Results 81 to 90 of about 292,750 (306)

Probing Cellular Activity Via Charge‐Sensitive Quantum Nanoprobes

Advanced Materials, EarlyView.
A new quantum sensing modality detects shifts in zero‐field splitting caused by charge rearrangement with diamond nanocrystals in response to cellular activity. These electric‐field‐driven effects provide an alternative to temperature‐based interpretations, enabling real‐time, single‐cell readout of inflammation.
Uri Zvi, Shivam Mundhra, David Ovetsky, Qing Chen, Aidan R. Jones, Stella Wang, Maria J. Román‐Vazquez, Marie Kim, Udoka M. Ibeh, Michele Ferro, Kunle Odunsi, Marina C. Garassino, Michael E. Flatté, Melody A. Swartz, Denis R. Candido, Aaron Esser‐Kahn, Peter C. Maurer   +16 more
wiley   +1 more source

Mechanistic insights into neutrophil involvement in liver transplant ischemia-reperfusion injury and rejection

Frontiers in Immunology
Ischemia-reperfusion injury (IRI) and subsequent rejection remain the paramount pathological barriers to long-term graft survival following liver transplantation.
Zhipeng She, Hailun Cai, Xinqiang Li, Jinhui Chen, Ying Chen, Jinzhen Cai, Bin Wu   +6 more
doaj   +1 more source

Cervical Cancer-Associated Human Papillomavirus 16 E7 Oncoprotein Inhibits Induction of Anti-Cancer Immunity by a CD4+ T Cell Dependent Mechanism [PDF]

, 2009
Attempts to develop therapeutic vaccines against cervical cancer have been proven difficult. One of the major causes of the failure is due to the use of the wrong mouse models based on transplantable tumours in testing the efficacy of vaccines.
Germain J. Fernando, Jie Zhong, Marion E. G. Brunck, Xiao Song Liu   +3 more
core   +2 more sources

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

Advanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton, Chris R. Bowen, Hamideh Khanbareh   +2 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Accelerating Discovery to Deployment: Argonne's Materials Engineering Research Facility (MERF) and Its Role in Scaling Materials Technologies for Water and Resource Solutions

Advanced Materials Technologies, EarlyView.
In this Perspective, we highlight the processing science and scale‐up capabilities of the Materials Engineering Research Facility (MERF) at the U.S. Department of Energy's Argonne National Laboratory, with an emphasis on practical solutions for sustainable water and critical resource recovery. We demonstrate how national laboratories bridge fundamental
Yuepeng Zhang, Bratin Sengupta, Xiaoao Shi, Haihui Pu, Jeffrey W. Elam, Gregory K. Krumdick, Jessica Durham Macholz, Allison Bennett Irion, Junhong Chen, Seth B. Darling   +9 more
wiley   +1 more source

Early tolerance in pediatric liver allograft recipients [PDF]

, 1994
The authors report on six pediatric liver transplant recipients for whom allograft tolerance occurred shortly after transplantation (ie, less than 1.5 years). All the patients had associated life-threatening viral complications.
Adrianna Zeevi, Andreas G. Tzakis, Bakr Nour, Calne, Hector Ramos, Hoffman, Jorge Reyes, Keenan, Lee, Murase, Nancy Reinsmoen, Powrie, Reinsmoen, Reyes, Rolides, Romagnani, Satoru Todo, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Takeuchi, Thomas E. Starzl, Tzakis   +25 more
core   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source