Results 1 to 10 of about 2,786,821 (240)
Zearalenone and the Immune Response [PDF]
Zearalenone (ZEA) is an estrogenic fusariotoxin, being classified as a phytoestrogen, or as a mycoestrogen. ZEA and its metabolites are able to bind to estrogen receptors, 17β-estradiol specific receptors, leading to reproductive disorders which include low fertility, abnormal fetal development, reduced litter size and modification at the level of ...
Cristina Valeria Bulgaru+3 more
openaire +3 more sources
Glycobiology of immune responses [PDF]
Unlike their protein “roommates” and their nucleic acid “cousins," carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function are tied is the nontemplate nature of their synthesis and the resulting heterogeneity.
Gabriel A. Rabinovich+3 more
openaire +5 more sources
Transcriptome-wide analysis reveals different categories of response to a standardised immune challenge in a wild rodent [PDF]
Individuals vary in their immune response and, as a result, some are more susceptible to infectious disease than others. Little is known about the nature of this individual variation in natural populations, or which components of immune pathways are most
Arriero, E+7 more
core +4 more sources
Immune Responses to Retroviruses [PDF]
Retroviruses are genome invaders that have shared a long history of coevolution with vertebrates and their immune system. Found endogenously in genomes as traces of past invasions, retroviruses are also considerable threats to human health when they exist as exogenous viruses such as HIV.
Saez-Cirion, Asier, Manel, Nicolas
openaire +4 more sources
Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives [PDF]
Neuroinflammation, the complex immune response of the central nervous system (CNS), when sustained, is a common denominator in the etiology and course of all major neurological diseases, including neurodevelopmental, neurodegenerative, and psychiatric ...
Berwian+11 more
core +2 more sources
Signatures of the Immune Response [PDF]
A compendium of global gene expression measurements from DNA microarray analysis of immune cells identifies gene expression signatures defining various lineages, differentiation stages, and signaling pathways. Germinal center (GC) B cells represent a discrete stage of differentiation with a unique gene expression signature. This includes genes involved
Lloyd T. Lam+6 more
openaire +3 more sources
Dissecting interferon-induced transcriptional programs in human peripheral blood cells [PDF]
Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell ...
David A. Relman+7 more
core +7 more sources
The immune response to malaria in utero. [PDF]
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source
Regulatory immune cells in transplantation [PDF]
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control the innate immune response triggered by the injured ...
Bushell, Andrew+2 more
core +1 more source
Global dynamics of cell mediated immunity in viral infection models with distributed delays [PDF]
In this paper, we investigate global dynamics for a system of delay differential equations which describes a virus-immune interaction in \textit{vivo}.
Nakata, Yukihiko
core +3 more sources