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Plasmodium suppresses immunity
Trends in Microbiology, 1999Dendritic cells (DCs) are the most potent of the antigen-presenting cells and have the unique ability to both initiate a primary response against a microorganism and amplify the secondary response upon re-exposure. Rissoan et al.1xReciprocal control of T helper cell and dendritic cell differentiation. Rissoan, M-C. et al. Science.
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Suppression of the Immune Response by Nasal Immunization
Clinical Immunology and Immunopathology, 1994Intranasal immunization results in both a mucosal and a systemic immune response in humans. Intranasal tetanus toxoid immunization in humans causes an increased serum IgA1 antibody response to tetanus toxoid following a subsequent intramuscular immunization. We hypothesized that intranasal priming with a novel protein antigen, keyhole limpet hemocyanin
F B, Waldo +3 more
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Immune Suppression and Chemical Carcinogenesis
1975It is well known that a number of tumors arising in man are induced by chemical carcinogens. Some authors even state that the majority of tumors arising in man are due to chemical agents (17, 12, 13). Since publication of the first case reports concerning the possibility of development of tumors due to prolonged immunosuppression in transplantation ...
R, Kroes, J W, Weiss, J H, Weisburger
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Targeting Immune Suppression in Cancer
Cancer Discovery, 2016Abstract Researchers have figured out a way to switch the immunosuppressive phenotype of tumor-associated macrophages to one that's immunostimulatory. By inhibiting PI3Kγ in these macrophages, they significantly suppressed tumor growth in mice; when anti–PD-1 therapy was added to PI3Kγ inhibition, complete and sustained tumor eradication
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Immune suppression at high altitude
Annals of Emergency Medicine, 1987This paper is a review and interpretation of prior studies that have investigated the effects of hypoxia on immune function. A summary of current methods used to assess immune effector cell function in human beings is presented using in vitro models of mononuclear cell activation.
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Chemical Suppression of Adaptive Immunity
1967Publisher Summary The chapter constitutes a monumental review of current knowledge of chemical suppression of adaptive immunity. The chapter's interpretation is based on the hypothesis that there are two functionally distinct lymphoid systems: (1) thymus dependent involved in delayed-type hypersensitivity and (2) dependent on the bursa of fabricius ...
A E, Gabrielsen, R A, Good
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1989
A pathogenic virus has to overcome the immune system in order to establish a successful infection. Most viruses seem to succeed by having a temporal advantage over the specific immune defense mechanisms that are elicited only when the organism encounters the virus.
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A pathogenic virus has to overcome the immune system in order to establish a successful infection. Most viruses seem to succeed by having a temporal advantage over the specific immune defense mechanisms that are elicited only when the organism encounters the virus.
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Plasma-mediated immune suppression
Pediatric Allergy and Immunology, 2013Plasma is a rich mixture of immune regulatory factors that shape immune cell function. This immunomodulatory role of plasma is especially important in neonates. To maintain in utero feto-maternal tolerance and to allow for microbial colonization after birth, the neonatal immune system is biased against pro-inflammatory responses while favoring immune ...
Belderbos, Mirjam E. +3 more
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Iatrogenic immune suppression.
Pediatric nursing, 1995Tissue and organ transplants are now fairly common medical procedures encountered by pediatric nurses practicing in acute care settings. The understanding of what is known about the immune response to foreign antigens provides strong evidence of the immunologic barriers to organ and tissue transplantation.
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Metabolic programming and immune suppression in the tumor microenvironment
Cancer Cell, 2023Emily Arner, Jeffrey C Rathmell
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