Results 251 to 260 of about 75,454 (300)

Immune reconstitution

Clinics in Laboratory Medicine, 2002
Immune reconstitution in HIV-infected patients remains a potential mechanism to explain delayed disease progression and increased survival following suppressive therapy. Many discrepancies remain to be studied. Is an immune response to HIV protective? Why are anti-HIV CD4 responses lost so quickly in progressors and how can they be restored?
Drew, Weissman, Luis J, Montaner
openaire   +2 more sources

Immune Reconstitution Inflammatory Syndrome

Advances in Dental Research, 2011
Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon observed in patients recovering from immunodeficiency. The clinical presentation of IRIS involves the unmasking of covert infections or the worsening of overt conditions. Several causes and pathways have been suggested, most recognizing an inflammatory flare component occurring in the ...
Alexandra Stanislavsky, Rohit Sharma, Simran Sampath Kumar   +2 more
openaire   +3 more sources

Immune reconstitution associated hypercalcemia

The American Journal of Emergency Medicine, 2009
The emergence of highly active antiretroviral therapy using combinations of reverse transcriptase and protease inhibitors ushered the dawn of a new era in management of human immunodeficiency virus infection. Immune reconstitution inflammatory syndrome is an adverse consequence of the restoration of pathogen-specific immune responses during the early ...
Yu-Tzu, Tsao, Yi-Chang, Wu, Cheng-Shu, Yang, Ying-Tsun, Lin   +3 more
openaire   +2 more sources

Cancer, Aging and Immune Reconstitution

Anti-Cancer Agents in Medicinal Chemistry, 2013
Aging is a complex phenomenon involving multiple physiological functions. Among these, very important are the modifications induced in the immune system; these modifications may be related to cancer development, a disease of older people. We herein describe the age-dependent alterations observed in the various arms of the immune system. Both innate and
Zanussi S., Serraino D., Dolcetti R., Berretta M., De Paoli P.   +4 more
openaire   +3 more sources

Immune reconstitution of acquired immune deficiency syndrome

Chinese Journal of Integrative Medicine, 2010
Acquired immune deficiency syndrome (AIDS) is a chronic infectious disease, which the patients are infected with human immunodeficiency virus (HIV). HIV damages the human's immune function and causes CD4 cell decline in the number and function. Immune reconstitution is an important treatment to AIDS.
Jie, Wang, Hong-sheng, Lin, Meng-yu, Liu, Yong, Li   +3 more
openaire   +2 more sources

Ocular immune reconstitution inflammatory syndromes

Current Opinion in HIV and AIDS, 2008
The aim of this article is to review the current literature concerning immune reconstitution inflammatory syndrome in relation to the eye. The definition, epidemiology, pathophysiology, risk factors, clinical features, diagnosis and treatment are discussed.Immune reconstitution inflammatory syndrome affecting the eye has been documented in association ...
Otiti-Sengeri, J., Meenken, C., van den Horn, G.J., Kempen, J.H.   +3 more
openaire   +4 more sources

Immune Reconstitution Inflammatory Syndrome

Emergency Medicine Clinics of North America, 2010
Immune reconstitution inflammatory syndrome (IRIS) must be considered in the differential diagnosis for any patient infected with HIV who has begun ART in the preceding months. Distinguishing between manifestations of IRIS and active infection is of paramount importance and poses a diagnostic challenge to the provider in the acute care setting ...
openaire   +2 more sources

Immune reconstitution therapy in NMOSD

Multiple Sclerosis and Related Disorders, 2021
NMO spectrum disorders [NMOSD] is a relapsing autoimmune disorder with attacks of optic neuritis (ON) and transverse myelitis (TM). A large proportion of NMOSD patients have no or a partial recovery after relapse.The neuro-immunological community now has a number of indicated agents for NMOSD therapy including eculizumab [Soliris®], inebilizumab ...
openaire   +2 more sources

Immune reconstitution in HIV infection

Current Opinion in Immunology, 1997
Progressive immune deficiency arising during HIV disease reflects the continual degradation and the ultimate deletion of immune specificites defined by the CD4(+) T lymphocyte repertoire. Recent evidence suggests that improvements in the immune function of patients with HIV who receive therapy primarily reflects the expansion of CD4(+) T lymphocyte ...
Emery, S, Lane, HC
openaire   +3 more sources

Immune reconstitution strategies in HIV

Current Infectious Disease Reports, 2001
Although potent antiretroviral therapy can dramatically decrease HIV replication and improve some aspects of host immunity, incomplete immune reconstitution persists even after several years of fully suppressive therapy. In addition, long-term toxicities of antiretroviral medications and the probability of developing multidrug-resistant virus with long-
Matthew R., Leibowitz, Ronald T., Mitsuyasu   +1 more
openaire   +2 more sources