Results 11 to 20 of about 75,329 (259)

Immune reconstitution inflammatory syndrome [PDF]

open access: yesMedical Journal Armed Forces India, 2015
Immune reconstitution inflammatory syndrome (IRIS) is defined as occurrence or worsening of clinical and/or laboratory parameters despite a favorable outcome in human immunodeficiency virus (HIV) surrogate markers.1 It has been described in 5%–10% of HIV seropositive patients with CD4+ T-cell count less than 200/μLand occurs most commonly with ...
M S, Barthwal   +5 more
openaire   +2 more sources

The Epic Race to Immune Reconstitution [PDF]

open access: yesBiology of Blood and Marrow Transplantation, 2012
Regardless of the hematopoietic stem cell (HSC) source, reconstitution of adaptive immunity is arguably the last great barrier to successful allogeneic hematopoietic cell transplantation. Early after transplantation, prolonged lymphocytopenia, and profound immune dysfunction result in infectious complications that are frequent and often life ...
Verneris, Michael, Wagner, John E.
openaire   +2 more sources

Immune Reconstitution Inflammatory Syndrome [PDF]

open access: yesRespiratory Care, 2014
Immune reconstitution inflammatory syndrome (IRIS) is a collection of inflammatory disorders associated with paradoxical worsening of preexisting infectious processes after the initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected individuals ...
Chang-Han, Lo, Te-Yu, Lin
openaire   +4 more sources

Comparison of immune reconstitution after allogeneic vs. autologous stem cell transplantation in 182 pediatric recipients

open access: yesPediatric Hematology Oncology Journal, 2017
Background: Hematopoietic stem cell transplantation (HSCT) is a life-saving procedure for children with a variety of malignant and non-malignant conditions. However, even if immune reconstitution after HSCT has been studied in extensively, until now data
V. Wiegering   +3 more
doaj   +1 more source

Subdividing ART patients and analyzing the medical burden by modeling of CD4 cell count

open access: yesJournal of Family Medicine and Primary Care, 2023
Objective: To subdivide the antiretroviral therapy (ART) human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) patients by modeling the CD4 cell count variable, with an aim to reduce the medical burden from lifelong ART. Materials
Li Min, Wang Qunwei
doaj   +1 more source

Thymic involution and immune reconstitution [PDF]

open access: yesTrends in Immunology, 2009
Chronic thymus involution associated with aging results in less efficient T-cell development and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is linked to increased morbidity and mortality in a wide range of clinical settings.
Heather E, Lynch   +5 more
openaire   +2 more sources

Immune reconstitution after hematopoietic stem cell transplantation

open access: yesFrontiers in Immunology, 2016
The reconstitution and the regaining of function of a healthy, transplanted immune system is of utmost importance for the recovery and long term survival of patients after HSCT.
Justyna Ogonek   +6 more
doaj   +1 more source

Rapid CD4 decline prior to antiretroviral therapy predicts subsequent failure to reconstitute despite HIV viral suppression

open access: yesJournal of Infection and Public Health, 2018
HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts.
Majid Darraj   +4 more
doaj   +1 more source

Severe leukoencephalopathy with fulminant cerebral edema reflecting immune reconstitution inflammatory syndrome during HIV infection: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Immune reconstitution inflammatory syndrome is a well-known complication in HIV-infected patients after initiation of highly active antiretroviral therapy resulting in rapid CD4+ cell count recovery and suppression of viral load.
Niederstadt Thomas   +6 more
doaj   +1 more source

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

open access: yesBlood Advances, 2018
: Immune reconstitution following hematopoietic stem cell transplantation (HSCT) is critical in preventing harmful sequelae in recipients with cytomegalovirus (CMV) infection.
Kristine Hardy   +10 more
doaj   +1 more source

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