Results 91 to 100 of about 3,573,912 (317)
Towards a Conceptual Framework for Innate Immunity [PDF]
Proceedings of the 4th International Conference on Artificial
Immune Systems (ICARIS 2005), Lecture Notes in Computer Science 3627, Banff,
Canada, p 112-125, 2010 Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity and, adopting a conceptual framework, asks how these can be incorporated into artificial models.
arxiv
Aging-induced fragility of the immune system [PDF]
arXiv, 2020 The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system undergoes immunosenescence, characterized by declined performance or malfunction in either immune branch, which can lead to disease and death.
arxiv
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Trials, 2020 Background Gastroesophageal reflux disease (GERD) is a major cause of chronic cough. GERD-induced chronic cough is difficult to diagnose because some patients do not complain of any gastrointestinal (GI) reflux symptoms.
Yeon Hee Bhang +12 more
doaj +1 more source
Two novel immunization strategies for epidemic control in directed scale-free networks with nonlinear infectivity [PDF]
arXiv, 2018 In this paper, we propose two novel immunization strategies, i.e., combined immunization and duplex immunization, for SIS model in directed scale-free networks, and obtain the epidemic thresholds for them with linear and nonlinear infectivities. With the suggested two new strategies, the epidemic thresholds after immunization are greatly increased. For
arxiv
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
OMiCC: An expanded and enhanced platform for meta-analysis of public gene expression data
STAR Protocols, 2022 Summary: OMiCC (OMics Compendia Commons) is a biologist-friendly web platform that facilitates data reuse and integration. Users can search over 40,000 publicly available gene expression studies, annotate and curate samples, and perform meta-analysis ...
Candace C. Liu +5 more
doaj
Immuno-epidemiology of a population structured by immune status: a mathematical study of waning immunity and immune system boosting [PDF]
arXiv, 2014 When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment boosts the immune system thus prolonging the time in which a recovered individual is immune.
arxiv
CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE [PDF]
, 1969 Gustavo Cudkowicz +2 more
openalex +3 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source