Results 41 to 50 of about 289,700 (218)

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar, Altschul, Arturo Talavera, Beales, Beckmann, Bosch, Burritt, Burritt, Clark, Cohen, Collins, Cuthbert, David I. Stott, de la Cruz, Delmastro, Ela M. Perez, Emini, Enshell-Seijffers, Felici, Folgori, Folgori, Frank Camacho, Gomara, Hollinger, Hoogenboon, Irving, Lemon, Lemon, Lemon, Lemon, Lemon, Lemon, Marston, Martin, Mattioli, Nainan, Neduva, Nevis Amin, Osmany G. Larralde, Partidos, Perea, Perez, Ping, Ping, Prezzi, Raiza Martinez, Reed, Sambrook, Scholfield, Stapleton, Stapleton, Stapleton, Verdaguer, Wan, Zhang   +54 more
core   +1 more source

«FREE» AND «BOUND» ANTIBODIES AGAINST HIV–1 STRUCTURE PROTEINS AT EARLY STAGE OF THE DISEASE

Медицинская иммунология, 2014
. Using ELISA and immunoblotting we have monitored the activity of “free” antibodies against virus structure proteins in the sera of HIV–infected patients at the stage of the developing humoral immune response. Further, a comparative assessment of “free”
G. A. Rjazanova, V. P. Kocksin, R. V. Khamzina   +2 more
doaj   +1 more source

In vitro antiviral activity of a double-stranded RNA sodium salt-based medicinal product against SARS-CoV-2

Биопрепараты: Профилактика, диагностика, лечение, 2023
Scientific relevance. Innate immune activation in the early phases of COVID-19 infection and subsequent interferon induction may help control viral replication and protect cells not yet infected with SARS-CoV-2.
G. M. Ignatyev, E. Yu. Shustova, E. A. Rogozhina, P. A. Belyi, K. Ya. Zaslavskaya, V. A. Merkulov   +5 more
doaj   +1 more source

Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]

, 2013
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando, Aguilar, Alicia, Alvarez, Mayling, Amin, Nevis, Caballero, Yamira, Camacho, Frank, Díaz, Daiyana, García, Angélica, Guzmán, María Guadalupe, Pupo, Maritza, Reyes, Osvalda, Stott, David I.   +11 more
core   +2 more sources

GeSERA: General-domain Summary Evaluation by Relevance Analysis [PDF]

arXiv, 2021
We present GeSERA, an open-source improved version of SERA for evaluating automatic extractive and abstractive summaries from the general domain. SERA is based on a search engine that compares candidate and reference summaries (called queries) against an information retrieval document base (called index). SERA was originally designed for the biomedical
arxiv  

Study of humoral and cellular immunity following the immunization of C57Bl/6 mice with a prototype of the inactivated Chikungunya vaccine

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Chikungunya virus infection is a problem for the health care system of affected regions due to the lack of specific prevention, as well as effective antiviral drugs.
Elena V. Otrashevskaia, Konstantin V. Kaa, Alexey S. Oksanich, Nikita V. Murashko, Alexander G. Kusliy, Anatoliy G. Krasko, Vitaly V. Zverev, George M. Ignatyev   +7 more
doaj   +1 more source

Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing Gn protects mice against rift valley fever virus [PDF]

, 2010
Background: Rift Valley fever (RVF) is an arthropod-borne viral zoonosis. Rift Valley fever virus (RVFV) is an important biological threat with the potential to spread to new susceptible areas. In addition, it is a potential biowarfare agent. Methodology/
A Jouan, A Zaki, B Botros, BH Bird, BS Peters, CS Schmaljohn, CS Schmaljohn, Daniel G. Bausch, DB Wallace, DV Lim, FR Toapanta, FR Toapanta, G Lorenzo, GF Meadors 3rd, H Caplen, I Watanabe, J Lubroth, J Meegan, J Naslund, J Naslund, JA Mitchell, JF Bower, JF Bower, JR Haynes, JT van Oirschot, K Keegan, K Spik, KA Hubbard, M Mkrtichyan, MA Kutzler, Mark T. Heise, MT Heise, N Lagerqvist, Nitin Bhardwaj, P Hunter, P Jansen van Vuren, P Nguku, P Pittman, P Pushko, P Vialat, PR Pittman, PW Dempsey, R Gorchakov, R Gorchakov, R Randall, RJ Daubney, S Won, SA Kamal, SR Gerrard, SR Gerrard, T Shoemaker, TA Madani, TD Green, Ted M. Ross, TM Pertmer, TM Pertmer, TM Ross, TM Ross, UB Balasuriya   +58 more
core   +4 more sources

Serological diagnosis of toxoplasmosis: evaluation of the commercial test recomLine Toxoplasma IgG immunoblot (Mikrogen) based on recombinant antigens

Parasite, 2022
Background: IgG detection to determine immune status to Toxoplasma gondii infection and seroconversion mainly relies on ELISA techniques and, if necessary, on a confirmatory test, Western blot.
Jean-Pierre Vincent, Miozzo Julien, Fricker-Hidalgo Hélène, Garnaud Cécile, Robert Marie Gladys, Pelloux Hervé, Brenier-Pinchart Marie-Pierre   +6 more
doaj   +1 more source

A 53 KDa Glycan Antigen of Hydatid Cyst Wall May Involve in Evasion from Host Immune System

Advanced Biomedical Research, 2018
Background: Recent studies have shown that similar host glycan antigens are expressed by helminths such as Echinococcus granulosus hydatid cysts to evade from host immune system.
Raheleh Rafiei Sefiddashti, Seyedeh Maryam Sharafi, Soltan Ahmad Ebrahimi, Lame Akhlaghi, Ali Moosavi, Abasali Eskandarian, Hossein Yousofi Darani   +6 more
doaj   +1 more source

Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins

BMC Immunology, 2021
Background The natural antibody responses to B-cell epitopes from dengue structural proteins were assessed using immune sera from people having well-defined past dengue infections with one of the four serotypes.
Mahesha N. Nadugala, Chandima Jeewandara, Ramesh S. Jadi, Gathsaurie N. Malavige, Aravinda M. de Silva, Prasad H. Premaratne, Charitha L. Goonasekara   +6 more
doaj   +1 more source