Results 21 to 30 of about 12,660,283 (403)
Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines
Toxins, 2021 Cancer is characterized by the development of abnormal cells that divide in an uncontrolled way and may spread into other tissues where they may infiltrate and destroy normal body tissue.
Carolina Yukiko Kisaki +9 more
doaj +1 more source
Contradictory roles of lipid metabolism in immune response within the tumor microenvironment
Journal of Hematology & Oncology, 2021 Complex interactions between the immune system and tumor cells exist throughout the initiation and development of cancer. Although the immune system eliminates malignantly transformed cells in the early stage, surviving tumor cells evade host immune ...
Weina Yu +7 more
semanticscholar +1 more source
Dissecting interferon-induced transcriptional programs in human peripheral blood cells [PDF]
, 2010 Interferons are key modulators of the immune system, and are central to the control of many diseases. The response of immune cells to stimuli in complex populations is the product of direct and indirect effects, and of homotypic and heterotypic cell ...
David A. Relman +7 more
core +7 more sources
Innate immune response restarts adaptive immune response in tumors
Frontiers in Immunology, 2023 The imbalance of immune response plays a crucial role in the development of diseases, including glioblastoma. It is essential to comprehend how the innate immune system detects tumors and pathogens. Endosomal and cytoplasmic sensors can identify diverse cancer cell antigens, triggering the production of type I interferon and pro-inflammatory cytokines.
Wen-shan Li +11 more
openaire +3 more sources
The immune response to malaria in utero. [PDF]
, 2020 Malaria causes tremendous early childhood morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effective in neonates.
Feeney, Margaret E
core +1 more source
Scientific Reports, 2020 Envenoming by viperid snakes results in a complex pattern of tissue damage, including hemorrhage, which in severe cases may lead to permanent sequelae. Snake venom metalloproteinases (SVMPs) are main players in this pathogenesis, acting synergistically ...
Amanda F. Asega +7 more
doaj +1 more source
Zearalenone and the Immune Response
Toxins, 2021 Zearalenone (ZEA) is an estrogenic fusariotoxin, being classified as a phytoestrogen, or as a mycoestrogen. ZEA and its metabolites are able to bind to estrogen receptors, 17β-estradiol specific receptors, leading to reproductive disorders which include ...
C. Bulgaru +3 more
semanticscholar +1 more source
PD-L1/PD-1 crosstalk in colorectal cancer: are we targeting the right cells?
BMC Cancer, 2018 Background The analysis of tumour-infiltrating immune cells within patients’ tumour samples in colorectal cancer (CRC) has become an independent predictor of patient survival.
Ramón Cantero-Cid +13 more
doaj +1 more source
Scientific Reports, 2018 Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been proposed as ZIKV congenital syndrome ...
R. S. Azevedo +18 more
semanticscholar +1 more source
Humoral Immune Response to SARS-CoV-2 in Iceland
New England Journal of Medicine, 2020 Background Little is known about the nature and durability of the humoral immune response to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
D. Gudbjartsson +49 more
semanticscholar +1 more source