Results 31 to 40 of about 2,306,505 (335)
Immune reconstitution inflammatory syndrome [PDF]
Medical Journal Armed Forces India, 2015 Immune reconstitution inflammatory syndrome (IRIS) is defined as occurrence or worsening of clinical and/or laboratory parameters despite a favorable outcome in human immunodeficiency virus (HIV) surrogate markers.1 It has been described in 5%–10% of HIV seropositive patients with CD4+ T-cell count less than 200/μLand occurs most commonly with ...
M S, Barthwal +5 more
openaire +2 more sources
Journal of Leukocyte Biology, 2020 The morbidity and mortality of HIV type‐1 (HIV‐1)‐related diseases were dramatically diminished by the grounds of the introduction of potent antiretroviral therapy, which induces persistent suppression of HIV‐1 replication and gradual recovery of CD4+ T ...
Xiao-dong Yang +5 more
semanticscholar +1 more source
Haematologica, 2020 CD19 chimeric antigen receptor T (CAR T)-cell therapy with axicabtagene ciloleucel (axi-cel) for relapsed or refractory (R/R) large B-cell lymphoma (LBCL) may lead to durable remissions, however, prolonged cytopenias and infections may occur.
J. Logue +22 more
semanticscholar +1 more source
The Epic Race to Immune Reconstitution [PDF]
Biology of Blood and Marrow Transplantation, 2012 Regardless of the hematopoietic stem cell (HSC) source, reconstitution of adaptive immunity is arguably the last great barrier to successful allogeneic hematopoietic cell transplantation. Early after transplantation, prolonged lymphocytopenia, and profound immune dysfunction result in infectious complications that are frequent and often life ...
Verneris, Michael, Wagner, John E.
openaire +2 more sources
Medical Hypotheses, 2020 With the progression of the COVID-19 pandemic, there have been different reports about the development of autoimmune diseases once the infection is controlled.
C. Cañas
semanticscholar +1 more source
Immune Reconstitution Inflammatory Syndrome [PDF]
Respiratory Care, 2014 The prognosis of patients with human immunodeficiency virus (HIV) infection has dramatically improved since the advent of potent antiretroviral therapy (ART), which has enabled sustained suppression of HIV replication, recovery of CD4 Tcell counts, and a substantial decrease in the frequency of opportunistic infections (OIs) and of mortality.
Soentjens, P. H. P. +3 more
openaire +4 more sources
Subdividing ART patients and analyzing the medical burden by modeling of CD4 cell count
Journal of Family Medicine and Primary Care, 2023 Objective: To subdivide the antiretroviral therapy (ART) human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) patients by modeling the CD4 cell count variable, with an aim to reduce the medical burden from lifelong ART. Materials
Li Min, Wang Qunwei
doaj +1 more source
Immune reconstitution syndrome in HIV: validating a case definition and identifying clinical predictors in persons initiating antiretroviral therapy [PDF]
, 2006 Background: Clinical deterioration after initiation of antiretroviral therapy may result from restored immunity. There is no standard clinical definition for immune reconstitution syndrome.
Wall, Jennifer +4 more
core +1 more source
Thymic involution and immune reconstitution [PDF]
Trends in Immunology, 2009 Chronic thymus involution associated with aging results in less efficient T-cell development and decreased emigration of naïve T cells to the periphery. Thymic decline in the aged is linked to increased morbidity and mortality in a wide range of clinical settings.
Heather E, Lynch +5 more
openaire +2 more sources
Journal of Infection and Public Health, 2018 HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts.
Majid Darraj +4 more
doaj +1 more source