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British Medical Bulletin, 1991
The concept that the immune system is involved in defence against cancer goes back nearly a hundred years. Despite increased sophistication in our analysis of the immune response it has proven difficult to demonstrate a powerful role of the immune system in either the prevention or treatment of cancer.
K, Sikora, N, James
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The concept that the immune system is involved in defence against cancer goes back nearly a hundred years. Despite increased sophistication in our analysis of the immune response it has proven difficult to demonstrate a powerful role of the immune system in either the prevention or treatment of cancer.
K, Sikora, N, James
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Immune Modulation by Flaviviruses
2003Flaviviruses cause pleomorphic disease with significant morbidity and mortality worldwide. Interestingly, in contrast to most viruses, which subvert or avoid host immune systems, members of the neurotropic Japanese encephalitis serocomplex cause functional changes associated with increased efficacy of the immune response. These viruses induce increased
Nicholas J, King +2 more
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Immune modulation by butyrophilins
Nature Reviews Immunology, 2014The B7 family of co-stimulatory molecules has an important role in driving the activation and inhibition of immune cells. Evolving data have shown that a related family of molecules - the butyrophilins - have similar immunomodulatory functions to B7 family members and may represent a novel subset of co-stimulatory molecules.
Heather A, Arnett, Joanne L, Viney
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Radiation as an Immune Modulator
Seminars in Radiation Oncology, 2013Radiation therapy is currently one of the most widely utilized treatment strategies in the clinical management of cancer. Classically, radiation therapy was developed as an anticancer treatment on the basis of its capacity to induce DNA double strand breaks in exposed cancer cells, ultimately resulting in tumor cell death.
Byron, Burnette, Ralph R, Weichselbaum
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Prostaglandins as modulators of immunity
Trends in Immunology, 2002Prostaglandins are potent lipid molecules that affect key aspects of immunity. The original view of prostaglandins was that they were simply immunoinhibitory. This review focuses on recent findings concerning prostaglandin E2 (PGE2) and the PGD2 metabolite 15-deoxy-Delta(12,14)-PGJ2, and their divergent roles in immune regulation. We will highlight how
Sarah G, Harris +4 more
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Acupuncture and immune modulation
Autonomic Neuroscience, 2010Acupuncture is probably the most popular alternative therapy practiced in the United States, Europe and many Asian countries. It has been applied clinically for more than 5 thousand years according to the ancient oriental medical theory. A great deal of acupuncture research has been achieved, with particular efforts toward understanding the pain ...
Sun Kwang, Kim, Hyunsu, Bae
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Modulating the immune response to genetic immunization
The FASEB Journal, 1998ABSTRACT Genetic immunization, also known as DNA or polynucleotide immunization, is a novel strategy for vaccine development in which plasmid DNA encoding either individual or a collection of antigens is directly administered to a host.
A D, Cohen, J D, Boyer, D B, Weiner
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Immune modulation: the genetic approach
Veterinary Immunology and Immunopathology, 2002As part of a comprehensive strategy to combat diseases, improving genetically resistance to diseases and therefore immune capacities of animals is more and more desirable. However, research is still needed to develop genetic tools that may be used. In this search, lines selected for various immune responses are used to study relevant immune markers ...
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Immunity to gastrointestinal nematodes: a story of immune modulation
Expert Review of Clinical Immunology, 2005Infections with gastrointestinal nematodes are some of the most prevalent infections in the world today. Despite the fact that antihelminthic drugs are generally regarded as safe, efficient and are widely available, the level of infection remains as high or, in some cases, even higher than 50 years ago.
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Modulation of Immune Responses by Nanoparticles
Nanomedicine, 2021Christina Janko +5 more
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