Should anti-CD20 be used as an immune reconstitution therapy? [PDF]
Smets I, Wokke B, Smolders J.
europepmc +3 more sources
Immune Reconstitution and “Unmasking” of Tuberculosis during Antiretroviral Therapy [PDF]
Abstract Tuberculosis (TB) is the most common opportunistic disease in HIV-infected patients during the initial months of antiretroviral therapy (ART) and presents a great challenge to ART programs in resource-limited settings. The mechanisms underlying development of TB in this period are complex. Some cases may represent progression
Stephen D, Lawn +3 more
openaire +2 more sources
Thyroid dysfunction following immune reconstitution therapy
Medication effects on the immune system often lead to the development of adverse events such as autoimmune diseases. The thyroid gland is organ whose embryonic development features are predisposed spontaneous and induced lesions with various autoimmune effects.
Galina A. Melnichenko +2 more
openaire +2 more sources
Cryptococcal Immune Reconstitution Inflammatory Syndrome following Alemtuzumab Therapy [PDF]
Alemtuzumab is a lymphocyte ablative agent that may cause susceptibility to severe opportunistic infections similar to those seen in AIDS. Pathogen-specific immune reconstitution syndromes can complicate antiretroviral therapy and immune recovery in HIV-infected patients.
Paul R, Ingram +3 more
openaire +2 more sources
Introduction Immune reconstitution inflammatory syndrome is a well-known complication in HIV-infected patients after initiation of highly active antiretroviral therapy resulting in rapid CD4+ cell count recovery and suppression of viral load.
Niederstadt Thomas +6 more
doaj +1 more source
Crusted scabies-associated immune reconstitution inflammatory syndrome
Background Despite the widely accepted association between crusted scabies and human immunodeficiency virus (HIV)-infection, crusted scabies has not been included in the spectrum of infections associated with immune reconstitution inflammatory syndrome ...
Fernández-Sánchez Mónica +3 more
doaj +1 more source
Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection. [PDF]
During acute and early HIV-1 infection (AEI), up to 60% of CD4(+) T cells in the lamina propria of the lower gastrointestinal (GI) tract are lost as early as 2-4 wk after infection. Reconstitution in the peripheral blood during therapy with highly active
Saurabh Mehandru +11 more
doaj +1 more source
Hansen's disease in association with immune reconstitution inflammatory syndrome
Immune reconstitution inflammatory syndrome is characterized by a paradoxical worsening of an existing infection or disease process, soon after initiation of highly active antiretroviral therapy.
Anju George, Suja Vidyadharan
doaj +1 more source
Persistent Cryptococcal Brain Infection despite Prolonged Immunorecovery in an HIV-Positive Patient
Background. HIV-positive people starting combined antiretroviral therapy may develop immune reconstitution to latent or treated opportunistic infections. Immune reconstitution to cerebral Cryptococcus is poorly understood and can be fatal.
Tom Wingfield +6 more
doaj +1 more source
Immunopathogenesis of immune reconstitution disease in HIV patients responding to antiretroviral therapy [PDF]
The aim of this article is to review the most recent literature regarding the immunopathogenesis of pathogen-associated immune reconstitution disease and to discuss the role of immune activation and various effector molecules and cells such as macrophages, effector and regulatory T cells, and natural killer cells in immune reconstitution disease.Many ...
Kestens, L. +2 more
openaire +3 more sources

