Analysis of immune reconstitution in children undergoing cord blood transplantation [PDF]
Antonia Moretta+11 more
openalex +1 more source
Immune Reconstitution in HIV-Infected Patients [PDF]
The prognosis of patients infected with human immunodeficiency virus (HIV) type 1 has dramatically improved since the advent of potent antiretroviral therapies (ARTs), which have enabled sustained suppression of HIV replication and recovery of CD4 T cell
Battegay, Manuel+5 more
core
Recurrences of Cytomegalovirus Retinitis in a Human Immunodeficiency Virus-Infected Patient, Despite Potent Antiretroviral Therapy and Apparent Immune Reconstitution [PDF]
Steven C. Johnson+3 more
openalex +1 more source
Background Immune reconstitution following the initiation of combination antiretroviral therapy (cART) significantly impacts the prognosis of individuals infected with human immunodeficiency virus (HIV).
Funsho J. Ogunshola+2 more
doaj +1 more source
Proliferative Responses to Human Immunodeficiency Virus Type 1 (HIV‐1) Antigens in HIV‐1–Infected Patients with Immune Reconstitution [PDF]
Joel N. Blankson+2 more
openalex +1 more source
Clonal Hematopoiesis and Thrombosis
ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
wiley +1 more source
Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
wiley +1 more source
Immune Reconstitution Prevents Continuous Equine Infectious Anemia Virus Replication in an Arabian Foal with Severe Combined Immunodeficiency: Lessons for Control of Lentiviruses [PDF]
Robert H. Mealey+4 more
openalex +1 more source
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro+16 more
wiley +1 more source
Inhibition of signaling downstream of beta‐2 adrenoceptor by propranolol in prostate cancer cells
Abstract Background There is accumulating evidence that propranolol, an antagonist of beta‐1 and beta‐2 adrenoreceptors, extends survival of patients with prostate cancer; yet it is not known whether propranolol inhibits beta‐adrenergic signaling in prostate cancer cells, or systemic effects of propranolol play the leading role in slowing down cancer ...
Aljoharah Alaskar+7 more
wiley +1 more source