Results 51 to 60 of about 3,492,274 (391)

Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota

open access: yesmSystems, 2017
The bodies of mammals are hosts to vast microbial communities composed of trillions of bacteria from thousands of species, whose effects on health and development have begun to be appreciated only recently.
Nathan P. Manes   +5 more
doaj   +1 more source

Lentivirus-mediated Conditional Gene Expression

open access: yesBio-Protocol, 2021
The ability to identify the role of a particular gene within a system is dependent on control of the expression of that gene. In this protocol, we describe a method for stable, conditional expression of Nod-Like receptors (NLRs) in THP-1 cells using a ...
Leah Rommereim   +4 more
doaj   +1 more source

Organization of the Skin Immune System and Compartmentalized Immune Responses in Infectious Diseases

open access: yesClinical Microbiology Reviews, 2019
The skin is an organ harboring several types of immune cells that participate in innate and adaptive immune responses. The immune system of the skin comprises both skin cells and professional immune cells that together constitute what is designated skin ...
J. Quaresma
semanticscholar   +1 more source

The innate immune system in demyelinating disease [PDF]

open access: yesImmunological Reviews, 2012
Summary:  Demyelinating diseases such as multiple sclerosis are chronic inflammatory autoimmune diseases with a heterogeneous clinical presentation and course. Both the adaptive and the innate immune systems have been suggested to contribute to their pathogenesis and recovery. In this review, we discuss the role of the innate immune system in mediating
Francisco J. Quintana   +2 more
openaire   +3 more sources

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

open access: yesScientific Reports, 2021
MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4+ T helper cells which are key players in autoimmune diseases.
Anju Singh   +13 more
doaj   +1 more source

Immune System Response in Alzheimer's Disease [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1989
ABSTRACT:Involvement of the immune system in the pathogenesis of Alzheimer's disease was demonstrated in two ways: by the attachment of complement proteins to diseased tissue, and by the activation of cells associated with the immune system. Alzheimer brain tissue was stained immunohistochemically by antibodies to components of the classical, but not ...
Haruhiko Akiyama   +3 more
openaire   +2 more sources

Intestinal microbiota influences non-intestinal related autoimmune diseases [PDF]

open access: yes, 2018
Indexación: Scopus.The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner.
Bonifaz, L.C.   +8 more
core   +2 more sources

Recovery of Capsaicinoids and Other Phytochemicals Involved With TRPV-1 Receptor to Re-valorize Chili Pepper Waste and Produce Nutraceuticals

open access: yesFrontiers in Sustainable Food Systems, 2021
The hot chili pepper industry represents one of the most important staple foods in Mexico and many Asian countries. Nowadays, large amounts of waste materials are produced from the pepper supply chain that could be used as a source to obtain ...
Hector Emmanuel Cortés-Ferré   +4 more
doaj   +1 more source

Aspects of Gut Microbiota and Immune System Interactions in Infectious Diseases, Immunopathology, and Cancer

open access: yesFrontiers in Immunology, 2018
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea, and protozoans, bringing to the host organism a dowry of cells and genes more numerous than its own.
V. Lazǎr   +8 more
semanticscholar   +1 more source

Type 2 Diabetes and its Impact on the Immune System

open access: yesCurrent Diabetes Reviews, 2020
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi   +3 more
semanticscholar   +1 more source

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