Results 11 to 20 of about 24,697,135 (341)
The Role of Minerals in the Optimal Functioning of the Immune System
Nutrients, 2022 Minerals fulfil a wide variety of functions in the optimal functioning of the immune system. This review reports on the minerals that are essential for the immune system’s function and inflammation regulation.
C. Weyh +3 more
semanticscholar +1 more source
Mapping the developing human immune system across organs
bioRxiv, 2022 Recent advances in single cell genomics technologies have facilitated studies on the developing immune system at unprecedented scale and resolution. However, these studies have focused on one or a few organs and were thus limited in understanding the ...
Chenqu Suo +25 more
semanticscholar +1 more source
SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain
Communications Biology, 2023 The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang +6 more
doaj +1 more source
Obesity, Inflammation, and Immune System in Osteoarthritis
Frontiers in Immunology, 2022 Obesity remains the most important risk factor for the incidence and progression of osteoarthritis (OA). The leading cause of OA was believed to be overloading the joints due to excess weight which in turn leads to the destruction of articular cartilage.
Udhaya Nedunchezhiyan +5 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Podocalyxin (PODXL), a cell surface sialomucin expressed in diverse types of normal and malignant cells, mediates cellular adhesion to extracellular matrix and cell-to-cell interaction.
Laura Amo +4 more
doaj +1 more source
Ubiquitin in the immune system [PDF]
EMBO reports, 2013 Ubiquitination is a post-translational modification process that has been implicated in the regulation of innate and adaptive immune responses. There is increasing evidence that both ubiquitination and its reversal, deubiquitination, play crucial roles not only during the development of the immune system but also in the orchestration of an immune ...
Zinngrebe Julia +3 more
openaire +5 more sources
Systemic immunity in cancer [PDF]
Nature Reviews Cancer, 2021 Immunotherapy has revolutionized cancer treatment, but efficacy remains limited in most clinical settings. Cancer is a systemic disease that induces many functional and compositional changes to the immune system as a whole. Immunity is regulated by interactions of diverse cell lineages across tissues.
Kamir J. Hiam-Galvez +2 more
openaire +5 more sources
Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology
Journal of Neuroinflammation, 2023 Background Increasing evidence supports a key role for peripheral immune processes in the pathophysiology of Alzheimer’s disease (AD), highlighting an intricate interplay between brain resident glial cells and both innate and adaptive peripheral immune ...
Grégoire Stym-Popper +8 more
doaj +1 more source
A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection
Nutrients, 2020 Immune support by micronutrients is historically based on vitamin C deficiency and supplementation in scurvy in early times. It has since been established that the complex, integrated immune system needs multiple specific micronutrients, including ...
A. Gombart, A. Pierre, S. Maggini
semanticscholar +1 more source
Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus
Nature Reviews Neurology, 2021 Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a considerable body of evidence indicates pathological alterations in central and peripheral immune responses that change over time.
Brianne M. Bettcher +3 more
semanticscholar +1 more source