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Immune Reconstitution Inflammatory Syndrome: Opening Pandora’s Box [PDF]

Case Reports in Infectious Diseases, 2017
One of the purposes of antiretroviral therapy (ART) is to restore the immune system. However, it can sometimes lead to an aberrant inflammatory response and paradoxical clinical worsening known as the immune reconstitution inflammatory syndrome (IRIS ...
Mariana Meireles, Conceição Souto Moura, Margarida França   +2 more
doaj   +13 more sources

Immune Reconstitution Inflammatory Syndrome in children

South African Journal of Radiology, 2017
Immune Reconstitution Inflammatory Syndrome (IRIS) refers to a collection of inflammatorydisorders, predominantly related to infectious processes that manifest after the initiation ofantiretroviral therapy (ART) and can be classified as unmasking or ...
Nasreen Mahomed, Gary Reubenson
doaj   +7 more sources

Current knowledge of the immune reconstitution inflammatory syndrome in Whipple disease: a review [PDF]

Frontiers in Immunology, 2023
Immune reconstitution inflammatory syndrome (IRIS) is characterized by exaggerated and dysregulated inflammatory responses that occur as a result of reconstitution of adaptive or innate immunity.
Xiangyi Song, Ruifeng Duan, Liwei Duan, Lijuan Wei   +3 more
doaj   +3 more sources

Dynamics of T-Lymphocyte Activation Related to Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in Persons With Advanced HIV

Frontiers in Immunology, 2021
Most persons living with HIV (PLWH) experience a significant restoration of their immunity associated with successful inhibition of viral replication after antiretroviral therapy (ART) initiation.
Rafael Tibúrcio, Beatriz Barreto‐Duarte, Gopolan Naredren, Artur T. L. Queiroz, Anbalagan Selvaraj, Kaustuv Nayak, N. Ravichandran, Rajasekaran Subramani, Lis Ribeiro do Valle Antonelli, Kumar Satagopan, Komathi Anbalagan, Brian Porter, Alan Sher, Soumya Swaminathan, Irini Sereti, Bruno B. Andrade   +15 more
openalex   +2 more sources

A Severe Case of Molluscum Contagiosum Immune Reconstitution Inflammatory Syndrome in a Patient with Human Immunodeficiency Virus

European Journal of Case Reports in Internal Medicine, 2022
Paradoxical immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-positive patients initiating antiretroviral treatment (ART) is caused by restored immunity to specific antigens, resulting in worsening of a pre-existing
Nida Siddiqui, Brett Stephen Mansfield, Nine-Paula Olmesdahl, Peter Swart, Jeremy Nel   +4 more
doaj   +2 more sources

Post coronavirus-disease-vaccination immune reconstitution inflammatory syndrome in tuberculosis treatment: a case report [PDF]

Journal of Medical Case Reports
Background Tuberculosis immune reconstitution inflammatory syndrome is an uncommon condition caused by excessive immune response against Mycobacterium tuberculosis.
Aadit Mehta, Alok Pant
doaj   +2 more sources

Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report [PDF]

BMC Infectious Diseases, 2020
Background Cryptococcal meningitis (CCM) is a common and deadly disease among HIV-infected patients. Notable about CCM is its association with the immune reconstitution inflammatory syndrome (IRIS).
Ssegujja Boniface Joseph Otto, Paul E. George, Rebecca Mercedes, Nicolette Nabukeera‐Barungi   +3 more
openalex   +2 more sources

Drug allergy and non-HIV immune reconstitution inflammatory syndrome

Allergology International, 2022
Non-HIV immune reconstitution inflammatory syndrome (non-HIV IRIS) is associated with the recovery from an immunocompromised condition. It is defined as inflammatory disorders caused by antigens, including drugs or pathogenic microorganisms present prior
Hirohiko Sueki, Yuko Watanabe, Seiko Sugiyama, Yoshiko Mizukawa   +3 more
doaj   +2 more sources

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME IN HIV INFECTION

Инфекция и иммунитет, 2018
Antiretroviral therapy (ART) leads to suppression of HIV replication, contributes to increase in the number of CD4-lymphocytes count and  partial restoration or activation of the immune system.
E. V. Boeva, N. A. Belyakov
doaj   +3 more sources

Immune Reconstitution Inflammatory Syndrome Following Remission of Cushing’s Syndrome and Review of Literature [PDF]

Indian Journal of Endocrinology and Metabolism
The current study aims to report cases of immune reconstitution inflammatory syndrome (IRIS) following Cushing’s syndrome (CS) treatment and elucidate various presentations of IRIS and its management.
Mintu M. Baruah, Umanath Adhikari, Trupti Prasad, Biona D. Konsam, Liza Das, Aman Sharma, Sanjay K. Bhadada, Rama Walia   +7 more
doaj   +2 more sources