Results 71 to 80 of about 3,492,274 (391)
A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho+11 more
core +2 more sources
Nutrition and the Immune System: A Complicated Tango
Enthusiasm exists for the potential of diet to impact the immune system, prevent disease and its therapeutic potential. Herein, we describe the challenge to nutrition scientists in defining this relationship through case studies of diets and nutrients in
C. Venter+3 more
semanticscholar +1 more source
Helminths in the hygiene hypothesis:Sooner or later? [PDF]
There is increasing recognition that exposures to infectious agents evoke fundamental effects on the development and behaviour of the immune system. Moreover, where infections (especially parasitic infections) have declined, immune responses appear to be
Maizels, R. M.+2 more
core +4 more sources
Intestinal macromolecular transport supporting adaptive immunity [PDF]
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core +2 more sources
Interleukin-10 Attenuates Liver Fibrosis Exacerbated by Thermoneutrality
Background: Crosstalk between brown adipose tissue (BAT) and the liver is receiving increasing attention. This study investigated the effect of BAT dysfunction by thermoneutral (TN) housing on liver fibrosis in mice and examined the effect of secreted ...
Ha Thi Nga+17 more
doaj +1 more source
Aging and Neurodegenerative Disease: Is the Adaptive Immune System a Friend or Foe?
Neurodegenerative diseases of the central nervous system (CNS) are characterized by progressive neuronal death and neurological dysfunction, leading to increased disability and a loss of cognitive or motor functions.
K. Mayne+4 more
semanticscholar +1 more source
Chaperone-mediated MHC-I peptide exchange in antigen presentation
This work focuses on molecules that are encoded by the major histocompatibility complex (MHC) and that bind self-, foreign- or tumor-derived peptides and display these at the cell surface for recognition by receptors on T lymphocytes (T cell receptors ...
Jiansheng Jiang+2 more
doaj +1 more source
Aldosterone, Inflammation, Immune System, and Hypertension
Aldosterone is a mineralocorticoid hormone that controls body fluid and electrolyte balance. Excess aldosterone is associated with cardiovascular and metabolic diseases.
N. Ferreira+3 more
semanticscholar +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Correlations in the T Cell Response to Altered Peptide Ligands
The vertebrate immune system is a wonder of modern evolution. Occasionally, however, correlations within the immune system lead to inappropriate recruitment of preexisting T cells against novel viral diseases.
Arstila+26 more
core +1 more source