Results 11 to 20 of about 3,197,655 (339)
PlGF, immune system and hypertension [PDF]
, 2015 The huge diffusion of hypertension and its associated complications has a significant impact on public health [1]. However, despite the high prevalence of essential hypertension and many efforts of research, the basic pathophysiological causes remain
CARNEVALE, DANIELA, LEMBO, Giuseppe
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Artificial Immune Systems [PDF]
, 2013 The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self or nonself substances. It does this with the help of a distributed task force that has the intelligence to take action from a local and also a global perspective using
Aickelin, U, Dasgupta, D, Gu, F
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A comparative study of immune system based genetic algorithms in dynamic environments [PDF]
, 2006 Copyright @ 2006 ACMDiversity and memory are two major mechanisms used in biology to keep the adaptability of organisms in the ever-changing environment in nature.
Yang, S
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PI3K in T Cell Adhesion and Trafficking
Frontiers in Immunology, 2021 PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of
Kristoffer H. Johansen +5 more
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Immune system simulation online [PDF]
Bioinformatics, 2011 Abstract Motivation: The recognition of antigenic peptides is a major event of an immune response. In current mesoscopic-scale simulators of the immune system, this crucial step has been modeled in a very approximated way. Results: We have equipped an agent-based model of the immune system with immuno-informatics methods ...
Rapin N, Lund O, Castiglione F
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Frontiers in Immunology, 2014 Natural killer (NK) cells play an essential role in the fight against tumor development. Over the last years, the progress made in the NK cell biology field and in deciphering how NK cell function is regulated, is driving efforts to utilize NK cell-based
Cristina eEguizabal +11 more
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Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
Nature Communications, 2022 The catalytic chaperone tapasin assists peptide loading onto MHC-I molecules for antigen presentation and immune recognition. Here, the authors present crystal structures that provide insights into the molecular mechanism of tapasin-mediated peptide ...
Jiansheng Jiang +11 more
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Essays in Biochemistry, 2016 All organisms are connected in a complex web of relationships. Although many of these are benign, not all are, and everything alive devotes significant resources to identifying and neutralizing threats from other species. From bacteria through to primates, the presence of some kind of effective immune system has gone hand in hand with evolutionary ...
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Artificial Immune Systems [PDF]
, 2006 29 pages,4 figures,
Aickelin, U, Dasgupta, D
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From traumatic childhood to cocaine abuse: the critical function of the immune system [PDF]
, 2018 Background: Experiencing traumatic childhood is a risk factor for developing substance use disorder (SUD), but the mechanisms that underlie this relationship have not been determined.
Aricò, Eleonora +17 more
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