Results 31 to 40 of about 12,342,164 (400)
Immune Response Modulation by Tumor-Secreted Glycosphingolipids [PDF]
, 2014 Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) arenow recognized as having critical effects on cellular physiology, including proliferation, differentiation, viraltransformation and ontogenesis.
Cely, Ingrid +3 more
core +1 more source
Annual Review of Pathology, 2020 Immune checkpoint inhibitors (ICIs) have made an indelible mark in the field of cancer immunotherapy. Starting with the approval of anti-cytotoxic T lymphocyte-associated protein 4 (anti-CTLA-4) for advanced-stage melanoma in 2011, ICIs-which now also ...
Sreya Bagchi, Robert Yuan, E. Engleman
semanticscholar +1 more source
Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells [PDF]
, 2019 The gingival epithelium is a physical and immunological barrier to the microbiota of the oral cavity, which interact through soluble mediators with the immune cells that patrol the tissue at the gingival epithelium.
Bradshaw, David +8 more
core +4 more sources
Signaling in the immune response [PDF]
WormBook, 2006 Many pathogens that can infect C. elegans have been described, including some that co-exist with the nematode in its natural environment. This chapter describes our current understanding of the different innate immune responses of C. elegans that follow infection.
openaire +2 more sources
Pharmaceuticals, 2019 (1) Background: Treatment of patients with rheumatoid arthritis (RA) with an anti-IL-6 receptor (anti-IL-6R) monoclonal antibody (tocilizumab) has been found to influence iron metabolism.
Renata Ribeiro +3 more
doaj +1 more source
Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity [PDF]
, 2015 The dysregulation of endometrial immune response to bacterial lipopolysaccharide (LPS) has been implicated in uterine disease and infertility in the postpartum dairy cow, although the mechanisms are not clear.
Abudureyimu, A +4 more
core +1 more source
microRNAs and the immune response
Current Opinion in Pharmacology, 2009 Although the immune response is predominantly controlled at the transcriptional level, microRNA-mediated RNA interference is emerging as an important regulatory mechanism that operates at the translation level. Specifically, recent studies indicate that those miRNAs that are selectively and/or highly expressed in immune cells including the miR-17-92 ...
Mark A. Lindsay, Eleni Tsitsiou
openaire +3 more sources
npj Vaccines, 2021 Novel tuberculosis (TB)-vaccines preferably should (i) boost host immune responses induced by previous BCG vaccination and (ii) be directed against Mycobacterium tuberculosis (Mtb) proteins expressed throughout the Mtb infection-cycle.
Mariateresa Coppola +7 more
doaj +1 more source
Crosstalk Between ER Stress, Autophagy and Inflammation
Frontiers in Medicine, 2021 The endoplasmic reticulum (ER) is not only responsible for protein synthesis and folding but also plays a critical role in sensing cellular stress and maintaining cellular homeostasis.
Sandhya Chipurupalli +2 more
doaj +1 more source
Screening vaccine formulations for biological activity using fresh human whole blood. [PDF]
, 2014 Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity must reflect the expected immune response, while for non-vaccine therapeutic agents, such as ...
Aboutorabian, Sepideh +9 more
core +1 more source