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Immune reconstitution inflammatory syndrome in treatment-experienced HIV-infected patients
Clinical and Biomedical Research, 2014 We described two cases of treatment-experienced HIV-infected patients who presented with cytomegalovirus uveitis and Cryptococcus neoformans adenitis as a manifestation of immune reconstitution inflammatory syndrome (IRIS) during salvage treatment ...
Fabiano Ramos +2 more
doaj +3 more sources
Indian Journal of Dermatology, 2006 Immune reconstitution inflammatory syndrome describes a collection of inflammatory disorders associated with paradoxical deterioration of various pre-existing processes following start of highly active antiretroviral therapy (HAART) in human ...
Mukhopadhyay Partha +4 more
doaj +1 more source
Immune reconstitution inflammatory syndrome [PDF]
Medical Journal Armed Forces India, 2015 Immune reconstitution inflammatory syndrome (IRIS) is defined as occurrence or worsening of clinical and/or laboratory parameters despite a favorable outcome in human immunodeficiency virus (HIV) surrogate markers.1 It has been described in 5%–10% of HIV seropositive patients with CD4+ T-cell count less than 200/μLand occurs most commonly with ...
M S, Barthwal +5 more
openaire +2 more sources
The Epic Race to Immune Reconstitution [PDF]
Biology of Blood and Marrow Transplantation, 2012 Regardless of the hematopoietic stem cell (HSC) source, reconstitution of adaptive immunity is arguably the last great barrier to successful allogeneic hematopoietic cell transplantation. Early after transplantation, prolonged lymphocytopenia, and profound immune dysfunction result in infectious complications that are frequent and often life ...
Verneris, Michael, Wagner, John E.
openaire +2 more sources
Immune Reconstitution Inflammatory Syndrome [PDF]
Respiratory Care, 2014 Immune reconstitution inflammatory syndrome (IRIS) is a collection of inflammatory disorders associated with paradoxical worsening of preexisting infectious processes after the initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV)-infected individuals ...
Chang-Han, Lo, Te-Yu, Lin
openaire +4 more sources
Thymic involution and immune reconstitution [PDF]
Trends in Immunology, 2009 Chronic thymus involution associated with aging results in less efficient T-cell development and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is linked to increased morbidity and mortality in a wide range of clinical settings.
Heather E, Lynch +5 more
openaire +2 more sources
Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]
, 2013 Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Ollerton, Jeff, Parker, William
core +1 more source
Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation [PDF]
, 2012 Background: Reconstitution of cytomegalovirus-specific CD3+CD8+ T cells (CMV-CTLs) after allogeneic hematopoietic stem cell transplantation (HSCT) is necessary to bring cytomegalovirus (CMV) reactivation under control. However, the parameters determining
Matthias Eder (21135) +74 more
core +2 more sources
Immunological characterization of the HIV-tuberculosis associated immune reconstitution inflammatory syndrome [PDF]
, 2011 While the integration of anti-TB and cART therapies is associated with substantial clinical improvement in the majority of patients, HIV-Tuberculosis associated Immune Reconstitution Inflammatory Syndrome (TB-IRIS) has been shown to occur in a ...
Tadokera, Rabecca
core +1 more source
Journal of Infection and Public Health, 2018 HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts.
Majid Darraj +4 more
doaj +1 more source