Results 61 to 70 of about 3,483,015 (354)
Immune System Response in Alzheimer's Disease [PDF]
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1989 ABSTRACT:Involvement of the immune system in the pathogenesis of Alzheimer's disease was demonstrated in two ways: by the attachment of complement proteins to diseased tissue, and by the activation of cells associated with the immune system. Alzheimer brain tissue was stained immunohistochemically by antibodies to components of the classical, but not ...
Haruhiko Akiyama +3 more
openaire +2 more sources
Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
Scientific Reports, 2021 MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4+ T helper cells which are key players in autoimmune diseases.
Anju Singh +13 more
doaj +1 more source
Frontiers in Immunology, 2018 The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea, and protozoans, bringing to the host organism a dowry of cells and genes more numerous than its own.
V. Lazǎr +8 more
semanticscholar +1 more source
Type 2 Diabetes and its Impact on the Immune System
Current Diabetes Reviews, 2020 Introduction: Type 2 Diabetes (T2D) is a major health problem worldwide. This metabolic disease is indicated by high blood glucose levels due to insufficient insulin production by the pancreas.
Afiat Berbudi +3 more
semanticscholar +1 more source
RANKL biology: bone metabolism, the immune system, and beyond
Inflammation and Regeneration, 2020 Receptor activator of NF-κB (RANK) ligand (RANKL) induces the differentiation of monocyte/macrophage–lineage cells into the bone–resorbing cells called osteoclasts.
T. Ono +3 more
semanticscholar +1 more source
Frontiers in Immunology, 2016 Analogous to other physiological systems, the immune system also demonstrates remarkable sex differences. Although the reasons for sex differences in immune responses are not precisely understood, it potentially involves differences in sex hormones ...
H. Waldmann, S. Ahmed, D. Khan
semanticscholar +1 more source
OMiCC: An expanded and enhanced platform for meta-analysis of public gene expression data
STAR Protocols, 2022 Summary: OMiCC (OMics Compendia Commons) is a biologist-friendly web platform that facilitates data reuse and integration. Users can search over 40,000 publicly available gene expression studies, annotate and curate samples, and perform meta-analysis ...
Candace C. Liu +5 more
doaj
Cell Reports, 2022 Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify several
Sinu P. John +13 more
doaj
The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling
Frontiers in Immunology, 2018 Antigen presentation is a cellular process that involves a number of steps, beginning with the production of peptides by proteolysis or aberrant synthesis and the delivery of peptides to cellular compartments where they are loaded on MHC class I (MHC-I ...
Kannan Natarajan +8 more
doaj +1 more source
Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract
Frontiers in Immunology, 2020 The intestinal tract is the largest digestive organ in the human body. It is colonized by, and consistently exposed to, a myriad of microorganisms, including bifidobacteria, lactobacillus, Escherichia coli, enterococcus, clostridium perfringens, and ...
Bolun Zhou +7 more
semanticscholar +1 more source