the disease still dangerous?

open access: yesJournal of Education, Health and Sport, 2022
Tick-borne encephalitis virus (TBEV)  belongs to the family Flaviviridae. Flaviviruses are 50 nm viruses having a membrane envelope with an RNA genome. The vector of TBEV is the common tick (Ixodes ricinus) prevalent mainly in Europe.
Karolina Rogulska   +5 more
doaj   +1 more source

VPAgs-Dataset4ML: A Dataset to Predict Viral Protective Antigens for Machine Learning-Based Reverse Vaccinology

open access: yesData, 2023
Reverse vaccinology (RV) is a computer-aided approach for vaccine development that identifies a subset of pathogen proteins as protective antigens (PAgs) or potential vaccine candidates. Machine learning (ML)-based RV is promising, but requires a dataset
Zakia Salod, Ozayr Mahomed
doaj   +1 more source

Production and purification of high-titer OrfV for preclinical studies in vaccinology and cancer therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Poxviruses have been used extensively as vaccine vectors for human and veterinary medicine and have recently entered the clinical realm as immunotherapies for cancer.
Jacob P. van Vloten   +8 more
doaj   +1 more source

PanRV: Pangenome-reverse vaccinology approach for identifications of potential vaccine candidates in microbial pangenome

open access: yesBMC Bioinformatics, 2019
Background A revolutionary diversion from classical vaccinology to reverse vaccinology approach has been observed in the last decade. The ever-increasing genomic and proteomic data has greatly facilitated the vaccine designing and development process ...
Kanwal Naz   +6 more
doaj   +1 more source

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