Results 21 to 30 of about 43,379 (243)

Matrix Degradation in Human Immunodeficiency Virus Type 1-Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study. [PDF]

, 2017
Background: Extensive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process
Coussens, AK, Elkington, PT, Friedland, JS, Goliath, R, Meintjes, G, Opondo, C, Peyper, JM, Tadokera, R, Tezera, LB, Walker, NF, Wilkinson, KA, Wilkinson, RJ   +11 more
core   +5 more sources

Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique. [PDF]

, 2016
There is limited data on the epidemiology of Immune Reconstitution Inflammatory Syndrome (IRIS) in rural sub-Saharan Africa. A prospective observational cohort study was conducted to assess the incidence, clinical characteristics, outcome and predictors ...
Alonso, Pedro, Ayala, Edgar, Gascón i Brustenga, Joaquim, Letang, Emilio, Menéndez, Clara, Miró Meda, José M., Naniche, Denise, Nhampossa, Tacilta   +7 more
core   +3 more sources

Immune Reconstitution Inflammatory Syndrome in children

South African Journal of Radiology, 2017
Immune Reconstitution Inflammatory Syndrome (IRIS) refers to a collection of inflammatorydisorders, predominantly related to infectious processes that manifest after the initiation ofantiretroviral therapy (ART) and can be classified as unmasking or ...
Nasreen Mahomed, Gary Reubenson
doaj   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das, Shubhamay Adhikary, Ranjit Kumar Das, Antara Banerjee, Arun Kumar Radhakrishnan, Sujay Paul, Surajit Pathak, Asim K. Duttaroy   +7 more
wiley   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

Journal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone, Gerges Abdelsayed, Fianait Bligh, Fatma Al Qattan, Saifullah Syed, Prateepan Varatharajullu, Augustin Msellati, Daniela Mwipatayi, Maimoona Azhar, Andrew Malone, Saulat H. Fatimi, Claire Conway, Aamir Hameed   +12 more
wiley   +1 more source

Hansen's disease in association with immune reconstitution inflammatory syndrome

Indian Dermatology Online Journal, 2016
Immune reconstitution inflammatory syndrome is characterized by a paradoxical worsening of an existing infection or disease process, soon after initiation of highly active antiretroviral therapy.
Anju George, Suja Vidyadharan
doaj   +1 more source

Cortactin: A universal host cytoskeletal target of Gram‐negative and Gram‐positive bacterial pathogens

Molecular Microbiology, Volume 118, Issue 6, Page 623-636, December 2022., 2022
In host‐pathogen interactions, actin‐cytoskeletal dynamics play a crucial role in successful adherence, invasion, and intracellular motility by many intruding microbes. To achieve this goal, bacterial pathogens target major host regulators, one of which is the key actin‐binding protein and class‐II actin nucleation‐promoting factor cortactin.
Irshad Sharafutdinov, Jakob Knorr, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer   +4 more
wiley   +1 more source

Tumor necrosis factor antagonists for paradoxical inflammatory reactions in the central nervous system tuberculosis: Case report and review [PDF]

, 2021
Rationale: Paradoxical reaction/immune reconstitution inflammatory syndrome is common in patients with central nervous system tuberculosis. Management relies on high-dose corticosteroids and surgery when feasible.
Escrich, Cristina, Grau, Imma, Grijota, María D., Llaberia, Mariona, Majòs, Carles, Santín Cerezales, Miguel   +5 more
core   +1 more source

A Severe Case of Molluscum Contagiosum Immune Reconstitution Inflammatory Syndrome in a Patient with Human Immunodeficiency Virus

European Journal of Case Reports in Internal Medicine, 2022
Paradoxical immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-positive patients initiating antiretroviral treatment (ART) is caused by restored immunity to specific antigens, resulting in worsening of a pre-existing
Nida Siddiqui, Brett Stephen Mansfield, Nine-Paula Olmesdahl, Peter Swart, Jeremy Nel   +4 more
doaj   +1 more source

A network-based biomarkers discovery of Cold/Hot ZHENG chronic gastritis and Cold/Hot herbs of formulae [PDF]

arXiv, 2023
Objective: To discover biomarkers and uncover the mechanism of Cold/Hot ZHENG (syndrome in traditional Chinese medicine) chronic gastritis (CG) and Cold/Hot herbs in traditional Chinese medicine (TCM) formulae on systematic biology. Background: CG is a common inflammatory disease and the diagnosis of CG in TCM can be classified into Cold ZHENG ...
arxiv