Results 21 to 30 of about 3,749,228 (399)
Biology Bulletin Reviews, 2022 This review presents, in detail and from multiple angles, the classification of diseases of the immune system during different periods of a person’s life, including immune-associated and immune-dependent diseases, their phenomenology, disease triggers, and the mechanisms of regulation of immune reactivity.
Zemskov, V. M. +7 more
openaire +1 more source
Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways
mSystems, 2021 Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models ...
Nathan P. Manes, Aleksandra Nita-Lazar
doaj +1 more source
mSystems, 2021 Macrophages and monocytes are innate immune cells playing an important role in orchestrating the initial innate immune response to bacterial infection and the tissue damage.
Orna Ernst +11 more
doaj +1 more source
Frontiers in Immunology, 2022 T helper-2 (Th2) cells and type 2 innate lymphoid cells (ILC2s) play crucial roles during type 2 immune responses; the transcription factor GATA3 is essential for the differentiation and functions of these cell types.
Rama K. Gurram +11 more
doaj +1 more source
The Innate Immune System in Alzheimer’s Disease [PDF]
International Journal of Cell Biology, 2013 Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloidβ(Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (CAA) and aggregated tau protein in the form of intraneuronal neurofibrillary tangles (NFT).
Allal Boutajangout, Thomas Wisniewski
openaire +3 more sources
Thirty years of resistance: Zig-zag through the plant immune system
The Plant Cell, 2022 Understanding the plant immune system is crucial for using genetics to protect crops from diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response system. The first plant Resistance (R) gene was cloned in 1992 . Since then,
Bruno Pok Man Ngou +2 more
semanticscholar +1 more source
Frontiers in Immunology, 2023 Foxp3 is regarded as the major transcription factor for T regulatory (Treg) cells and expression of Foxp3 is used to identify and quantitate Treg cells in mouse models.
Lyra Morina +9 more
doaj +1 more source
Histopathology of the gut in rheumatic diseases [PDF]
, 2018 The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F. +4 more
core +1 more source
Nutrients, 2021 The most prevalent diseases of our time, non-communicable diseases (NCDs) (including obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising worldwide.
C. García-Montero +16 more
semanticscholar +1 more source
LPS Tolerance Inhibits Cellular Respiration and Induces Global Changes in the Macrophage Secretome
Biomolecules, 2021 Inflammatory response plays an essential role in the resolution of infections. However, inflammation can be detrimental to an organism and cause irreparable damage.
Joseph Gillen +7 more
doaj +1 more source