Results 51 to 60 of about 3,749,228 (399)
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core +4 more sources
Frontiers in Immunology, 2018 The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea, and protozoans, bringing to the host organism a dowry of cells and genes more numerous than its own.
V. Lazǎr +8 more
semanticscholar +1 more source
Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
Scientific Reports, 2021 MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4+ T helper cells which are key players in autoimmune diseases.
Anju Singh +13 more
doaj +1 more source
Frontiers in Immunology, 2016 Analogous to other physiological systems, the immune system also demonstrates remarkable sex differences. Although the reasons for sex differences in immune responses are not precisely understood, it potentially involves differences in sex hormones ...
H. Waldmann, S. Ahmed, D. Khan
semanticscholar +1 more source
Metabolic regulation of the immune system in health and diseases: mechanisms and interventions
Signal Transduction and Targeted TherapyMetabolism, including glycolysis, oxidative phosphorylation, fatty acid oxidation, and other metabolic pathways, impacts the phenotypes and functions of immune cells.
Tengyue Hu +6 more
semanticscholar +1 more source
Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy [PDF]
, 2017 Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal antibodies (MAbs) developed for cancer immunotherapy.
Mai, Antonello +3 more
core +1 more source
Disturbed Systemic Immune Balance in Periodontal Disease
Autoimmunity, 1998 To the editorSir; Human periodontitis is a disease caused by some bacterial infections. In etiopathogene-sis, the role of disturbed local and systemic immunoregulatory mechanisms have drawn the attention. Down-regulation of local T-suppressor cells was commented as the cause of enhanced local immunoglobulin production (1).
Karaarslan, F +3 more
openaire +2 more sources
The Impact of Immune System Aging on Infectious Diseases
MicroorganismsImmune system aging is becoming a field of increasing public health interest because of prolonged life expectancy, which is not paralleled by an increase in health expectancy.
Eugenia Quiros-Roldan +3 more
semanticscholar +1 more source
BioMed Research International, 2016 Histone deacetylase (HDAC) inhibitors are powerful epigenetic regulators that have enormous therapeutic potential and have pleiotropic effects at the cellular and systemic levels.
Elizabeth E. Hull +2 more
semanticscholar +1 more source
The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
Frontiers in Immunology, 2018 Antigen presentation is a cellular process that involves a number of steps, beginning with the production of peptides by proteolysis or aberrant synthesis and the delivery of peptides to cellular compartments where they are loaded on MHC class I (MHC-I ...
Kannan Natarajan +8 more
doaj +1 more source