Results 61 to 70 of about 3,749,228 (399)

Correlations in the T Cell Response to Altered Peptide Ligands

open access: yes, 2004
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases.
Arstila   +26 more
core   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

open access: yes, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco   +15 more
core   +1 more source

Type 2 Diabetes and its Impact on the Immune System

open access: yesCurrent Diabetes Reviews, 2020
Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi   +3 more
semanticscholar   +1 more source

Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality

open access: yesFrontiers in Medicine, 2021
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga   +17 more
doaj   +1 more source

RANKL biology: bone metabolism, the immune system, and beyond

open access: yesInflammation and Regeneration, 2020
Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono   +3 more
semanticscholar   +1 more source

The Immune System [PDF]

open access: yes, 1995
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut   +1 more
core   +1 more source

Virological aspects of Epstein-Barr virus infections. [PDF]

open access: yes, 2005
Epstein-Barr virus (EBV) is usually maintained in an asymptomatic and latent form by the host immune system, and primarily by EBV-specific cytotoxic T cells (CTLs).
Kimura, Hiroshi   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Chaperone-mediated MHC-I peptide exchange in antigen presentation

open access: yesIUCrJ
This work focuses on molecules that are encoded by the major histocompatibility complex (MHC) and that bind self-, foreign- or tumor-derived peptides and display these at the cell surface for recognition by receptors on T lymphocytes (T cell receptors ...
Jiansheng Jiang   +2 more
doaj   +1 more source

Characteristics of Gut Microbiota and Their Association with Lymphocyte Subsets and Disease Activity in Ankylosing Spondylitis

open access: yesXiehe Yixue Zazhi, 2022
Objective  To investigate the characteristics of gut microbiome and their associations with lymphocyte subsets and disease activity in patients with ankylosing spondylitis (AS).  Methods  This study was a retrospective analysis. The subjects of the study
SONG Ziyi   +7 more
doaj   +1 more source

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