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The bodies of mammals are hosts to vast microbial communities composed of trillions of bacteria from thousands of species, whose effects on health and development have begun to be appreciated only recently.
Nathan P. Manes+5 more
doaj +1 more source
Lentivirus-mediated Conditional Gene Expression
The ability to identify the role of a particular gene within a system is dependent on control of the expression of that gene. In this protocol, we describe a method for stable, conditional expression of Nod-Like receptors (NLRs) in THP-1 cells using a ...
Leah Rommereim+4 more
doaj +1 more source
Organization of the Skin Immune System and Compartmentalized Immune Responses in Infectious Diseases
The skin is an organ harboring several types of immune cells that participate in innate and adaptive immune responses. The immune system of the skin comprises both skin cells and professional immune cells that together constitute what is designated skin ...
J. Quaresma
semanticscholar +1 more source
The innate immune system in demyelinating disease [PDF]
Summary: Demyelinating diseases such as multiple sclerosis are chronic inflammatory autoimmune diseases with a heterogeneous clinical presentation and course. Both the adaptive and the innate immune systems have been suggested to contribute to their pathogenesis and recovery. In this review, we discuss the role of the innate immune system in mediating
Francisco J. Quintana+2 more
openaire +3 more sources
Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4+ T helper cells which are key players in autoimmune diseases.
Anju Singh+13 more
doaj +1 more source
Immune System Response in Alzheimer's Disease [PDF]
ABSTRACT:Involvement of the immune system in the pathogenesis of Alzheimer's disease was demonstrated in two ways: by the attachment of complement proteins to diseased tissue, and by the activation of cells associated with the immune system. Alzheimer brain tissue was stained immunohistochemically by antibodies to components of the classical, but not ...
Haruhiko Akiyama+3 more
openaire +2 more sources
Intestinal microbiota influences non-intestinal related autoimmune diseases [PDF]
Indexación: Scopus.The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner.
Bonifaz, L.C.+8 more
core +2 more sources
The hot chili pepper industry represents one of the most important staple foods in Mexico and many Asian countries. Nowadays, large amounts of waste materials are produced from the pepper supply chain that could be used as a source to obtain ...
Hector Emmanuel Cortés-Ferré+4 more
doaj +1 more source
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea, and protozoans, bringing to the host organism a dowry of cells and genes more numerous than its own.
V. Lazǎr+8 more
semanticscholar +1 more source
Type 2 Diabetes and its Impact on the Immune System
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi+3 more
semanticscholar +1 more source