Results 81 to 90 of about 43,379 (243)

Peptide strings clues to the genesis and treatment of rheumatoid arthritis: rebuilding self-protective immunity amid fungal ruins [PDF]

open access: yesarXiv, 2008
A recent application of the peptide strings concept has yielded novel perceptions on cell growth regulation, for instance that of oncoprotein metastasis. Here, this interdisciplinary approach at the boundary between physics and biology has been applied to gain a more profound insight into rheumatoid arthritis.
arxiv  

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

open access: yesSmall Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu   +12 more
wiley   +1 more source

Insights into pathogenic events of HIV-associated Kaposi sarcoma and immune reconstitution syndrome related Kaposi sarcoma [PDF]

open access: yes, 2008
A decrease in the incidence of human immune deficiency virus-associated Kaposi sarcoma (HIV-KS) and regression of some established HIV-KS lesions is evident after the introduction of highly active anti-retroviral treatment (HAART), and is attributed to ...
A Cattelan   +116 more
core   +2 more sources

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Immune reconstitution inflammatory syndrome associated with disseminated histoplasmosis and TNF-alpha inhibition

open access: yesMedical Mycology Case Reports, 2019
Endemic fungal infections are a significant problem for patients on TNF-alpha inhibitors. Immune reconstitution inflammatory syndrome, IRIS, can present in patients with waning TNF-alpha inhibition and an endemic fungal infection.
Theodore Wright   +3 more
doaj  

Immune Reconstitution Inflammatory Syndrome Occurring in a Kidney Transplant Patient with Extrapulmonary Tuberculosis

open access: yesCase Reports in Transplantation, 2017
Tuberculosis (TB) occurring in solid organ transplantation (SOT) is associated with significant morbidity and mortality usually due to delays in diagnosis, drug toxicity encountered with antimycobacterial therapy, and drug-drug interactions.
Jose Iglesias   +3 more
doaj   +1 more source

JC Polyomavirus, progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome: a review

open access: yesAIDS Research and Therapy, 2020
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat   +3 more
doaj   +1 more source

A physiological model of the inflammatory-thermal-pain-cardiovascular interactions during a pathogen challenge [PDF]

open access: yesarXiv, 2019
Uncontrolled, excessive production of pro-inflammatory mediators from immune cells and traumatized tissues can cause systemic inflammatory issues like sepsis, one of the ten leading causes of death in the United States and one of the three leading causes of death in the intensive care unit.
arxiv  

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Acute Cryptococcal Immune Reconstitution Inflammatory Syndrome in a Patient on Natalizumab [PDF]

open access: yes, 2016
Presented is the first case of acute immune reconstitution inflammatory syndrome (IRIS)-associated cryptococcal meningoencephalitis in a patient on natalizumab for multiple sclerosis.
Drwiega, Joseph C.   +4 more
core   +2 more sources

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