Results 171 to 180 of about 128,938 (315)

Tuberculosis-immune reconstitution inflammatory syndrome

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016
Tuberculosis-immune reconstitution inflammatory syndrome is an excessive immune response against Mycobacterium tuberculosis that may occur in either HIV-infected or uninfected patients, during or after completion of anti-TB therapy.
Massimiliano Lanzafame, Sandro Vento
doaj  

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

Advanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu   +8 more
wiley   +1 more source

HIV dynamics and natural history studies: Joint modeling with doubly interval-censored event time and infrequent longitudinal data

, 2011
Hepatitis C virus (HCV) coinfection has become one of the most challenging clinical situations to manage in HIV-infected patients. Recently the effect of HCV coinfection on HIV dynamics following initiation of highly active antiretroviral therapy (HAART)
Hogan, Joseph W., Su, Li
core   +1 more source

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Combining Cryogel Architecture and Macromolecular Crowding‐Enhanced Extracellular Matrix Cues to Mimic the Bone Marrow Niche

Macromolecular Chemistry and Physics, Volume 224, Issue 1, January 2023., 2023
The development of a bone marrow niche model that closely mimics the natural 3D architecture of trabecular bone and the extracellular stromal compartment is reported. Macroporous cryogel scaffolds are functionalized with tissue‐specific, cell‐secreted ECM biopolymers. Macromolecular crowders enhance both ECM production and altered the microstructure of
Laura Martínez‐Vidal, Valentina Magno, Petra B. Welzel, Jens Friedrichs, Martin Bornhäuser, Carsten Werner   +5 more
wiley   +1 more source

Immune electron microscopic localization of dinitrophenyl-modified ribosomal protein S19 in reconstituted Escherichia coli 30 S subunits using antibodies to dinitrophenol.

, 1988
H M Olson, T.V. Olah, Barry S. Cooperman, Dohn G. Glitz   +3 more
openalex   +1 more source

Immune reconstitution after allogeneic marrow transplantation compared with blood stem cell transplantation [PDF]

, 2001
Jan Storek, Monja A. Dawson, Barry E. Storer, Terry Stevens-Ayers, David G. Maloney, Kieren A. Marr, Robert P. Witherspoon, William Bensinger, Mary E.D. Flowers, Paul J. Martin, Rainer Storb, Frederick R. Appelbaum, Michael Boeckh   +12 more
openalex   +1 more source

Fluorescence Color Gradient Immunochromatographic Assay for Highly‐Sensitive, Quantitative, and Simultaneous Detection of Small‐Molecule Pollutants

Aggregate, EarlyView.
This article reports on a universal fluorescence color gradient immunochromatographic assay (FCGICA) technology based on the superposition of red and green fluorescence dual signals, which enables ultra‐sensitive, wide‐range, and simultaneous quantitative detection of multiple small molecules in complex samples.
Shu Wang, Changyue Xu, Xiaosong Wu, Tao Zhang, Jiahuan Zhang, Wenlong Bai, Shuai Zheng, Bing Gu, Chongwen Wang   +8 more
wiley   +1 more source

Immunologic reconstitution by immune organ transplantation in immunodeficiency disease

, 1983
Shuzo Matsumoto, Yukio Sakiyama, H. Tsuneta, Yutaka Takahashi   +3 more
openalex   +2 more sources