Results 21 to 30 of about 12,342,164 (400)

Glial Cells: Role of the Immune Response in Ischemic Stroke

open access: yesFrontiers in Immunology, 2020
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of morbidity and mortality worldwide. The post-stroke immune response has recently emerged as a new breakthrough target in the treatment strategy for ischemic stroke ...
Shenbin Xu   +4 more
semanticscholar   +1 more source

The perioperative immune response [PDF]

open access: yesCurrent Opinion in Critical Care, 2015
A host of immune modulators are now available in clinical practice. The perioperative period is characterized by profound alterations in host immunity, which can result in poor outcomes, which include infection, cancer recurrence and organ failure. Manipulation of the perioperative immune response has the potential to improve outcomes.
O'Dwyer, MJ, Owen, HC, Torrance, HDT
openaire   +4 more sources

Immune Response, Inflammation, and the Clinical Spectrum of COVID-19

open access: yesFrontiers in Immunology, 2020
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly extended to become a global sanitary and economic emergency. Its etiological agent is the coronavirus SARS-CoV-2.
L. Garcia
semanticscholar   +1 more source

SARS-CoV-2 IgG seropositivity in a cohort of 449 non-hospitalized individuals during Spanish COVID-19 lockdown

open access: yesScientific Reports, 2021
The Coronavirus Disease of 2019 (COVID-19) pandemic caused by SARS-CoV-2 led the Spanish government to impose a national lockdown in an attempt to control the spread of the infection.
Patricia Torres Martínez   +10 more
doaj   +1 more source

Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins

open access: yesToxins, 2021
Hemorrhage induced by snake venom metalloproteinases (SVMPs) is a complex phenomenon that involves capillary disruption and blood extravasation. HF3 (hemorrhagic factor 3) is an extremely hemorrhagic SVMP of Bothrops jararaca venom.
Luciana Bertholim   +7 more
doaj   +1 more source

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

open access: yesScientific Reports, 2018
Zika virus (ZIKV) has recently caused a pandemic disease, and many cases of ZIKV infection in pregnant women resulted in abortion, stillbirth, deaths and congenital defects including microcephaly, which now has been proposed as ZIKV congenital syndrome ...
R. S. Azevedo   +18 more
semanticscholar   +1 more source

The many faces of the anti-COVID immune response

open access: yesJournal of Experimental Medicine, 2020
This Perspective explores the contributions of the innate and adaptive immune systems to both viral control as well as toxicity during COVID-19 infections and offers suggestions to both understand and therapeutically modulate anti-COVID immunity.
S. Vardhana, J. Wolchok
semanticscholar   +1 more source

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

open access: yes, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D   +5 more
core   +2 more sources

Myeloid Cell-Derived Arginase in Cancer Immune Response

open access: yesFrontiers in Immunology, 2020
Amino acid metabolism is a critical regulator of the immune response, and its modulating becomes a promising approach in various forms of immunotherapy.
T. Grzywa   +6 more
semanticscholar   +1 more source

ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei

open access: yesFrontiers in Cell and Developmental Biology, 2020
DNA double-strand breaks (DSBs) are among the most deleterious lesions that threaten genome integrity. To address DSBs, eukaryotic cells of model organisms have evolved a complex network of cellular pathways that are able to detect DNA damage, activate a
Paula Andrea Marin   +10 more
doaj   +1 more source

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