Results 81 to 90 of about 24,833,277 (264)

Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

open access: yesCell Reports, 2022
Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify several
Sinu P. John   +13 more
doaj  

The immune system in chickens , [PDF]

open access: yesAvian Pathology, 1974
The most sophisticated feature of the immune system expressed in vertebrates is recognition of foreign molecules by distinct types of immunocompetent cells. Birds are the first vertebrates in which a clear dichotomy of the lymphoid system has been established: 1. Thymus-derived (T) lymphocytes, the effector cells in cell-mediated (immunity and 2. Bursa-
openaire   +3 more sources

Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa.

open access: yesPhysiological Reviews, 2018
Because of the compartmentalization of disciplines that shaped the academic landscape of biology and biomedical sciences in the past, physiological systems have long been studied in isolation from each other.
R. Dantzer
semanticscholar   +1 more source

The Canadian collaborative project on genetic susceptibility to multiple sclerosis cohort population structure and disease etiology

open access: yesFrontiers in Neurology
BackgroundPrevious genetic and epidemiological studies have examined subpopulations from the Canadian Collaborative Project on Genetic Susceptibility to Multiple Sclerosis (CCPGSMS) patient cohort, but an encompassing analysis of the study population has
Alison M. Pagalilauan   +14 more
doaj   +1 more source

RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair

open access: yesNature Communications, 2016
Antigen receptor diversity relies on careful DNA cleavage and repair. Here the authors identify a functional interplay between RAG2 and XLF during V(D)J recombination, revealing an important role for the RAG complex in repairing induced DNA double-strand
Chloé Lescale   +8 more
doaj   +1 more source

Role of Vitamin A in the Immune System

open access: yesJournal of Clinical Medicine, 2018
Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body.
Zhiyi Huang   +4 more
semanticscholar   +1 more source

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

open access: yesFrontiers in Immunology, 2018
Antigen presentation is a cellular process that involves a number of steps, beginning with the production of peptides by proteolysis or aberrant synthesis and the delivery of peptides to cellular compartments where they are loaded on MHC class I (MHC-I ...
Kannan Natarajan   +8 more
doaj   +1 more source

THE PROPERDIN SYSTEM AND IMMUNITY [PDF]

open access: bronze, 1956
Ralph Wedgwood   +2 more
openalex   +1 more source

Mercury and its toxic effects on fish

open access: yesAIMS Environmental Science, 2017
Mercury (Hg) and its derivative compounds have been parts of widespread pollutants of the aquatic environment. Since Hg is absorbed by fish and passed up the food chain to other fish-eating species, it does not only affect aquatic ecosystems but also ...
Patricia Morcillo   +2 more
doaj   +1 more source

Evolution of the immune system in humans from infancy to old age

open access: yesProceedings of the Royal Society B: Biological Sciences, 2015
This article reviews the development of the immune response through neonatal, infant and adult life, including pregnancy, ending with the decline in old age.
Anna Katharina Simon   +2 more
semanticscholar   +1 more source

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