Results 101 to 110 of about 78,926 (342)

Borderline tuberculoid leprosy: A manifestation of immune reconstitution inflammatory syndrome in a human immunodeficiency virus infected person

Indian Journal of Dermatology, 2006
Immune reconstitution inflammatory syndrome describes a collection of inflammatory disorders associated with paradoxical deterioration of various pre-existing processes following start of highly active antiretroviral therapy (HAART) in human ...
Mukhopadhyay Partha, Pal Shekhar, Mallik Sudeshna, Biswas Surajit, Saha Bibhuti   +4 more
doaj  

Tuberculosis IRIS : a mediastinal problem [v1; ref status: indexed, http://f1000r.es/8h]

F1000Research, 2013
We present a case of a 39 years old male patient with Acquired Immune Deficiency Syndrome (AIDS) who developed Mycobacterium tuberculosis related Immune Reconstitution Inflammatory Syndrome (IRIS) after initiation of Highly Active Antiretroviral Therapy (
Leonardo Valentin, Andrew DiNardo, Elizabeth Chiao, Laila Woc-Colburn, Arun Nachiappan   +4 more
doaj   +1 more source

Acquired immunodeficiency syndrome-related progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome: prevalence, main characteristics, and outcomes in a Brazilian center

Arquivos de Neuro-Psiquiatria, 2023
Background Progressive multifocal leukoencephalopathy (PML) - immune reconstitution inflammatory syndrome (IRIS) in people living with HIV/AIDS (PLWHA) has been rarely described in low- and middle-income countries.
Monize Nascimento Santana, Raphaela Ferrari, Arthur Cassa Macedo, Rosa Maria Nascimento Marcusso, Ruan de Andrade Fernandes, José Ernesto Vidal   +5 more
doaj   +1 more source

Case Report: Orbital Myositis and Myasthenia Gravis as Symptoms of Immune Reconstitution Inflammatory Syndrome in a Patient With Human Immunodeficiency Virus Infection

Frontiers in Immunology, 2020
We present a case of a 37-year-old man with HIV infection who had been on antiretroviral therapy for one year. He was admitted to our hospital with red and swollen eyes, acute onset progressive exophthalmos, and intermittent diplopia endured for 7 days ...
Yanli Wang, Ning Zhao, Jun Yang, Y. Wen
semanticscholar   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Acute Cytomegalovirus Colitis Presenting during Primary HIV Infection: an Unusual Case of an Immune Reconstitution Inflammatory Syndrom [PDF]

, 2017
Severe ulcerous cytomegalovirus pancolitis developed during primary human immunodeficiency virus (HIV) infection in a patient who underwent early combination antiretroviral treatment.
Bossart, Walter, Gaspert, Ariana, Grube, Christina, Gü nthard, Huldrych F., Laffer, Reto, von Both, Ulrich   +5 more
core  

Monocyte Phenotype and IFN-γ-Inducible Cytokine Responses Are Associated with Cryptococcal Immune Reconstitution Inflammatory Syndrome. [PDF]

, 2017
A third of adults with AIDS and cryptococcal meningitis (CM) develop immune reconstitution inflammatory syndrome (IRIS) after initiating antiretroviral therapy (ART), which is thought to result from exaggerated inflammatory antigen-specific T cell ...
Bohjanen, Paul R, Boulware, David R, Cose, Stephen, Janoff, Edward N, Joloba, Moses, Mayanja-Kizza, Harriet, Meya, David B, Okurut, Samuel, Wahl, Sharon, Yukari Manabe, Carol, Zziwa, Godfrey   +10 more
core   +1 more source

Prospective international study of incidence and predictors of immune reconstitution inflammatory syndrome and death in people with HIV and severe lymphopenia.

Clinical Infectious Diseases, 2019
BACKGROUND Patients with HIV and low CD4 counts starting antiretroviral therapy (ART) are at high risk for immune reconstitution inflammatory syndrome (IRIS) and death.
I. Sereti, V. Sheikh, D. Shaffer, N. Phanuphak, E. Gabriel, Jing Wang, M. Nason, G. Roby, Hellen Ngeno, F. Kirui, A. Pau, J. Mican, Adam W. Rupert, R. Bishop, B. Agan, N. Chomchey, N. Teeratakulpisarn, S. Tansuphaswadikul, D. Langat, Josphat Kosgei, M. French, J. Ananworanich, F. Sawe   +22 more
semanticscholar   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source