Results 11 to 20 of about 12,342,164 (400)

Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines

open access: yesToxins, 2021
Cancer is characterized by the development of abnormal cells that divide in an uncontrolled way and may spread into other tissues where they may infiltrate and destroy normal body tissue.
Carolina Yukiko Kisaki   +9 more
doaj   +1 more source

Dissecting interferon-induced transcriptional programs in human peripheral blood cells [PDF]

open access: yes, 2010
Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell ...
David A. Relman   +7 more
core   +7 more sources

Humoral Immune Response to SARS-CoV-2 in Iceland

open access: yesNew England Journal of Medicine, 2020
Background Little is known about the nature and durability of the humoral immune response to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
D. Gudbjartsson   +61 more
semanticscholar   +1 more source

Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases

open access: yesScientific Reports, 2020
Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically ...
Amanda F. Asega   +7 more
doaj   +1 more source

Immune Responses to Retroviruses [PDF]

open access: yesAnnual Review of Immunology, 2018
Retroviruses are genome invaders that have shared a long history of coevolution with vertebrates and their immune system. Found endogenously in genomes as traces of past invasions, retroviruses are also considerable threats to human health when they exist as exogenous viruses such as HIV.
Saez-Cirion, Asier, Manel, Nicolas
openaire   +3 more sources

Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2020
As a zoonotic disease that has already spread globally to several million human beings and possibly to domestic and wild animals, eradication of coronavirus disease 2019 (COVID‐19) appears practically impossible.
A. K. Azkur   +9 more
semanticscholar   +1 more source

Contradictory roles of lipid metabolism in immune response within the tumor microenvironment

open access: yesJournal of Hematology & Oncology, 2021
Complex interactions between the immune system and tumor cells exist throughout the initiation and development of cancer. Although the immune system eliminates malignantly transformed cells in the early stage, surviving tumor cells evade host immune ...
Weina Yu   +7 more
semanticscholar   +1 more source

The immune response to malaria in utero. [PDF]

open access: yes, 2020
Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core   +1 more source

PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?

open access: yesBMC Cancer, 2018
Background The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival.
Ramón Cantero-Cid   +13 more
doaj   +1 more source

Signatures of the Immune Response [PDF]

open access: yesImmunity, 2001
A compendium of global gene expression measurements from DNA microarray analysis of immune cells identifies gene expression signatures defining various lineages, differentiation stages, and signaling pathways. Germinal center (GC) B cells represent a discrete stage of differentiation with a unique gene expression signature. This includes genes involved
Lloyd T. Lam   +6 more
openaire   +3 more sources

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