Results 21 to 30 of about 2,306,505 (335)

Fish Collagen Peptides Protect against Cisplatin-Induced Cytotoxicity and Oxidative Injury by Inhibiting MAPK Signaling Pathways in Mouse Thymic Epithelial Cells

Marine Drugs, 2022
Thymic epithelial cells (TECs) account for the most abundant and dominant stromal component of the thymus, where T cells mature. Oxidative- or cytotoxic-stress associated injury in TECs, a significant and common problem in many clinical settings, may ...
Won Hoon Song, Hye-Yoon Kim, Ye Seon Lim, Seon Yeong Hwang, Changyong Lee, Do Young Lee, Yuseok Moon, Yong Jung Song, Sik Yoon   +8 more
doaj   +1 more source

Infectious complications, immune reconstitution, and infection prophylaxis after CD19 chimeric antigen receptor T-cell therapy

Bone Marrow Transplantation, 2022
CD19-targeted chimeric antigen receptor (CAR) T-cell becomes a breakthrough therapy providing excellent remission rates and durable disease control for patients with relapsed/refractory (R/R) hematologic malignancies.
K. Wudhikarn, M. Perales
semanticscholar   +1 more source

Thymus aging and immune reconstitution, progresses and challenges.

Seminars in Immunology, 2023
Thymus is a primary lymphoid organ essential for the development of T lymphocytes. Age-related thymic involution is a prominent feature of immune senescence.
Yue Ru Li, J. Zúñiga-Pflücker
semanticscholar   +1 more source

Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation

Journal of Allergy and Clinical Immunology, 2017
Rick Admiraal, Coco de Koning, Caroline A Lindemans   +2 more
exaly   +2 more sources

Immune reconstitution and infectious complications following axicabtagene ciloleucel therapy for large B-cell lymphoma.

Blood Advances, 2021
Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 has significantly improved outcomes in the treatment of refractory or relapsed large B-cell lymphoma (LBCL).
John H. Baird, D. Epstein, J. Tamaresis, Zachary J Ehlinger, J. Spiegel, Juliana K. Craig, Gursharan K. Claire, M. Frank, Lori S. Muffly, P. Shiraz, E. Meyer, S. Arai, J. Brown, L. Johnston, R. Lowsky, R. Negrin, Andrew R. Rezvani, W. Weng, Theresa M. Latchford, B. Sahaf, C. Mackall, D. Miklos, S. Sidana   +22 more
semanticscholar   +1 more source

Systemic Inflammation Associated with Immune Reconstitution Inflammatory Syndrome in Persons Living with HIV

Life, 2021
Antiretroviral therapy (ART) has represented a major advancement in the care of people living with HIV (PLWHH), resulting in significant reductions in morbidity and mortality through immune reconstitution and attenuation of homeostatic disruption ...
Caian L. Vinhaes, M. Araújo-Pereira, Rafael Tibúrcio, Juan M Cubillos-Angulo, F. O. Demitto, Kevan M Akrami, B. Andrade   +6 more
semanticscholar   +1 more source

Fish Collagen Peptides Enhance Thymopoietic Gene Expression, Cell Proliferation, Thymocyte Adherence, and Cytoprotection in Thymic Epithelial Cells via Activation of the Nuclear Factor-κB Pathway, Leading to Thymus Regeneration after Cyclophosphamide-Induced Injury

Marine Drugs, 2023
Prolonged thymic involution results in decreased thymopoiesis and thymic output, leading to peripheral T-cell deficiency. Since the thymic-dependent pathway is the only means of generating fully mature T cells, the identification of strategies to enhance
Do Young Lee, Won Hoon Song, Ye Seon Lim, Changyong Lee, Lata Rajbongshi, Seon Yeong Hwang, Byoung Soo Kim, Dongjun Lee, Yong Jung Song, Hwi-Gon Kim, Sik Yoon   +10 more
doaj   +1 more source

Identifying risk factors of immune reconstitution inflammatory syndrome in AIDS patients receiving highly active anti-retroviral therapy

Brazilian Journal of Infectious Diseases, 2013
Immune reconstitution inflammation syndrome typically occurs within days after patients undergo highly active anti-retroviral therapy and is a big hurdle for effective treatment of AIDS patients.
Bo He, Yuhuang Zheng, Meng Liu, Guoqiang Zhou, Xia Chen, Diallo Mamadou, Yan He, Huaying Zhou, Zi Chen   +8 more
doaj   +3 more sources

Is immunological recovery clinically relevant at 100 days after allogeneic transplantation? [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims Immune reconstitution following allogeneic hematopoietic stem cell transplantation (HSCT) is affected by multiple variables during the transplantation.
Jin Park, Sung Hee Lim, Se Hyung Kim, Jina Yun, Chan Kyu Kim, Sang Cheol Lee, Jong Ho Won, Dae Sik Hong, Seong Kyu Park   +8 more
doaj   +1 more source

The role of pyroptosis in incomplete immune reconstitution among people living with HIV：Potential therapeutic targets

Pharmacological Research, 2023
Globally, HIV infection causes significant morbidity and mortality, and is a major public health problem. Despite the fact that widespread use of antiretroviral therapy (ART) has substantially altered the natural history of HIV infection from originally ...
Chao Xia, Xue Zhang, Vijay Harypursat, Jing Ouyang, Yaokai Chen   +4 more
doaj   +1 more source