Results 51 to 60 of about 3,483,015 (354)

IFN-mediated negative feedback supports bacteria class-specific macrophage inflammatory responses

open access: yeseLife, 2019
Despite existing evidence for tuning of innate immunity to different classes of bacteria, the molecular mechanisms used by macrophages to tailor inflammatory responses to specific pathogens remain incompletely defined.
Rachel A Gottschalk   +10 more
doaj   +1 more source

Involvement of Probiotics and Postbiotics in the Immune System Modulation

open access: yesBiologics, 2021
Intestinal microbiota interacts with other systems, especially the immune system, which is responsible for protecting the body by recognizing “stranger” (pathogen associated molecular patterns-PAMPs) and “danger” (damage-associated molecular patterns ...
Neslihan Yeşilyurt   +3 more
semanticscholar   +1 more source

Measles-induced immune amnesia and its effects in concurrent epidemics [PDF]

open access: yes, 2021
It has been recently discovered that the measles virus can wipe out the adaptive immune system, destroying B lymphocytes and reducing the diversity of non-specific B cells of the infected host. In particular, this implies that previously acquired immunization from vaccination or direct exposition to other pathogens could be erased in a phenomenon named
arxiv   +1 more source

A new immune disease: systemic hypertension

open access: yesClinical Kidney Journal, 2023
ABSTRACT Systemic hypertension is the most common medical comorbidity affecting the adult population globally, with multiple associated outcomes including cerebrovascular diseases, cardiovascular diseases, vascular calcification, chronic kidney disease, metabolic syndrome and mortality.
Sidar Copur   +4 more
openaire   +2 more sources

Lentivirus-mediated Conditional Gene Expression

open access: yesBio-Protocol, 2021
The ability to identify the role of a particular gene within a system is dependent on control of the expression of that gene. In this protocol, we describe a method for stable, conditional expression of Nod-Like receptors (NLRs) in THP-1 cells using a ...
Leah Rommereim   +4 more
doaj   +1 more source

The Outcome of COVID-19 in Patients with a History of Taking Rituximab: A Narrative Review [PDF]

open access: yesIranian Journal of Medical Sciences, 2021
Coronavirus disease 2019 (COVID-19) is a recently emerging disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Notably, the safety of immunosuppressive medications is a major concern during an infectious disease pandemic ...
Pourya Yarahmadi   +3 more
doaj   +1 more source

Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota

open access: yesmSystems, 2017
The bodies of mammals are hosts to vast microbial communities composed of trillions of bacteria from thousands of species, whose effects on health and development have begun to be appreciated only recently.
Nathan P. Manes   +5 more
doaj   +1 more source

Impact of the Innate Inflammatory Response on ICU Admission and Death in Hospitalized Patients with COVID-19

open access: yesBiomedicines, 2021
Objective: To describe the capacity of a broad spectrum of cytokines and growth factors to predict ICU admission and/or death in patients with severe COVID-19.
Jorge Monserrat   +16 more
doaj   +1 more source

Organization of the Skin Immune System and Compartmentalized Immune Responses in Infectious Diseases

open access: yesClinical Microbiology Reviews, 2019
The skin is an organ harboring several types of immune cells that participate in innate and adaptive immune responses. The immune system of the skin comprises both skin cells and professional immune cells that together constitute what is designated skin ...
J. Quaresma
semanticscholar   +1 more source

The innate immune system in demyelinating disease [PDF]

open access: yesImmunological Reviews, 2012
Summary:  Demyelinating diseases such as multiple sclerosis are chronic inflammatory autoimmune diseases with a heterogeneous clinical presentation and course. Both the adaptive and the innate immune systems have been suggested to contribute to their pathogenesis and recovery. In this review, we discuss the role of the innate immune system in mediating
Francisco J. Quintana   +2 more
openaire   +3 more sources

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