Results 31 to 40 of about 1,305,369 (291)

Diagnosis, treatment and immunopathogenesis of the HIV-associated tuberculosis immune reconstitution inflammatory syndrome [PDF]

, 2011
The paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a frequent complication of antiretroviral therapy (ART) among patients who start ART while on treatment for tuberculosis (TB).
Meintjes, Graeme
core   +1 more source

Severe leukoencephalopathy with fulminant cerebral edema reflecting immune reconstitution inflammatory syndrome during HIV infection: a case report

Journal of Medical Case Reports, 2010
Introduction Immune reconstitution inflammatory syndrome is a well-known complication in HIV-infected patients after initiation of highly active antiretroviral therapy resulting in rapid CD4+ cell count recovery and suppression of viral load.
Niederstadt Thomas, Minnerup Jens, Reichelt Doris, Dziewas Rainer, Oelschlaeger Christian, Ringelstein Erich B, Husstedt Ingo W   +6 more
doaj   +1 more source

Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients

Blood Advances, 2018
: Immune reconstitution following hematopoietic stem cell transplantation (HSCT) is critical in preventing harmful sequelae in recipients with cytomegalovirus (CMV) infection.
Kristine Hardy, Corey Smith, Wen Juan Tu, Robert McCuaig, Archana Panikkar, Vijayendra Dasari, Fan Wu, Siok-Keen Tey, Geoffrey R. Hill, Rajiv Khanna, Sudha Rao   +10 more
doaj   +1 more source

Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant

Journal of Hematology & Oncology, 2022
Despite the increased usage of post-transplant cyclophosphamide (PTCy) in allogeneic hematopoietic stem cell transplantation (allo-HSCT), our knowledge of immune reconstitution post-allo-HSCT in the setting of PTCy is limited.
Chenchen Zhao, Matthew Bartock, Bei Jia, Neal Shah, David F. Claxton, Baldeep Wirk, Kevin L. Rakszawski, Myles S. Nickolich, Seema G. Naik, Witold B. Rybka, W Christopher C. Ehmann, Raymond J. Hohl, Jessica Valentin, Michelle Bernas-Peterson, Emily M. Gerber, Michele Zimmerman, Joseph A. Mierski, Shin Mineishi, Hong Zheng   +18 more
doaj   +1 more source

Rebooting immunity in congenital athymia: Factors impacting reconstitution with thymus implantationFactors impacting reconstitution with thymus implantation [PDF]

Journal of Human Immunity
Allogeneic processed thymus tissue-agdc (RETHYMIC) is approved therapy for treatment of congenital athymia. Study outcomes include changes in T lymphocyte subsets and T cell function.
Samantha Cresoe-Ortiz, Guglielmo Venturi, Elizabeth A. McCarthy, Benjamin Stewart-Bates, Jennifer R. Heimall, Eveline Y. Wu, John W. Sleasman, Geoffrey Hall   +7 more
doaj   +1 more source

Immune Reconstitution Inflammatory Syndrome in Non-Hiv Immunocompromised Patients

, 2011
Purpose of review In the era of highly active antiretroviral therapy, immune reconstitution inflammatory syndrome has become well recognized in the HIV-infected population. However, little is known about its occurrence in non-HIV immunocompromised hosts.
孫幸筠, Sun, Hsin-Yun; Singh, Nina
core   +1 more source

Cerebellitis associated with cryptococcal-immune reconstitution inflammatory syndrome

, 2023
Cerebellitis associated with cryptococcal immune reconstitution inflammatory syndrome (IRIS) has not been previously reported.
Eliahu Bishburg, Dennis Hogan, Madhu Suryadevara   +2 more
core   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Mass Cytometry for the Assessment of Immune Reconstitution After Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2018
Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-dimensional single-cell analysis of the immune system. It enables the simultaneous measurement of over 40 markers on individual cells through the use of monoclonal ...
Lauren Stern, Lauren Stern, Lauren Stern, Helen McGuire, Helen McGuire, Helen McGuire, Helen McGuire, Selmir Avdic, Selmir Avdic, Selmir Avdic, Simone Rizzetto, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Barbara Fazekas de St Groth, Fabio Luciani, Barry Slobedman, Barry Slobedman, Barry Slobedman, Emily Blyth, Emily Blyth, Emily Blyth, Emily Blyth   +22 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source