Results 41 to 50 of about 3,483,015 (354)
Extracellular Vesicles and Immune System in Ageing and Immune Diseases
Experimental Neurobiology, 2021 Immune system is essential for host homeostasis. Immune cells communicate with each other by binding to receptors or by releasing vesicles including chemokines and cytokines. Under healthy circumstances, immune cell-derived factors are critical for cellular growth, division and function, whereas under conditions such as ageing and inflammatory states ...
Jong Eun Lee, So Yeong Cheon
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Frontiers in Immunology, 2022 T helper-2 (Th2) cells and type 2 innate lymphoid cells (ILC2s) play crucial roles during type 2 immune responses; the transcription factor GATA3 is essential for the differentiation and functions of these cell types.
Rama K. Gurram +11 more
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Frontiers in Immunology, 2023 Foxp3 is regarded as the major transcription factor for T regulatory (Treg) cells and expression of Foxp3 is used to identify and quantitate Treg cells in mouse models.
Lyra Morina +9 more
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DNA, the Immune System, and Atopic Disease [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2004 The prevalence and severity of atopic diseases (atopic dermatitis, asthma, and allergic rhinitis) have increased over recent decades, particularly in industrialized nations. Atopic dermatitis, like asthma, is more common in older siblings and in less crowded houses and with late entry to day care, increased maternal education, and higher socio-economic
Iftikhar Hussain, Joel N. Kline
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LPS Tolerance Inhibits Cellular Respiration and Induces Global Changes in the Macrophage Secretome
Biomolecules, 2021 Inflammatory response plays an essential role in the resolution of infections. However, inflammation can be detrimental to an organism and cause irreparable damage.
Joseph Gillen +7 more
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GATA3 induces the pathogenicity of Th17 cells via regulating GM-CSF expression
Frontiers in Immunology, 2023 T-bet-expressing Th17 (T-bet+RORγt+) cells are associated with the induction of pathology during experimental autoimmune encephalomyelitis (EAE) and the encephalitic nature of these Th17 cells can be explained by their ability to produce GM-CSF. However,
Matthew J. Butcher +8 more
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The role of the immune system in kidney disease [PDF]
Clinical and Experimental Immunology, 2018 Summary The immune system and the kidneys are closely linked. In health the kidneys contribute to immune homeostasis, while components of the immune system mediate many acute forms of renal disease and play a central role in progression of chronic kidney disease.
Tecklenborg, Josefine +3 more
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Regulation of Macrophage Polarization in Allergy by Noncoding RNAs
Non-Coding RNA, 2023 Allergy is a type 2 immune reaction triggered by antigens known as allergens, including food and environmental substances such as peanuts, plant pollen, fungal spores, and the feces and debris of mites and insects.
Osamu Ishibashi +2 more
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Alzheimer's Disease and the Immune System [PDF]
SOJ Neurology, 2015 Alzheimer's disease (AD) has been known for over 100 years, but has only just become a pressing matter at the end of the 21st century. AD is a disease related to the aging of the individual, and has its burden over the population has continued to increase as medicine and technology are continuing to lengthen the lives of individuals.
Chuanhai Cao +2 more
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Cholinergic Modulation of the Immune System in Neuroinflammatory Diseases [PDF]
Diseases, 2021 Frequent diseases of the CNS, such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and psychiatric disorders (e.g., schizophrenia), elicit a neuroinflammatory response that contributes to the neurodegenerative disease process itself. The immune and nervous systems use the same mediators, receptors, and cells to regulate the immune and ...
Reale, Marcella, Costantini, Erica
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