Results 61 to 70 of about 3,492,274 (391)

Spirochetal Lipoproteins and Immune Evasion. [PDF]

open access: yes, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani   +2 more
core   +1 more source

The Immune System Is a Natural Target for Estrogen Action: Opposing Effects of Estrogen in Two Prototypical Autoimmune Diseases

open access: yesFrontiers in Immunology, 2016
Analogous to other physiological systems, the immune system also demonstrates remarkable sex differences. Although the reasons for sex differences in immune responses are not precisely understood, it potentially involves differences in sex hormones ...
H. Waldmann, S. Ahmed, D. Khan
semanticscholar   +1 more source

RANKL biology: bone metabolism, the immune system, and beyond

open access: yesInflammation and Regeneration, 2020
Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono   +3 more
semanticscholar   +1 more source

Characteristics of Gut Microbiota and Their Association with Lymphocyte Subsets and Disease Activity in Ankylosing Spondylitis

open access: yesXiehe Yixue Zazhi, 2022
Objective  To investigate the characteristics of gut microbiome and their associations with lymphocyte subsets and disease activity in patients with ankylosing spondylitis (AS).  Methods  This study was a retrospective analysis. The subjects of the study
SONG Ziyi   +7 more
doaj   +1 more source

Innate immunity and neuroinflammation [PDF]

open access: yes, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

open access: yesCell Reports, 2022
Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify several
Sinu P. John   +13 more
doaj  

Revealing microbial recognition by specific antibodies [PDF]

open access: yes, 2015
Background: Recognition of microorganisms by antibodies is a vital component of the human immune response. However, there is currently very limited understanding of immune recognition of 50 % of the human microbiome which is made up of as yet un ...
Collado, M. Carmen   +5 more
core   +1 more source

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling

open access: yesFrontiers in Immunology, 2018
Antigen presentation is a cellular process that involves a number of steps, beginning with the production of peptides by proteolysis or aberrant synthesis and the delivery of peptides to cellular compartments where they are loaded on MHC class I (MHC-I ...
Kannan Natarajan   +8 more
doaj   +1 more source

OMiCC: An expanded and enhanced platform for meta-analysis of public gene expression data

open access: yesSTAR Protocols, 2022
Summary: OMiCC (OMics Compendia Commons) is a biologist-friendly web platform that facilitates data reuse and integration. Users can search over 40,000 publicly available gene expression studies, annotate and curate samples, and perform meta-analysis ...
Candace C. Liu   +5 more
doaj  

Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract

open access: yesFrontiers in Immunology, 2020
The intestinal tract is the largest digestive organ in the human body. It is colonized by, and consistently exposed to, a myriad of microorganisms, including bifidobacteria, lactobacillus, Escherichia coli, enterococcus, clostridium perfringens, and ...
Bolun Zhou   +7 more
semanticscholar   +1 more source

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